BUSCADOR RECOLECTA

This dataset collects 1,433 bibliographic references related to Spanish architecture during the Franco's dictatorship (1939-1975). The research was focused on news of Spanish Architecture abroad, including academic journals, architectural press, conference proceedings, books, book chapters, magazines and newspapers, but it excludes the Spanish media. All references were tagged including names of architects, buildings, types of buildings and cities. The database is delivered in three file formats (BibTeX, RIS and Zotero RDF), which are compatible with several reference managers as Zotero, Mendeley, EndNote or RefWorks. This dataset was produced by the R&D project “Spanish architecture in international communication media: Publications, exhibitions, congresses (First part: 1940-1975)”. Three ways were used to find the news: Firstly, systematic research was done using architectural databases as Avery Index to Architectural Periodicals, JSTOR or ProQuest Periodicals Index Online; secondly, the most influential architectural magazines were revised in paper (The Architectural Review, Architectural Forum, Casabella continuità, Domus or L’Architecture d’Aujourd’hui); and thirdly, some authors and works were studied following bibliographical references published in their monographs.

These data are associated to the paper with the same title of the authors, and are structured according to the figures in the paper: http://hdl.handle.net/2117/335727, The use of Cold Atmospheric Plasma (CAP) in oncology is being recently studied as a novel potential anti-cancer therapy. However, the beneficial effects of CAP for treating osteosarcoma have mostly been demonstrated in 2-dimensional cultures of cells, which do not mimic the complexity of the 3-dimensional (3D) bone microenvironment. In order to evaluate the effects of CAP in a relevant context of the human disease, we developed a 3D tissue-engineered model of osteosarcoma using a bone-like scaffold made of collagen type I and hydroxyapatite nanoparticles. Human osteosarcoma cells cultured within the scaffold showed a high capacity to infiltrate and proliferate and to exhibit osteomimicry in vitro. As expected, we observed significantly different functional behaviors between monolayer and 3D cultures when treated with Cold Plasma-Activated Ringer’s Solution (PAR). Our data reveal that the 3D environment not only protects cells from PAR-induced lethality by scavenging and diminishing the amount of reactive oxygen and nitrogen species generated by CAP, but also favours the stemness phenotype of osteosarcoma cells. This is the first study that demonstrates the negative effect of PAR on cancer stem-like cell subpopulations in a 3D biomimetic model of cancer. These findings will allow to suitably re-focus research on plasma-based therapies in future