BUSCADOR RECOLECTA

To investigate the safety and immunogenicity of a modified vaccinia virus Ankara vector expressing HIV-1 antigens from clade B (MVA-B), a phase-I, doubled-blind placebo-controlled trial was performed., Peer reviewed

Attenuated poxvirus vectors expressing human immunodeficiency virus type 1 (HIV-1) antigens are considered promising HIV/AIDS vaccine candidates. Here, we describe the nature of T cell immune responses induced in healthy volunteers participating in a phase I clinical trial in Spain after intramuscular administration of three doses of the recombinant MVA-B-expressing monomeric gp120 and the fused Gag-Pol-Nef (GPN) polyprotein of clade B. The majority (92.3%) of the volunteers immunized had a positive specific T cell response at any time postvaccination as detected by gamma interferon (IFN-γ) intracellular cytokine staining (ICS) assay. The CD4(+) T cell responses were predominantly Env directed, whereas the CD8(+) T cell responses were similarly distributed against Env, Gag, and GPN. The proportion of responders after two doses of MVA-B was similar to that obtained after the third dose of MVA-B vaccination, and the responses were sustained (84.6% at week 48). Vaccine-induced CD8(+) T cells to HIV-1 antigens after 1 year were polyfunctional and distributed mainly within the effector memory (TEM) and terminally differentiated effector memory (TEMRA) T cell populations. Antivector T cell responses were mostly induced by CD8(+) T cells, highly polyfunctional, and of TEMRA phenotype. These findings demonstrate that the poxvirus MVA-B vaccine candidate given alone is highly immunogenic, inducing broad, polyfunctional, and long-lasting CD4 and CD8 T cell responses to HIV-1 antigens, with preference for TEM. Thus, on the basis of the immune profile of MVA-B in humans, this immunogen can be considered a promising HIV/AIDS vaccine candidate., Peer reviewed

Audiovisual sobre el grupo artístico 4 Elementes, autores de Postlibros, Peer reviewed

Especial del programa "Fora d'hores" de Ràdio 4 produït pel "Laboratori de Produccions Sonores de Ficció i Entreteniment" de la Llicenciatura de Comunicació Audiovisual de la UAB, Presentació: M.Antònia Suau, Emès el dia 12 de desembre de 2004, Duració: 005539

Especial del programa "Fora d'hores" de Ràdio 4 produït pel "Laboratori de Produccions Sonores de Ficció i Entreteniment" de la Llicenciatura de Comunicació Audiovisual de la UAB, Presentació: Robert Marsé, Duració: 005544

8 programes especials del programa "Fora d'hores" de Ràdio 4 produït pel "Laboratori de Produccions Sonores de Ficció i Entreteniment" de la Llicenciatura de Comunicació Audiovisual de la UAB, Emesos entre el juny i el setembre de 2011

File "table1.dat" contains the CIG number, and general data for the total CO sample., File "tale4.dat" contains the CIG number, and the velocity integrated 12CO(1-0) intensities, line width and central velocities for galaxies newly observed., File "tale5.dat" contains the CIG number and the molecular gas mass for the total CO sample., We characterize the molecular gas content (ISM cold phase) using CO emission of a redshift-limited subsample of isolated galaxies from the AMIGA (Analysis of the interstellar Medium of Isolated GAlaxies) project in order to provide a comparison sample for studies of galaxies in different environments. We present the ^12^CO(1-0) data for 273 AMIGA galaxies, most of them (n=186) from our own observations with the IRAM 30m and the FCRAO 14m telescopes and the rest from the literature. We constructed a redshift-limited sample containing galaxies with 1500km/s

Open data and code for main analyses in "A test-retest assessment of the effects of mental load on ratings of affect, arousal and perceived exertion during submaximal cycling".

Attached you can find the complementary dataset about phytoplankton functional groups. We referred to these data in the manuscript "Do magnetic phosphorus adsorbents used for lake restoration impact on zooplankton community?" submitted for publication in Water Resources Research

Dataset of the paper "On the need of a unified methodology for processing Schumann resonance measurements" published in JGR Atmospheres.