EFECTOS DEL EJERCICIO EN LA VASCULARIZACION CEREBRAL EN PACIENTES CORONARIOS

PID2020-120249RB-I00

Nombre agencia financiadora Agencia Estatal de Investigación
Acrónimo agencia financiadora AEI
Programa Programa Estatal de I+D+i Orientada a los Retos de la Sociedad
Subprograma Programa Estatal de I+D+i Orientada a los Retos de la Sociedad
Convocatoria Proyectos I+D
Año convocatoria 2020
Unidad de gestión Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020
Centro beneficiario UNIVERSIDAD DE GRANADA
Identificador persistente http://dx.doi.org/10.13039/501100011033

Publicaciones

Resultados totales (Incluyendo duplicados): 2
Encontrada(s) 1 página(s)

Effects of an exercise program on cardiometabolic and mental health in children with overweight or obesity: a secondary analysis of a randomized clinical trial

Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
  • Migueles, Jairo H.
  • Cadenas-Sánchez, Cristina
  • Lubans, David R.
  • Henriksson, Pontus
  • Torres-López, Lucía V.
  • Rodríguez Ayllon, María
  • Plaza Florido, Abel
  • Gil Cosano, José J.
  • Henriksson, Hanna
  • Escolano Margarit, María Victoria
  • Gómez Vida, José
  • Maldonado, José
  • Löf, Marie
  • Ruiz, Jonatan R.
  • Labayen Goñi, Idoia
  • Ortega, Francisco B.
Importance: Childhood obesity is a risk factor associated with type 2 diabetes, cardiovascular disease, and mental disorders later in life. Investigation of the parallel effects of a defined exercise program on cardiometabolic and mental health in children with overweight or obesity may provide new insights on the potential benefits of exercise on overall health. Objective: To investigate the effects of a 20-week exercise program on cardiometabolic and mental health in children with overweight or obesity. Design, Setting, and Participants: This secondary analysis of a parallel-group randomized clinical trial was conducted in Granada, Spain, from November 1, 2014, to June 30, 2016. Data analyses were performed between February 1, 2020, and July 14, 2022. Children with overweight or obesity aged 8 to 11 years were eligible, and the study was performed in an out-of-school context. Intervention: The exercise program included 3 to 5 sessions/wk (90 min/session) of aerobic plus resistance training for 20 weeks. The wait-list control group continued with their usual routines. Main Outcomes and Measures: Cardiometabolic outcomes as specified in the trial protocol included body composition (fat mass, fat-free mass, and visceral adipose tissue), physical fitness (cardiorespiratory, speed-agility, and muscular), and traditional risk factors (waist circumference, blood lipid levels, glucose levels, insulin levels, and blood pressure). Cardiometabolic risk score (z score) was calculated based on age and sex reference values for levels of triglycerides, inverted high-density lipoprotein cholesterol, and glucose, the mean of systolic and diastolic blood pressure, and waist circumference. An additional cardiometabolic risk score also included cardiorespiratory fitness. Mental health outcomes included an array of psychological well-being and ill-being indicators. Results: The 92 participants included in the per-protocol analyses (36 girls [39%] and 56 boys [61%]) had a mean (SD) age of 10.0 (1.1) years. The exercise program reduced the cardiometabolic risk score by approximately 0.38 (95% CI, -0.74 to -0.02) SDs; decreased low-density lipoprotein cholesterol level by -7.00 (95% CI, -14.27 to 0.37) mg/dL (to convert to mmol/L, multiply by 0.0259), body mass index (calculated as weight in kilograms divided by height in meters squared) by -0.59 (95% CI, -1.06 to -0.12), fat mass index by -0.67 (95% CI, -1.01 to -0.33), and visceral adipose tissue by -31.44 (95% CI, -58.99 to -3.90) g; and improved cardiorespiratory fitness by 2.75 (95% CI, 0.22-5.28) laps in the exercise group compared with the control group. No effects were observed on mental health outcomes. Conclusions and Relevance: In this secondary analysis of a randomized clinical trial, an aerobic plus resistance exercise program improved cardiometabolic health in children with overweight or obesity but had no effect on mental health. Trial Registration: ClinicalTrials.gov Identifier: NCT02295072., This project was supported with grants DEP2013-47540, DEP2016-79512-R, DEP2017-91544-EXP, and RYC-2011-09011 from the Spanish Ministry of Economy and Competitiveness and the Fondo Europeo de Desarrollo Regional (FEDER) and by grant PID2020-120249RB-I00 from the MCIN/AEI /10.13039/501100011033. Additional funding was obtained from the Andalusian Operational Programme supported with grant B-CTS-355-UGR18 from the European Regional Development Fund (FEDER in Spanish). Dr Cardenas-Sanchez is supported by grant FJC2018-037925-I from the Spanish Ministry of Science and Innovation and by a grant from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska Curie grant agreement No 101028929. Dr Migueles is supported by grant FPU15/02645 from the Spanish Ministry of Education, Culture and Sport, and grant 2012–00036 from the Swedish Research Council for Health, Working Life and Welfare. Dr Torres-Lopez is supported by grant FPU17/04802 from the Spanish Ministry of Science, Innovation and Universities. Dr Rodriquez-Ayllon was funded by grant DEP2017-91544-EXP from the Ramón Areces Foundation. Additional support was obtained from grant ALICIAK-2018 from the Alicia Koplowitz Foundation, University of Granada, Plan Propio de Investigación 2016, Excellence actions: Units of Excellence, Unit of Excellence on Exercise, Nutrition and Health, the Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades; and grant DEP2005-00046/ACTI from the EXERNET Research Network on Exercise and Health in Special Populations. This research was supported by grant CB22/03/00058 from the Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación and Unión Europea–European Regional Development Fund.




The Youth Fitness International Test (YFIT) battery for monitoring and surveillance among children and adolescents: a modified Delphi consensus project with 169 experts from 50 countries and territories

Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
  • Ortega, Francisco B.
  • Zhang, Kai
  • Cadenas-Sánchez, Cristina
  • Tremblay, Mark S.
  • Jurak, Gregor
  • Tomkinson, Grant R.
  • Ruiz, Jonatan R.
  • Keller, Katja
  • Nyström, Christine Delisle
  • Sacheck, Jennifer M.
  • Pate, Russell
  • Weston, Kathryn L.
  • Kidokoro, Tetsuhiro
  • Poon, Eric T.
  • Wachira, Lucy-Joy M.
  • Ssenyonga, Ronald
  • Gomes, Thayse Natacha Q.F.
  • Cristi Montero, Carlos
  • Fraser, Brooklyn J.
  • Niessner, Claudia
  • Onywera, Vincent O.
  • Liu, Yang
  • Liang, Li-Lin
  • Prince, Stephanie A.
  • Lubans, David R.
  • Lang, Justin J.
  • Delphi Fitness Expert Group
  • Ramírez Vélez, Robinson
Background: physical fitness in childhood and adolescence is associated with a variety of health outcomes and is a powerful marker of current and future health. However, inconsistencies in tests and protocols limit international monitoring and surveillance. The objective of the study was to seek international consensus on a proposed, evidence-informed, Youth Fitness International Test (YFIT) battery and protocols for health monitoring and surveillance in children and adolescents aged 618 years.
Methods: we conducted an international modified Delphi study to evaluate the level of agreement with a proposed, evidence-based, YFIT of core health-related fitness tests and protocols to be used worldwide in 6- to 18-year-olds. This proposal was based on previous European and North American projects that systematically reviewed the existing evidence to identify the most valid, reliable, health-related, safe, and feasible fitness tests to be used in children and adolescents aged 618 years. We designed a single-panel modified Delphi study and invited 216 experts from all around the world to answer this Delphi survey, of whom one-third are from low-to-middle income countries and one-third are women. Four experts were involved in the piloting of the survey and did not participate in the main Delphi study to avoid bias. We pre-defined an agreement of 80% among the expert participants to achieve consensus.
Results: we obtained a high response rate (78%) with a total of 169 fitness experts from 50 countries and territories, including 63 women and 61 experts from low- or middle-income countries/territories. Consensus (>85% agreement) was achieved for all proposed tests and protocols, supporting the YFIT battery, which includes weight and height (to compute body mass index as a proxy of body size/composition), the 20-m shuttle run (cardiorespiratory fitness), handgrip strength, and standing long jump (muscular fitness).
Conclusion: this study contributes to standardizing fitness tests and protocols used for research, monitoring, and surveillance across the world, which will allow for future data pooling and the development of international and regional sex- and age-specific reference values, health-related cut-points, and a global picture of fitness among children and adolescents., FBO's research activity is supported by the Grant PID2020-120249RB-I00 and PID2023-148404OB-I00 funded by MCIN/AEI/10.13039/501100011033 and by the Andalusian Government (Junta de Andaluc¿a, Plan Andaluz de Investigacion, ref. P20_00124), and by the Erasmus+ Sport Programme of the European Union within the project FitBack4Literacy (No. 101089829). Additional support is provided by the University of Granada, Plan Propio de Investigacion, Units of Excellence; Unit of Excellence on Exercise, Nutrition and Health (UCEENS), by the CIBERobn Physiopathology of Obesity and Nutrition, and by the Spanish Network.
in Exercise and Health, EXERNET Network (RED2022-
134800-T and EXP_99828).