BUSCADOR RECOLECTA

Data associated with the study called "Selectively targeting tumorigenicity in osteosarcoma". Each file corresponds to the raw data of one of the figures of the paper

These data are associated to the paper with the same title and are structured according to the figures in the paper. These data correspond to the research results of the WP3 of the European Project 4D-POLYSENSE., The present dataset reports the scientific results corresponding to a scientific study where a bidimensional (2D) polypropylene flexible mesh material has been converted into a fourth dimension (4D) dynamic system. The platform is composed by a fibres of isotactic polypropylene (iPP) mesh coated with thermosensitive poly(N-isopropylacrylamide-co-N,N'-methylene bis(acrylamide) (PNIPAAm-co-MBA) hydrogel, and undergoes variations in its geometry by reversible folding/unfolding behaviour. Folding and unfolding motion in aqueous solution of bilayer and monolayer systems composed by two or one layer of hydrogel, respectively, are reported in the present dataset. Furthermore, an infrared thermographic camera and an optical microscope were used to evaluate the macroscopic and microscopic structure stimulus response in air. Additionally, PP-g-PNIPAAm meshes showed an increase in the mechanical properties (bursting strength) with respect to the uncoated mesh.

These data are associated to the paper with the same title and are structured according to the figures in the paper. These data correspond to the research results of the WP2 of the European Project 4D-POLYSENSE., The present dataset collects and reports the scientific results corresponding to a scientific study of a commercial and fully flexible versatile bilayer system, composed by a polypropylene (PP) mesh and a covalently bonded poly(N-isopropylacrylamide) (PNIPAAm) hydrogel. In this study the mechanism responsible for cell-adhesion and de-adhesion, when the PNIPAAm-co-MBA monolayer film (adherent on one hand to the PP substrate and anti-adherent on the other hand to cell proliferation) is being employed, has been elucidated. The grafting of the hydrogel was studied and the the graft yield as well as the spectroscopic characterization (FTIR and XPS) of samples treated at different concentration of the crosslinker and different grafting time are ported in the present dataset. The scientific results of cell adhesion and biocompatibility assay are also included, being the in vitro results with fibroblast (COS-1) and epithelial (MCF-7) cells obtained with a mesh modified with a porous iPP-g-PNIPAAm bilayer system, prepared via PNIPAAm grafting for 2 h at the lowest N,NI-methylene bis(acrylamide) (MBA) concentration (1 mM).

Datos recopilados en el análisis de la colecciones docentes disponibles en los repositorios institucionales de las universidades españolas.