Resultados de investigación

Proyecto HAR2016-75788-P del Gobierno de España

Dataset from the sprint events of the 2021 European Swimming Championships., Aquatics Lab. Department of Physical Education and Sports Grupo de investigación CTS-527

Experimental data of "Extremely thermostabilizing core mutations in coiled-coil mi-metic proteins of HIV-1 gp41 produce diverse effects on target binding and inhibitory activity"

Metabolic reprogramming of cancer cells represents an orchestrated network of evolving molecular and functional adaptations during oncogenic progression. In particular, how metabolic reprogramming is orchestrated in breast cancer and its decisive role in the oncogenic process and tumor evolving adaptations are well consolidated at the molecular level. Nevertheless, potential correlations between functional metabolic features and breast cancer clinical classification still represent issues that have not been fully studied to date. Accordingly, we aimed to investigate whether breast cancer cell models representative of each clinical subtype might display different metabolic phenotypes that correlate with current clinical classifications. In the present work, functional metabolic profiling was performed for breast cancer cell models representative of each clinical subtype based on the combination of enzyme inhibitors for key metabolic pathways, and isotope-labeled tracing dynamic analysis. The results indicated the main metabolic phenotypes, so-called ‘metabophenotypes’, in terms of their dependency on glycolytic metabolism or their reliance on mitochondrial oxidative metabolism. The results showed that breast cancer cell subtypes display different metabophenotypes. Importantly, these metabophenotypes are clearly correlated with the current clinical classifications., Funding: This research, including APC charges, was funded by the Spanish Agencia Estatal de Investigación (Ministry of Science and Innovation) and the European Regional Development Fund [grant numbers CTQ2014-56370-R and CTQ2017-85658-R]; the Fundación Ramón Areces; and the initiative Solidaridad Entre Montañas.

Supplementary Tables 3-6, 8-10: Table S3. Trinotate annotation report for Dactylicapnos torulosa. Annotation through blastx and blastp for predict transcript against Swissprot database. Table S4. Trinotate annotation report for Fumaria bracteosa. Annotation through blastx and blastp for predict transcript against Swissprot database. Table S5. Trinotate annotation report for Roemeria refracta. Annotation through blastx and blastp for predict transcript against Swissprot database. Table S6. Eschscholzia californica annotation through blastx against Swissprot database for transcripome transcript aligned to reference. Qseqid, query or source (e.g., gene) sequence id; seqid, subject or target (e.g., reference genome) sequence id; pident, percentage of identical matches; length, alignment length (sequence overlap); mismatch, number of mismatches; gapopen, number of gap openings; qstart, start of alignment in query; qend, end of alignment in query; sstart, start of alignment in subject; send, end of alignment in subject; evalue, expect value; bitscore, bit score. Table S8. Transcripts annotated as transcription factor through PlantTFDB. Table S9. Genes differentially expressed between colpate and porate species. Annotation through BLASTX searching against the SwissProt Database. Table S10. Functional classification of differentially expressed genes (DEGs) between colpate and porate species using Blast2GO software. Sheet 1, Blast2GO output file with annotations and functional classification for each DEG. Sheet2, summary of the number of DEGs for each functional annotation within the three different functional categories, note that each DEG can have several annotation possibilities.

We present the data of a study of the Schumann Resonance (SR) regular variations (March 2013 – February 2017) using the ground-based magnetometers from the Sierra Nevada station, Spain (37◦02’N, 3◦19’W). The study is based on the fitting parameters obtained by the Lorentzian fit, calculated for each 10-min interval record, namely, peak amplitudes, central frequencies, width of the resonances and the power spectrum integral for the first 3 SR modes. We consider three time-scales in the study: seasonal, monthly and daily variations. The processed data collected by the Sierra Nevada station are also made public with this work.

Cuestionario y datos brutos de la investigación "El Proyecto Europa: un reto cultural", en español y en inglés., El artículo aborda la pregunta de por qué las mujeres migrantes se ven más negativamente afectadas que los hombres cuando se enfrentan a comportamientos de comunicación para ellos inusuales en el país de acogida, pero, sin embargo, están más dispuestas a adaptarse al estilo de comunicación extranjero. Para responder a esta pregunta, se investigó la gestión diferente de la regulación emocional por parte de ambos sexos. Una amplia encuesta realizada entre inmigrantes españoles en Alemania llevó a la conclusión de que las mujeres inmigrantes perciben los rasgos investigados con más frecuencia y también se ven más afectadas por ellos. Pero, en comparación con los hombres, tienen una mayor capacidad para reconocer y comprender sus emociones aunque también muestran una mayor tendencia a rumiar. Sin embargo, la mayoría de las mujeres contrarrestaron esta tendencia con una mayor capacidad para regular sus emociones a través de estrategias de reparación emocional anti-rumiación. Según los datos, esta capacidad parece conducir a una mayor disposición a comprender el punto de vista del nativo y, por tanto, posiblemente a una mayor disposición a integrarse en la sociedad de acogida., This article addresses the question as to why female migrants are more negatively affected than male migrants when confronted with unfamiliar traits in communication in the host country, but they are nevertheless more willing to adapt to the foreign style of communication. To answer this question, the different management of emotional regulation (Thayer et al. 2003) by both genders was investigated. A broad survey conducted among Spanish migrants in Germany led to the conclusion that the female migrants actually perceive the investigated traits more frequently and are also more affected by them. But, in comparison to the males, they have an increased ability to recognize and understand their emotions although they also display an increased tendency to ruminate. However, most of the women counteracted this tendency with a heightened ability to regulate their emotions through anti-rumination emotional repair strategies. According to the data, this ability seems to lead to a greater willingness to understand the views of the natives and thus possibly to being more disposed to integrate into the host society.