BUSCADOR RECOLECTA

[Description of methods used for collection/generation of data] Field measurements of P- and S-wave velocities using a Monolith A1220 Velocity Tester., Multiparamatetric petrophysical dataset of experimental measurments on borehole samples from Collinstown (Ireland). Contains measurements of Vp, Vs, density, resistivity, chargeability and magnetic susceptibility., VECTOR., Peer reviewed

Description of methods used for collection/generation of data] field measurements of P- and S-wave velocities using a Monolith A1220 Velocity Tester; and SM-20 susceptibility meter., Multiparamatetric petrophysical dataset of experimental measurments on borehole samples from the Spremberg (Germany). Contains measurements of Vp, Vs and Magnetic susceptibility., VECTOR., Peer reviewed

Database containing raw analytical data obtained in the SEROCOV-1 study and personal covariates used by Ortega-Ribes et al. (Nature Communications, 2021). Data correspond to antibody levels to SARS-CoV-2 and four seasonal coronaviruses, and the neutralization capacity of 578 participants recruited from 28 March- 9 April 2020, and the follow-up visits after one, three and six months. The analytical data is completed with participants' information on occupation, comorbidities, previous COVID19 diagnoses and other sociodemographic characteristics. The code was developed using R version 4.0.3.

This database contains data from saliva samples from children who have participated in the study "Replication Antibody Conversion rates to SARS-CoV-2 in Saliva from Children Attending Summer Schools in Barcelona, Spain". Data come from 1,509 children and 396 adults by high-throughput Luminex assays in samples collected weekly in 22 Summer schools and 2 pre-schools in 27 venues in Barcelona, Spain, from June 29th to July 31st 2020. Saliva samples were collected for each participant on two visits 5 weeks apart. IgM, IgA and IgG values have been obtained from each sample to detect SARS-CoV-2

Dades primàries associades a l'article publicat a BMC Pediatrics, vol. 17 [https://doi.org/10.1186/s12887-017-0816-x], Background: Young children bear the world’s highest prevalence of anaemia, the majority of which is of multifactorial aetiology, which in turn hampers its successful prevention. Even moderate degrees of anaemia are associated with increased mortality and morbidity. Despite this evidence, there is a lack of effective preventive programs and absence of consensus in the safety of iron supplementation in malaria areas, which reflects the poor understanding of the contribution of different aetiologies to anaemia. In order to reduce the anaemia burden in the most vulnerable population, a study to determine the aetiology of anaemia among pre-school Mozambican children was performed. Methods: We undertook a case-control study of 443 preschool hospitalized children with anaemia (haemoglobin concentration <11g/dl) and 289 community controls without anaemia. Inclusion criteria were: age 1-59 months, no blood transfusion in the previous month, residence in the study area and signed informed consent. Both univariable and multivariable logistic regression analyses were performed to identify factors associated with anaemia and adjusted attributable fractions (AAF) were estimated when appropriate. Results: Malaria (adjusted odds ratio (AOR)=8.39, p<0.0001; AAF=37%), underweight (AOR=8.10, p<0.0001; AAF=43%), prealbumin deficiency (AOR=7.11, p<0.0001; AAF=77%), albumin deficiency (AOR=4.29, p=0.0012; AAF=30%), HIV (AOR=5.73, p=0.0060; AAF=18%), and iron deficiency (AOR=4.05, p<0.0001; AAF=53%) were associated with anaemia. Vitamin A deficiency and α-thalassaemia were frequent (69% and 64%, respectively in cases) but not independently related to anaemia. Bacteraemia (odds ratio (OR)=8.49, p=0.004), Parvovirus-B19 (OR=6.05, p=0.017) and Epstein-Barr virus (OR=2.10, p=0.0015) infections were related to anaemia only in the unadjusted analysis. Neither vitamin B12 deficiency nor intestinal parasites were associated with anaemia. Folate deficiency was not observed. Conclusions: Undernutrition, iron deficiency, malaria, and HIV are main factors related to anaemia in hospitalised Mozambican preschool children. Effective programs and strategies for the prevention and management of these conditions need to be reinforced. Specifically, prevention of iron deficiency that accounted in this study for more than half of anaemia cases would have a high impact in reducing the burden of anaemia in children living under similar conditions. However this deficiency, a common preventable and treatable condition, remains neglected by the international public health community.

Study of immune correlates against malaria after vaccination with RTS,S/ASO1E: a comphrensive immunological arm of a Phase III double-blind, randomize, controlled multi-centre trial (MAL067)., Dades primàries associades a l'article publicat a NPJ Vaccines, vol. 5 [https://doi.org/10.1038/s41541-020-0192-7], The RTS,S/AS01E vaccine has shown consistent but partial vaccine efficacy in a pediatric phase 3 26 clinical trial using a 3-dose immunization schedule. A fourth dose 18 months after the primary 27 vaccination was shown to restore the waning efficacy. However, only total IgG against the 28 immunodominant malaria vaccine epitope has been analyzed following the booster. To better 29 characterize the magnitude, nature and longevity of the immune response to the booster, we 30 measured levels of total IgM, IgG and IgG1-4 subclasses against three constructs of the 31 circumsporozoite protein (CSP) and the hepatitis B surface antigen (HBsAg, also present in RTS,S) 32 by quantitative suspension array technology in 50 subjects in the phase 3 trial in Manhiça, 33 Mozambique. To explore the impact of vaccination on naturally acquired immune responses, we 34 measured antibodies to P. falciparum antigens not included in RTS,S. We found increased IgG, 35 IgG1, IgG3 and IgG4, but not IgG2 nor IgM, levels against vaccine antigens one month after the 4th 36 dose. Overall, antibody responses to the booster dose were lower than the initial peak 37 response to primary immunization and children had higher IgG and IgG1 levels than infants. 38 Higher anti-Rh5 IgG and IgG1-4 levels were detected after the booster dose, suggesting that RTS,S 39 partial protection could increase some blood stage antibody responses. Our work shows that the 40 response to the RTS,S/AS01E booster dose is different from the primary vaccine immune 41 response and highlights the dynamic changes in subclass antibody patterns upon the vaccine 42 booster and with acquisition of adaptive immunity to malaria.

The data acquisition contract was funded by the "Programa estatal de fomento de la investigación científica y técnica de excelencia-subprograma estatal de generación de conocimiento" of the Ministry of economy and competitiveness and took place in 2015. Seismic data was successfully collected in Alhama de Murcia (Spain). The total amount of seismic reflection data collected was 13.2 km in 6 profiles NW-SE oriented. Technical specifications of the profiles: Receiver number: 240, Receiver interval: 2 m, Source: accelerated weightdrop 250 kg, Source interval: 6 m, Sample rate: 1 ms, Record time: 4 s. Contact people: Martínez-Díaz, J.; jmdiaz@geo.ucm.es and Carbonell, R.; rcarbo@ictja.csic.es, This work is part of the research project: “InterGeo”. One of the main objectives of this project is to understand the seismogenetic behavior of the Alhama de Murcia Fault (FAM) located in the Betic Cordillera (Spain). In this study several intersegment areas were defined. Some structural and paleoseismic studies and geophysical surveys have been carried out on these zones., Research project reference code: CGL2013-47412-C2-1-P, Peer reviewed

The acquired data comprises 2D/3D and 3C components. The acquisition employed 647 seismic receivers, distributed in a 3D mesh around the target and along six 2D crooked lines sampling the study area. The source employed was a 32 t vibroseis truck, operating at c. 900 points in the pathways along the 2D profiles. Each vibration point was used three times, with frequency sweeps of 10-100 Hz., Fair and sustainable production of raw materials is one of the main challenges faced by our society. Through its RawMaterials Programme, the European Institute of Technology (EIT) encourages research and innovation solutions for mineral exploration to make them safer, sustainable and cost-effective. The SIT4ME project, funded by EIT, addresses these objectives by undertaking seismic mineral exploration methods in crystalline tectonic settings, at a reduced cost. The SIT4Me project will analyse the efficiency of passive seismic methods (i.e. ambient noise interferometry) for subsurface imaging, by comparing active- and passive-source datasets in mining areas. The files in this dataset correspond to the controlled-source acquisition., European Institute of Innovation & Technology, Grant number EIT 17024, SIT4ME project, Peer reviewed

The data acquisition contract was awarded to ENRESA and took place in November and December 2013. Seismic data was successfully collected in the Záncara river basin (Cuenca, Spain). The total amount of seismic reflection data collected was 9.7 km in 4 high-resolution seismic reflection profiles E-W oriented. Technical specifications of the profiles: Seismometer: 10 24-channel GEODE ultra-light seismic recordes, Receiver number: 240, Receiver interval: 2 m, Source: accelerated weightdrop 250 kg and 100 kg, Source interval: 6 m, Sample rate: 1 ms, Record time: 4 s. Contact person: Carbonell, R., rcarbo@ictja.csic.es, A high-resolution 2-D seismic reflection survey was acquired to obtain a seismic image of the geological structure of the Záncara river basin (eastern Spain). The study area consists of lutites and gypsum from a Neogene sedimentary sequence. The project also targeted the geometry of the geological structure and the mechanical properties of the underground materials. In addition, this study allowed for an improvement of the geophysical acquisition technics and protocols that provided with a better resolution seismic imaging. Thus, reducing costs and improving the effectiveness of the seismic acquisition., Convenio Colaboración CSIC-ENRESA. Código CSIC: 20133830, Peer reviewed

The data acquisition contract was awarded to ENRESA and took place in January 2014. Seismic data was successfully collected in the Záncara river basin (Cuenca, Spain). This is a high-resolution seismic tomography survey to obtain a full 3-D P-wave seismic velocity image of the studied area. A regular and dense grid of 676 shots and 1200 receivers was used to image a 500 m x 500 m area of the shallow surface. A 240-channel system and a seismic source, consisting of an accelerated weight drop, were used in the acquisition. Half a million travel-time picks were inverted to provide the 3-D seismic velocity distribution up to 120 m depth. The 3-D survey was acquired in five swaths, each one consisting on five receiver lines, resulting in a total of 3380 shot gathers. Technical specifications of the profiles: Receiver number: 240, Receiver interval: 2 m, Source accelerated weightdrop: 250 kg, Source interval: 6 m, Sample rate: 1 ms, Record time: 4 s., In this repository, in addition to the seismic 3DSurvey, a resistivity model (VICANAS_3D_Res_UTM30), a lithological model (VICANAS_3D_Vp_Res_Lito_UTM30), and a training set (VICANAS_Training_set) are available. In order to improve the geological interpretation of the seismic tomography, we integrated it with the resistivity model to build a 3D lithological model. To this aim, we created a new bi-parameter grid with Vp and Res values at each node. Then, we lithologically classified the nodes using supervised learning according to a training set extracted from the wells., A high-resolution seismic tomography survey was acquired to obtain a full 3-D P-wave seismic velocity image of the Záncara river basin (eastern Spain). The study area consists of lutites and gypsum from a Neogene sedimentary sequence. The project also targeted the geometry of the underground structure with emphasis on defining the lithological contacts but also the presence of cavities and faults or fractures. An extensive drilling campaign provided uniquely tight constraints on the lithology; these included core samples and wireline geophysical measurements. The analysis of the well log data enabled the accurate definition of the lithological boundaries and provided an estimate of the seismic velocity ranges associated with each lithology. The final joint interpreted image reveals a wedge-shaped structure consisting of four different lithological units. The study features the necessary key elements to test the travel time tomographic inversion approach for the high-resolution characterization of the shallow surface. In this methodological validation test, travel-time tomography demonstrated to be a powerful tool with a relatively high capacity for imaging in detail the lithological contrasts of evaporitic sequences located at very shallow depths, when integrated with additional geological and geophysical data., Convenio Colaboración CSIC-ENRESA. Código CSIC: 20133830, Peer reviewed