Resultados de investigación

AGUDIZACIÓN DE LA EPOC (AEPOC), La Agudización de la Enfermedad Pulmonar Obstructiva Crónica (AEPOC) se define según la GesEPOC 2021 como un “episodio de inestabilidad clínica en un paciente EPOC como consecuencia del agravamiento de la limitación espiratoria al flujo aéreo o del proceso inflamatorio subyacente y se caracteriza por un empeoramiento agudo de los síntomas respiratorios respecto de la situación basal del individuo”., Yes

Se incluyen datos del Proyecto Pintura, poder, sociedad y naturaleza en el Quito barroco (PID2020-112852GB-I00): bibliografías, relación de instituciones en las que se ha investigado, publicaciones de los miembros del Proyecto vinculadas directamente al mismo, tabla, carteles y programas de actividades desarrolladas desde el Proyecto, A) Bibliografías (PDF): -Bibliografía del Proyecto (PDF) -Bibliografía de la monografía Pintura, poder, sociedad y naturaleza en el Quito barroco (PDF) B) Relación de publicaciones generadas por el Proyecto (PDF) C) Tablas (PDF): -Tabla de las especies citadas en las cartelas de los Tipos de la Real Audiencia de Quito (Salgueiro González 2023) (PDF) D) Relación de instituciones en las que se ha realizado el trabajo de campo del Proyecto (PDF) E) Carteles y programas de las actividades organizadas por el Proyecto (PDF y JPG): -Programa del I Simposio Internacional “Arte, historia y cultura en el Quito virreinal” (PDF) -Programa del II Simposio Internacional “Arte, historia y cultura en el Quito virreinal” (PDF) -Programa del Simposio “Mujeres pintoras y la imagen de la mujer en el Quito barroco” (PDF) -Programa del Taller del Seminario de Investigación en Historia Moderna de América (abril de 2022) (PDF) -Programa del Taller del Seminario de Investigación en Historia Moderna de América (abril de 2023) (PDF) -Programa del Taller del Seminario de Investigación en Historia Moderna de América (junio de 2024) (PDF) -Programa del Congreso “Pintura, poder, sociedad y naturaleza en el Quito barroco”. (PDF) -Cartel de Congreso “Pintura, poder, sociedad y naturaleza en el Quito barroco” (JPG) -Cartel del Simposio “Mujeres pintoras y la imagen de la mujer en el Quito barroco” (JPG) F) Publicaciones en Open Access: Se relacionan las publicaciones en Open Access. Se depositarán en idUS aquellas que cuenten con los correspondientes permisos de las editoriales. Las que pertenecen a editoriales con repositorios en línea, y que ya han publicado investigaciones del Proyecto, son las siguientes: buleria.nileon.es, e-revistes.uji.es, rio.upo.es, journals.uco.es, revistas.icanh.gov.co, editorial.ucuenca.edu.ec Martín Rodríguez, P. (2022). Del dibujo de campo a la lámina botánica: Análisis del proceso de trabajo tras una estampa de la Flora peruviana et chilensis. UCOARTE. Revista De Teoría E Historia Del Arte, 11, 67–82. https://doi.org/10.21071/ucoarte.v11i.14231 Justo Estebaranz, Á., Vásquez Hahn, M. A. y Chiva Beltrán, J. (2025, en prensa). «A fin de acreditar la alegría y congratulación que demanda un asunto tan remarcable»: Fiestas en Quito por la Independencia (1822-1830)". Potestas, nº 26. En prensa. Justo-Estebaranz, Á. (2023). La clave está en el herrero: artesanado local y robos de obras de arte y de útiles de trabajo en Quito durante los siglos XVII y XVIII. En A. Contreras-Guerrero, Á. Justo-Estebaranz, & F. Quiles (Eds.), En las sombras del Barroco. Una mirada introspectiva (pp. 305-337). Publicación Enredars/ Andavira Editora. https://rio.upo.es/rest/api/core/bitstreams/b6e40273-bc09-4cc9-b74e-37067b2b64e1/content Justo-Estebaranz, Á. (2023). El Órgano de la Iglesia del Sagrario de Cuenca: Historia e Iconografía. En Memorias del III Encuentro Nacional de Historia de la Provincia del Azuay (pp. 69-86). Universidad de Cuenca. https://editorial.ucuenca.edu.ec/omp/index.php/ucp/catalog/view/78/235/415 Montes Sánchez, M. y Justo-Estebaranz, Á. (2024). Entre retablos, adulterio y cárcel: el batihoja Vicente Egas en Cuenca. En “Y VERÉIS TODA ESTA ARENA DE CARROS DE PLATA LLENA”. ESTUDIOS SOBRE LA PLATA EN IBEROAMÉRICA De los orígenes al siglo XIX (pp. 799-814). Secretaría de Cultura. INAH. Instituto Nacional de Antropología e Historia Coordinación Nacional de Monumentos Históricos (México), Instituto de Humanismo y Tradición Clásica Universidad de León (España).

Diastereomeric excess determination of 1,3-bisulfinates. Experimental data of 1,3-bis-(sulfinyl)propanes. Experimental data of allylation of N-(benzoyl)isobutylhydrazone. Experimental data of vinyl sulfoxides. Experimental data of 1,5-bis(sulfinyl)-3-thioderivatives. Figures of regioselective oxidation of 1,5-bis(sulfinyl)-3-thioderivatives. Figures of palladium(II) and ruthenium(II) complexes formation. HPLC chromatograms of selected compounds. 1H NMR, 13C{1H} NMR and 19F NMR of selected compounds. 2D NMR of selected compounds. X-ray Structural Analysis for (CDCC 2309479).

The data presented this work results from the investigation on the pozzolanic activity and environmental impact of Portland cement CEM II produced with calcined slate waste (https://doi.org/10.1016/j.jobe.2024.110044). The data include information on the physical, chemical, and mineralogical characteristics of slate, as well as an indication of its pozzolanic activity. The dataset concerning the environmental impact assessment includes information on the processes of slate extraction, grinding, transportation, and calcination. Additionally, data on the inputs required for the production of 1 tonne of cement and the environmental impact for each studied impact category are provided., Summary Abstract 1 Value 2 Data Description 2.1 Technical assesment 2.2 Environmental assesment 3. Experimental design, materials and methods 3.1 Experimental design 3.2 Materials 3.3 Methods 3.3.1 X-ray diffraction test 3.3.2 X-ray fluorescence test 3.3.3 Loss of ignition test 3.3.4 Furier Transform Infrared Spectrophotometer test 3.3.5 Strength comparison method 3.3.6 Strength Activity Index comparison method 3.3.7 Frattini Test and Saturated lime test 3.3.8 Life cycle assesment 3.4 Equations used 3.4.1 Weight loss on ognition 3.4.2 Strength Activity Index 3.4.3 Frattini test and Saturated lime test 3.4.4 Calculation of the amount of mass to be calcined 3.4.5 Calcination energy calculation 4 References

There is vast amount of research that links implicit theories of intelligence with several learning-relevant variables in both learners and teachers alike. However, there is a gap in the literature, as there is almost no research done with university teachers. Furthermore, most scientific research polarizes incremental and fixed views of intelligence in spite of data that show there is heterogeneity in participants’ views. This study explores the implicit theories of intelligence of university teachers. The sample comprised 20 university teachers (10 men and 10 women) from the University of Seville. Four participants were selected from each field of knowledge, according to the category system in place at the university in question, namely: Arts and Humanities (A&H), Sciences (S), Health Sciences (HS), Social and Legal Sciences (S&LS), and Engineering and Architecture (E&A). Also, the selection process ensured that half the participants had less than 15 years' teaching experience at the university and the other half more than 15 years' experience. A semi-structured interview called "Views on Intelligence within the Educational Field" was designed. Participants were asked to express their opinión about several small vignettes regarding intelligence. The instrument comprises short cases or vignettes, highlighting different dimensions of intelligence. We identified 12 relevant dimensions in which a view on intelligence could be expressed and contextualized. They were: Control, Heredity, Effort, Culture, Training, Critical Period, Context, Expectations, Associated Qualities, People, Gender, and Diversity of Intelligence. Data from interviews were analysed employing a category system designed to capture heterogeneity. The utterances were segmented and analyzed using a coding manual. From the units of meaning extracted from the participant’s responses, we constructed 116 different categories related to intelligence. These categories were later organized into 18 different topics, as several themes arose from the interviews. These topics were: Effort, Genetic Influence, Development in Non-Specific Terms, Global Environment, Formal Education, Culture, Activities, Teacher Influence, Parental Influence, Developmental Characteristics, Motivational and Emotional Influence, Others’ Expectations Influence, Own Expectations Influence, Other Personal Characteristics Influence, Characteristics Associated to Intelligent People, Gender, Presence of Intelligence in Activities Outside Academic Fields, and Social and Emotional Intelligence. Finally, an upper-level hierarchical categorization was developed, where different categories were put together taking into account different criteria in order to obtain global results. These categories are Global Influences of Change (all categories that relate to modifiability of the intelligence), Specific Influences of Change (all categories that expresses the relation of something specific on intelligence), Non-Specific Influences of Change (all categories that expresses that intelligence can or cannot be modified, but not telling how), Individual Influences of Change (all categories related to the individual’s actions and characteristics linked to intelligence malleability), Environmental Influences of Change (all categories related to the environment that may or may not affect the development of intelligence), and Total Genetic Influence (all categories related to genetic influence)., - Base de Datos Concepciones de Inteligencia - Manual de Codificación Concepciones de Inteligencia

This dataset is part of a study that aims to analyze the energy performance of the residential building stock in the most populated city of Andalusia, Seville. The information contained in 45,920 energy performance certificates of dwellings was processed and analyzed according to the type of dwellings (single-family dwelling and individual dwellings in multi-family blocks), the period of construction and the district location. The results obtained in this study facilitate the identification of those districts and areas where the least efficient buildings are concentrated., Este conjunto de datos es parte de un estudio que presenta el análisis del comportamiento energético del parque de edificios residenciales construidos en la ciudad más poblada de Andalucía, Sevilla. Se procesaron los datos contenidos en 45.920 certificados de eficiencia energética de viviendas y se analizaron según su tipología (unifamiliares y viviendas individuales en bloques plurifamiliares), el periodo de construcción y el distrito donde se ubican. Los resultados obtenidos en este estudio permiten identificar aquellos distritos y zonas donde se concentran los edificios energéticamente menos eficientes., The dataset contains cartography generated from 45,920 energy performance certificates of Seville dwellings., El dataset contiene cartografía generada a partir de 45.920 certificados de eficiencia energética de viviendas de Sevilla.

Este dataset recolecta la formación inicial del contenido de agua y su distribución, así como la evacuación de agua, en una célula de combustible tipo PEM inspirada en un pulmón con un área activa de 50 cm2 para varias condiciones de operación como la presión de la célula, la humedad relativa (cátodo y ánodo), temperatura y densidad de corriente de la célula. Las imágenes por neutrones fueron empleadas ya que han demostrado ser una técnica efectiva para el análisis cuantitativo de la distribución del agua. Se presentan una serie de videos recolectando las imágenes individuales obtenidas a través de las imágenes de neutrones, mostrando la evolución de la distribución de agua. Se aporta una compilación numérica y gráfica de la cantidad de agua en una célula con el tiempo en distintas regiones de la célula para un total de 10 experimentos. La cantidad numérica de agua fue obtenida a partir del análisis y cálculos de las imágenes por neutrones obtenidas., exp_1234.mpeg, exp_5.mpeg, exp_678910.mpeg son vídeos creados a través de la unión de las imágenes por neutrones obtenidas para cada instante de tiempo estudiado, mostrando la evolución del contenido de agua con el tiempo. Corresponden a los experimentos 1-2-3-4, 5 y 6-7-8-9-10 respectivamente. Exp_transitional.pdf muestra las tablas y gráficas creadas a partir la cantidad de agua obtenida en las imágenes por neutrones para cada instante de tiempo para los 10 casos de experimentos. Hay una serie de gráficas agrupando todos los casos y casos similares, así como las gráficas que aparecen en el artículo en el que se basan.

This research project aims to measure and analyze the heterogeneity of university teachers’ conceptions of intelligence. To this end, we have developed a new method of analysis: Heterogeneity by Contradiction Analysis (HCA). We conducted semi-structured interviews with 20 university teachers, presenting them with a series of short cases or vignettes depicting different facets of intelligence. Based on the discourse elicited, we first created a category system. Then, we pre-defined a series of possible contradictions among pairs of categories. Using these pre-defined contradictions, a systematic sampling of theoretical contradictions could be obtained from the discourse. Finally, a researcher reviewed these sampled contradictions in order to find and code real contradictions, which were later analyzed., - Interview Script - Datos Heterogeneity - Manual de Codificación Concepciones de Inteligencia

This Phase 1b/2 study assessed the efficacy in terms of objective response rate (ORR) of the FGFR1/2/3 kinase inhibitor derazantinib as monotherapy or in combination with atezolizumab in patients with metastatic urothelial cancer (mUC) and FGFR1-3 genetic aberrations (FGFR1-3GA). This multicenter, open-label study comprised 5 substudies. In Substudies 1 and 5, patients with mUC with FGFR1-3GA received derazantinib monotherapy (300 mg QD in Substudy 1, 200 mg BID in Substudy 5). In Substudy 2, patients with any solid tumor received atezolizumab 1200 mg every 3 weeks plus derazantinib 200 or 300 mg QD. In Substudy 3, patients with mUC harboring FGFR1-3GA received derazantinib 200 mg BID plus atezolizumab 1200 mg every 3 weeks. In Substudy 4, patients with FGFR inhibitor-resistant mUC harboring FGFR1-3GA received derazantinib 300 mg QD monotherapy or derazantinib 300 mg QD plus atezolizumab 1200 mg every 3 weeks. The ORR for Substudies 1 and 5 combined was 4/49 (8.2%, 95% confidence interval = 2.3% to 19.6%), which was based on 4 partial responses. The ORR in Substudy 4 was 1/7 (14.3%, 95% confidence interval = 0.4% to 57.9%; 1 partial response for derazantinib 300 mg monotherapy, zero for derazantinib 300 mg plus atezolizumab 1200 mg). In Substudy 2, derazantinib 300 mg plus atezolizumab 1200 mg was identified as a recommended dose for Phase 2. Only 2 patients entered Substudy 3. Derazantinib as monotherapy or in combination with atezolizumab was well-tolerated but did not show sufficient efficacy to warrant further development in mUC. Clinicaltrials.gov NCT04045613, EudraCT 2019-000359-15.

Diffuse large B cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma worldwide. DLBCL is an aggressive disease that can be cured with upfront standard chemoimmunotherapy schedules. However, in approximately 35-40% of the patients DLBCL relapses, and therefore, especially in this setting, the search for new prognostic and predictive biomarkers is an urgent need. Natural killer (NK) are effector cells characterized by playing an important role in antitumor immunity due to their cytotoxic capacity and a subset of circulating NK that express CD8 have a higher cytotoxic function. In this substudy of the R2-GDP-GOTEL trial, we have evaluated blood CD8+ NK cells as a predictor of treatment response and survival in relapsed/refractory (R/R) DLBCL patients. 78 patients received the R2-GDP schedule in the phase II trial. Blood samples were analyzed by flow cytometry. Statistical analyses were carried out in order to identify the prognostic potential of CD8+ NKs at baseline in R/R DLBCL patients. Our results showed that the number of circulating CD8+ NKs in R/R DLBCL patients were lower than in healthy donors, and it did not change during and after treatment. Nevertheless, the level of blood CD8+ NKs at baseline was associated with complete responses in patients with R/R DLBCL. In addition, we also demonstrated that CD8+ NKs levels have potential prognostic value in terms of overall survival in R/R DLBCL patients. CD8+ NKs represent a new biomarker with prediction and prognosis potential to be considered in the clinical management of patients with R/R DLBCL. https://www.clinicaltrialsregister.eu/ctr-search/search?query=2014-001620-29 EudraCT, ID:2014-001620-29., Si