Resultados de investigación

The potassium–chloride cotransporter KCC2 is the main extruder of Cl- in neurons. It plays a fundamental role in the activity of the inhibitory neurotransmitters (GABA and glycine) since low levels of KCC2 promote intracellular Cl- accumulation, leading to the depolarizing activity of GABA and glycine. The downregulation of this cotransporter occurs in neurological disorders characterized by hyperexcitability, such as epilepsy, neuropathic pain, and spasticity. KCC2 is also downregulated after axotomy. If muscle reinnervation is allowed, the KCC2 levels recover in motoneurons. Therefore, we argued that target-derived neurotrophic factors might be involved in the regulation of KCC2 expression. For this purpose, we performed the axotomy of extraocular motoneurons via the monocular enucleation of adult rats, and a pellet containing either VEGF or BDNF was chronically implanted in the orbit. Double confocal immunofluorescence of choline acetyl-transferase (ChAT) and KCC2 was carried out in the brainstem sections. Axotomy led to a KCC2 decrease in the neuropil and somata of extraocular motoneurons, peaking at 15 days post-lesion, with the exception of the abducens motoneuron somata. VEGF administration prevented the axotomy-induced KCC2 downregulation. By contrast, BDNF either maintained or reduced the KCC2 levels following axotomy, suggesting that BDNF is involved in the axotomy-induced KCC2 downregulation in extraocular motoneurons. The finding that VEGF prevents KCC2 decrease opens up new possibilities for the treatment of neurological disorders coursing with neuronal hyperactivity due to KCC2 downregulation.

The dataset contains the X-ray difraction patterns of (1-x)BaZr0.2Ti0.8O3–(x)Ba0.7Ca0.3TiO3 solid solution powder obtained by mechanosynthesis (x = 0.4, 0.45, 0.5, 0.55, and 0.6). It also includes patterns of thermally treated powder and fine-grained related ceramics densified by conventional in atmospheric air and hot-press sintering. The dataset is part of research funded by: Grant Agency: MICIU/AEI/ 10.13039/501100011033 and “European Union NextGenerationEU/PRTR” Grant Number: TED2021-131458A-I00 Grant Agency: MICIU/AEI/10.13039/501100011033 Grant Number: PID2020-117648RB-I00, File name: BCZT-04.ASC. Description: X-ray difraction pattern of as-milled Ba0.88Ca0.12Zr0.12Ti0.88O3 (powder form) File name: BCZT-045.ASC. Description: X-ray difraction pattern of as-milled Ba0.865Ca0.135Zr0.11Ti0.89O3 (powder form) File name: BCZT-05.ASC. Description: X-ray difraction pattern of as-milled Ba0.85Ca0.15Zr0.1Ti0.9O3 (powder form) File name: BCZT-055.ASC. Description: X-ray difraction pattern of as-milled Ba0.835Ca0.165Zr0.09Ti0.91O3 (powder form) File name: BCZT-06.ASC. Description: X-ray difraction pattern of as-milled Ba0.82Ca0.18Zr0.08Ti0.92O3 (powder form) File name: 900-BCZT-04.ASC. Description: X-ray difraction pattern of Ba0.88Ca0.12Zr0.12Ti0.88O3 (powder form) annealed at 900 °C/1 h File name: 900-BCZT-045.ASC. Description: X-ray difraction pattern of Ba0.865Ca0.135Zr0.11Ti0.89O3 (powder form) annealed at 900 °C/1 h File name: 900-BCZT-05.ASC. Description: X-ray difraction pattern of Ba0.85Ca0.15Zr0.1Ti0.9O3 (powder form) annealed at at 900 °C/1 h File name: 900-BCZT-055.ASC. Description: X-ray difraction pattern of Ba0.835Ca0.165Zr0.09Ti0.91O3 (powder form) annealed at at 900 °C/1 h File name: 900-BCZT-06.ASC. Description: X-ray difraction pattern of Ba0.82Ca0.18Zr0.08Ti0.92O3 (powder form) annealed at at 900 °C/1 h File name: CS-BCZT-04.ASC. Description: X-ray difraction pattern of Ba0.88Ca0.12Zr0.12Ti0.88O3 conventionally sintered at 1450 °C/4 h in atmospheric air File name: CS-BCZT-045.ASC. Description: X-ray difraction pattern of Ba0.865Ca0.135Zr0.11Ti0.89O3 conventionally sintered at 1450 °C/4 h in atmospheric air File name: CS-BCZT-05.ASC. Description: X-ray difraction pattern of Ba0.85Ca0.15Zr0.1Ti0.9O3 conventionally sintered at 1450 °C/4 h in atmospheric air File name: CS-BCZT-055.ASC. Description: X-ray difraction pattern of Ba0.835Ca0.165Zr0.09Ti0.91O3 conventionally sintered at 1450 °C/4 h in atmospheric air File name: CS-BCZT-06.ASC. Description: X-ray difraction pattern of Ba0.82Ca0.18Zr0.08Ti0.92O3 conventionally sintered at 1450 °C/4 h in atmospheric air File name: HP-BCZT-04.ASC. Description: X-ray difraction pattern of Ba0.88Ca0.12Zr0.12Ti0.88O3 sintered by hot-pressing at 1400 °C/4 h in vacuum File name: HP-BCZT-045.ASC. Description: X-ray difraction pattern of Ba0.865Ca0.135Zr0.11Ti0.89O3 sintered by hot-pressing at 1400 °C/4 h in vacuum File name: HP-BCZT-05.ASC. Description: X-ray difraction pattern of Ba0.85Ca0.15Zr0.1Ti0.9O3 sintered by hot-pressing at 1400 °C/4 h in vacuum File name: HP-BCZT-055.ASC. Description: X-ray difraction pattern of Ba0.835Ca0.165Zr0.09Ti0.91O3 sintered by hot-pressing at 1400 °C/4 h in vacuum File name: HP-BCZT-06.ASC. Description: X-ray difraction pattern of Ba0.82Ca0.18Zr0.08Ti0.92O3 sintered by hot-pressing at 1400 °C/4 h in vacuum

Primera cita de Neofusicoccum parvum y N. australe en España como agentes patógenos produciendo chancros en plantas de arándano de la provincia de Huelva. Se hizo una identificación morfológica y molecular de los aislados encontrados y se confirmó la patogenicidad de dichos aislados con un ensayo cumpliendo los postulados de Koch.

La base de datos recoge los ítems de los constructos implicados en el modelo de investigación del artículo asociado. Los datos fueron recogidos en 2019 para visitantes de la ciudad de Coimbra (Portugal). En la pestaña Series se describen los ítems de los constructos. En la pestaña DATOS, están recogido los datos de los indicadores correspondientes al año 2019. El modelo de investigación permite identificar la influencia de la motivación cognitiva y afectiva, la autenticidad percibida (objetiva y existencia), la imagen del destino sobre la intención de comportamiento.

Psychological memory tests have traditionally relied on paper-based methods. However, the emergence of virtual reality tools, including adaptations of animal lab tests, has opened up new possibilities for evaluating and enhancing attention and memory processes. The impact of virtual environments on spatial memory remains a topic of ongoing debate. To contribute to this discussion, we conducted a comprehensive study with two primary objectives. Firstly, we aimed to develop a virtual reality tool that could effectively assess search strategies in gamers within virtual environments. To achieve this, we designed a virtual water maze inspired by those used in animal research. Secondly, we conducted a cross-sectional study involving participants to analyze how spatial memory strategies evolve in a virtual environment with increasing gaming experience. The results revealed that participants with more gaming experience exhibited faster and more precise learning in the virtual water maze, along with improved search strategies. Additionally, our study allowed for the evaluation of our software and enabled us to track changes in the efficacy of learning strategies. Overall, this study emphasizes the potential of virtual environments for both evaluation and cognitive stimulation purposes, ID, Gamer type, Scenes types, First assessment (s), Second assessment (s)

Esta base de datos contiene los datos empleados en el artículo "El efecto del altruismo en las tasas de vacunación contra la COVID-19". Los datos abarcan a los países de la Unión Europea. La base de datos está conformada por cuatro secciones. En la primera sección se incluyen los datos finales referidos a las variables empleadas en el estudio. En la segunda sección se incluyen los datos sobre vacunación total sin transformar, mientras que en la sección tercera y cuarta se incluyen los datos trasformados a través de interpolación lineal para obtener series completas del nivel de vacunación total y en porcentaje sobre la población, respectivamente., - Hoja 1: Datos finales empleados en el estudio. - Hoja 2: Datos originales sobre vacunación total por países. - Hoja 3: Datos trasformados por interpolación lineal sobre vacunación total por países. - Hoja 4: Datos trasformados por interpolación lineal sobre porcentaje de vacunación sobre población por países., Premio Trimestral Publicación Científica Destacada de la US. Facultad de Ciencias Económicas y Empresariales

Los datos de la base de datos permiten calcular los scores de eficiencia de cada destino turístico. Asimismo, también permite realizar el análisis de regresión para identificar qué pilares tiene influencia significativa en dicha eficiencia. El contenido del dataset está organizado en pestañas o “taps”. En la pestaña SERIES aparece la descripción de los pilares del Índice de Desarrollo de Viajes y Turismo (TTDI) elaborado por World Econimc Forum (WEF) (edición 2019) e indicadores de eficacia (año 2019): International tourism receipts (inbound US$, millions) Average spending per int'l tourist (US$) T&T industry GDP (US$ million) T&T industry Employment (1,000 jobs) T&T industry Share of GDP (% of total GDP) T&T industry Share of Employment (% of total employment) En la pestaña DATOS, están recogido los datos de los indicadores correspondientes al año 2019

Datasets pertain to a study on the effect of the ungulate community composition on short distance seeds dispersal and the potential generation of spatial pattern of plant species distribution. The study was conducted at two grassland sites (Martinazo and Matasgordas) in the Doñana National Park (SW Spain). The sites were used by: i) a four ungulate species comunity (i.e., deer, wild boar, cattle and horse) and ii) a community highly dominated by deer. Both sites differed in the total number of herbaceous seeds dispersed and in the plant families most abundantly dispersed. In the four-species ungulate community, cow and deer were the most dissimilar pair in taxonomic composition of dispersed seeds. In addition, in this community, but not in the deer dominated one, we found significant spatial patterns of total seed dispersal (significant positive effect of short-distance feces aggregation, spatial covariance in seed content of two nearby feces, and significant correlation between seed content and density of nearby feces) as well as significant spatial pattern of dispersal of the seeds families preferentially associated with cow. These findings highlight a notable effect of the composition of disperser community on seeds dispersal and spatial structure at the short spatial scale of this study Dataset consists of ten datafiles that include: i) information on seed content and taxonomic composition (families) in fecal samples collected in the two study sites (Matasgordas and Martinazo) and where the ungulate comunities are composed by a single disperser (deer in Matasgordas) or four dispersers (dear, cow, horse, wild board in Martinazo) and ii) information on spatial coordinates of fecal samples collected in the two sites (Martinazo and Matasgordas) as well as the seed content per sample (total seed content and seed content of the three most frequent plant families dispersed at each site)., Two files include data on seeds content and taxonomic composition in the feces from deer occurring in the two study sites (file #1) and on seeds content and taxonomic composition in feces from the four ungulates occurring in Martinazo site (file #2). Other eight files include information on spatial coordinates of fecal samples collected in the two sites (Martinazo and Matasgordas) as well as the seed content per sample (total seed content and seed content of the three most frequent plant families dispersed at each site). (files #3 to 10).

The identification phase, in accordance with the PRISMA 2020 guidelines, requires specifying the databases consulted and the exact strategy used to locate studies. The Web of Science (WoS) database was selected to conduct this review. Specifically, only the WoS Core Collection (SSCI and SCI-Expanded) was targeted to guarantee that all included empirical studies had surpassed the most rigorous indexing standards of the Journal Citation Reports (JCR)—uniquely relevant to the Management and Computer Science areas addressed in this research—thereby ensuring the maximum methodological quality of the audited evidence. This delimitation was adopted to restrict the scope to a database of maximum rigor. When performing the document search, the following keyword sequence was utilized in the search engine: (“Artificial Intelligence”) AND (“Recruitment”). This combination was used as a Boolean indexing root within the Topic fields, as the granularity of sub-terms (NLP, LLM, Neural Networks) was naturally absorbed due to the high cross-indexing of WoS. These two terms were chosen as root macro-concepts precisely to prioritize the specificity of thematic matching in high-level management fields, avoiding the noise of pure engineering terms alien to HR. Following the search, executed on January 20, 2026, a total of 438 initial records were obtained, establishing December 31, 2025, as the inclusion deadline. However, with the purpose of obtaining a sample of recent, thematic, and fully accessible literature for complete review, the following search and selection criteria were applied directly within the platform: - Access filter: Results were restricted to Open Access publications. This filter was applied under the principles of Open Science, given that AI research applied to human resources is heavily published in open repositories due to the speed of technological transfer and to ensure full access, auditability, and reproducibility of the sample by the scientific community, accepting any coverage limitations this might imply; the combination of the WoS Core Collection with the Open Access filter guaranteed that the final sample was auditable, reproducible, and of high normative impact, minimizing the influence of grey literature. - Temporal filter: The analysis period was defined for articles published or indexed up to December 2025. - Document types: Research articles were exclusively selected (Article). - Language filter: The search was configured to include only publications in English, thus guaranteeing the linguistic homogeneity of the analysis. - Knowledge area filter: Categories closely aligned with this study were exclusively selected (Business Economics, Engineering, Computer Science, Physiology [due to the potential use of biometrics, facial expression recognition, or neuroscience], and Social Sciences Other Topics), discarding any scientific discipline unrelated to the purpose of the research.

This dataset contains participant-level tabular data from a clinical study on ocular surface/dry eye outcomes, including demographic variables and repeated measures collected at baseline (B), 3 months (3M), and 6 months (6M). Variables include OSDI questionnaire scores, non-invasive tear break-up time (NIBUT), Schirmer test values (ST), and additional derived change-score variables computed by the study team.