Resultados de investigación

Breast cancer (BC), despite its high survival rate, can lead to significant functional sequelae in the glenohumeral joint following surgical intervention. The present study explores the possible influence of the operated side on angular velocity during a lateral opening test, comparing the intervened arm with the non-operated arm, as a potential indicator of functional asymmetry. This is an observational study with a comparative cross-sectional design. The sample consisted of 22 women, with a mean age of 55.95 ± 6.34 years, who were BC survivors and had undergone surgery on only one arm. Angular velocity was recorded in both arms at 1000 Hz for 15 repetitions on an inclined bench with a 2 kg load, using the WIMU PRO™ inertial device. The results, analyzed using repeated measures ANOVA, showed a significant interaction between the evaluated arm and the operated side (p = 0.001), suggesting lower velocity in the affected arm. This difference could indicate the existence of postoperative functional asymmetries, which would have relevant implications for the prescription of individualized therapeutic exercise. The use of angular velocity as a complementary tool for functional assessment in rehabilitation programs for BC survivors is suggested.

Glioblastoma (GB) is one of the most aggressive and treatment-resistant cancers due to its complex tumor microenvironment (TME). We previously showed that GB progression is dependent on the aberrant induction of chaperone-mediated autophagy (CMA) in pericytes (PCs), which promotes TME immunosuppression through the PC secretome

The increasing presence of extremely low-frequency electromagnetic fields (ELF-EMF) in marine environments, driven by human activities and climate change, poses a potential risk to aquatic organisms. This study investigated the physiological and immunological effects of ELF-EMF exposure on gilthead seabream (Sparus aurata), a key species in Mediterranean aquaculture. Fish were exposed to ELF-EMF for one or three weeks, and their growth, serum immune parameters (peroxidase and lysozyme activities), and tissue chemical elements were compared with those of unexposed controls. No significant differences were observed in fish weight, length, or serum immune parameters between the exposed and control groups at any time point. However, a significant reduction in liver cadmium (Cd) levels was detected in fish exposed to ELF-EMF for three weeks, suggesting potential modulation of metal detoxification pathways. The concentrations of other elements, including arsenic (As), lead (Pb), iron (Fe), manganese (Mn), copper (Cu), and zinc (Zn), showed minor changes in various tissues. The levels of sodium (Na), magnesium (Mg), calcium (Ca), and potassium (K) were altered in some tissues after one week of ELF-EMF exposure but generally returned to control levels after three weeks. These findings indicate that short-term ELF-EMF exposure does not significantly affect growth or innate immunity in gilthead seabream under the tested conditions. The observed alterations in tissue levels of toxic and trace elements, as well as macronutrients, indicate potential interactions between ELF-EMF, metal homeostasis, and detoxification mechanisms, necessitating further investigation. This study contributes to the understanding of the effects of anthropogenic ELF-EMF on marine organisms and highlights the need for continued research to assess the long-term ecological implications of increasing ELF-EMF levels in aquatic environments.

La base de datos se integra en el proyecto de investigación PID2022-136372NB, “Liderazgo Institucional para la Evaluación de las Competencias de los Estudiantes y el Desarrollo del Engagement Universitario-LIECEDEU, financiado por la Agencia Española de Investigación, el Ministerio de Ciencia, Innovación y Universidades y cofinanciado por la Unión Europea. Se han seguido las directrices de la declaración PRISMA 2020 (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) (Page et al., 2021). Este enfoque metodológico permite identificar, seleccionar y analizar de manera transparente y replicable los estudios relevantes sobre un tema específico. La revisión se centró en la producción científica publicada entre 2015 y 2024 relacionada con la evaluación del aprendizaje en educación superior, el engagement del alumnado universitario y la relación entre ambos constructos, prestando especial atención a la incorporación de la perspectiva del alumnado en dichas investigaciones. La búsqueda de publicaciones se centró en dos bases de datos: Web of Science y Dialnet, seleccionadas por su relevancia en el ámbito de las ciencias de la educación y por su cobertura de publicaciones internacionales y del contexto iberoamericano.