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Dades primàries associades a la publicació disponible a https://doi.org/10.1371/journal.pone.0178172, Podeu consultar l'article a: http://hdl.handle.net/2445/113259, Registre de ressonància magnètica funcional de subjectes diagnosticats de Diabetes Tipus I aparellats per edat i nivell educatiu amb un grups de controls. El registre de senyal cerebral està fet a partir de dues tasques vinculades amb llenguatge. Una d'elles amb components de working memory i l'altra no. Són dades analitzables amb eines específiques de R, MathLab, SMP o FSL.

There are twenty zip files each one corresponding to a participant. The acronym PT stands for patients (from 01 to 10) and HC stands for healthy controls (from 01 to 10). Once unzipped, structural and functional data of each patient and healthy control are located in the folder indicated by the specific acronym and number of the participant (i.e. PT01). Thus, each folder contains the original functional data of the resting state sequence (fmri.nii.gz), the preprocessed functional data (fmri_res.nii.gz), the original structural T1-weighted image (T1.nii.gz) and the structural T1-weighted image after applying the brain extraction with the Brain Extraction Tool of fsl (T1_brain.nii.gz) and used to perform the co-registration with the functional data. All images are in NIfTI (Neuroimaging Computer Technology Initiative) format, as a gzip compressed file, normally used by different software as the software library FMRIB (FSL). We also provide the NIfTI file of the AAL Atlas used to parcellate the brain during the analysis (AAL_Contract_90_3MM.nii) and the corresponding text file indicating the list of regions composing the atlas (AAL_LabelID_90.txt)., Podeu consultar el document publicat a: http://hdl.handle.net/2445/161359, Dades primàries associades a un article publicat a la revista PLoS One, 2020, vol. 15, num. 1, p. e0226816 [https://doi.org/10.1371/journal.pone.0226816], We tested 10 hemianopic patients and 10 healthy participants. They were scanned in a 1.5 Tesla Philips scanner at the Borgo Roma Hospital in Verona (Italy). We collected a whole brain high-resolution (1x1x1 mm3) 3D T1-weighted image with magnetization-prepared rapid acquisition gradient echo (MPRAGE) and one hundred sixty resting state volumes with TR=2500ms, Echo Time=50ms; 30 slices with slice thickness of 4mm, Field of View = 224x224mm, time duration = 6.47m and echo train length = 39. The entire sample was were scanned during the period of time going from February 2017 until July 2018.

Study of immune correlates against malaria after vaccination with RTS,S/ASO1E: a comphrensive immunological arm of a Phase III double-blind, randomize, controlled multi-centre trial (MAL067)., Dades primàries associades a l'article publicat a NPJ Vaccines, vol. 5 [https://doi.org/10.1038/s41541-020-0192-7], The RTS,S/AS01E vaccine has shown consistent but partial vaccine efficacy in a pediatric phase 3 26 clinical trial using a 3-dose immunization schedule. A fourth dose 18 months after the primary 27 vaccination was shown to restore the waning efficacy. However, only total IgG against the 28 immunodominant malaria vaccine epitope has been analyzed following the booster. To better 29 characterize the magnitude, nature and longevity of the immune response to the booster, we 30 measured levels of total IgM, IgG and IgG1-4 subclasses against three constructs of the 31 circumsporozoite protein (CSP) and the hepatitis B surface antigen (HBsAg, also present in RTS,S) 32 by quantitative suspension array technology in 50 subjects in the phase 3 trial in Manhiça, 33 Mozambique. To explore the impact of vaccination on naturally acquired immune responses, we 34 measured antibodies to P. falciparum antigens not included in RTS,S. We found increased IgG, 35 IgG1, IgG3 and IgG4, but not IgG2 nor IgM, levels against vaccine antigens one month after the 4th 36 dose. Overall, antibody responses to the booster dose were lower than the initial peak 37 response to primary immunization and children had higher IgG and IgG1 levels than infants. 38 Higher anti-Rh5 IgG and IgG1-4 levels were detected after the booster dose, suggesting that RTS,S 39 partial protection could increase some blood stage antibody responses. Our work shows that the 40 response to the RTS,S/AS01E booster dose is different from the primary vaccine immune 41 response and highlights the dynamic changes in subclass antibody patterns upon the vaccine 42 booster and with acquisition of adaptive immunity to malaria.

Dades primàries associades a l'article publicat a PLoS One, vol. 15, p. 5, p. e0232470 [https://doi.org/10.1371/journal.pone.0232470], The sav file contains the raw data of 17 quantitative variables saved in SSPS Statistics format while the MS word file includes the description of the dataset and the names of the variables used, Raw data and data analysis scripts from the study “Executive functions, Personality traits and ADHD symptoms in adolescents: A mediation analysis”. This study aimed to analyze the associations between performance on cognitive executive function (EF) measures and FFM personality traits in a sample of adolescents with and without ADHD.