BUSCADOR RECOLECTA

This research was funded by the French National Research Agency ANR (ANR-13-BSV6-0007-01, ANK-13-BSV6-0007-02 and ANK-13-BSV6-0007-05). The high resolution mass spectrometer was financed (SMHART project, 35069) by the European Regional Development Fund (ERDF), the Conseil Regional du Centre, the French National Institute for Agricultural Research (INRA) and the French National Institute of Health and Medical Research (Inserm), ARN acknowledges funding through Grants CGL2011-25906 (Ministerio de Economia, Spain)., Chicken eggshell is a biomineral composed of 95% calcite calcium carbonate mineral and of 3.5% organic matrix proteins. The assembly of mineral and its structural organization is controlled by its organic matrix. In a recent study [1], we have used quantitative proteomic, bioinformatic and functional analyses to explore the distribution of 216 eggshell matrix proteins at four key stages of shell mineralization defined as: (1) widespread deposition of amorphous calcium carbonate (ACC), (2) ACC transformation into crystalline calcite aggregates, (3) formation of larger calcite crystal units and (4) rapid growth of calcite as columnar structure with preferential crystal orientation. The current article detailed the quantitative analysis performed at the four stages of shell mineralization to determine the proteins which are the most abundant. Additionally, we reported the enriched GO terms and described the presence of 35 antimicrobial proteins equally distributed at all stages to keep the egg free of bacteria and of 81 proteins, the function of which could not be ascribed., French National Research Agency (ANR) ANR-13-BSV6-0007-01 ANK-13-BSV6-0007-02 ANK-13-BSV6-0007-05, European Union (EU) 35069, Region Centre-Val de Loire, French National Institute for Agricultural Research (INRA), Institut National de la Sante et de la Recherche Medicale (Inserm), Ministerio de Economia, Spain CGL2011-25906

This work was supported by the projects MAT2010-20370 and MAT2013-43922-R (European FEDER support included, MICINN, Spain), PI10/02295 (Instituto de Salud Carlos III, Fondo de Investigacion Sanitaria, FEDER funds) and P07-FQM2496, P10-CTS-6270 and P07-FQM3099 (Junta de Andalucia, Spain)., The aim of this data article is to provide data for a basic knowledge of the properties of lipid nanocapsules, a new colloidal system with very promising applications in drug delivery. Firstly, we pay attention on how it is possible to determine their surface composition by means of electrokinetics measurements. On the other hand, we provide experimental evidences for a better understanding of the factors that determine the interactions of these nanoparticles with cells as a necessary step to guide the design of the most effective formulations. Additionally, we supply information about encapsulation efficiency of docetaxel, a potent chemotherapy drug, inside nanocapsules supporting the experimental cytotoxicity results of these nanosystems., European Union (EU) MAT2010-20370 MAT2013-43922-R, Instituto de Salud Carlos III, Fondo de Investigacion Sanitaria, FEDER funds PI10/02295, Junta de Andalucia P07-FQM2496 P10-CTS-6270 P07-FQM3099, Spanish Government