BUSCADOR RECOLECTA

To investigate the safety and immunogenicity of a modified vaccinia virus Ankara vector expressing HIV-1 antigens from clade B (MVA-B), a phase-I, doubled-blind placebo-controlled trial was performed., Peer reviewed

Attenuated poxvirus vectors expressing human immunodeficiency virus type 1 (HIV-1) antigens are considered promising HIV/AIDS vaccine candidates. Here, we describe the nature of T cell immune responses induced in healthy volunteers participating in a phase I clinical trial in Spain after intramuscular administration of three doses of the recombinant MVA-B-expressing monomeric gp120 and the fused Gag-Pol-Nef (GPN) polyprotein of clade B. The majority (92.3%) of the volunteers immunized had a positive specific T cell response at any time postvaccination as detected by gamma interferon (IFN-γ) intracellular cytokine staining (ICS) assay. The CD4(+) T cell responses were predominantly Env directed, whereas the CD8(+) T cell responses were similarly distributed against Env, Gag, and GPN. The proportion of responders after two doses of MVA-B was similar to that obtained after the third dose of MVA-B vaccination, and the responses were sustained (84.6% at week 48). Vaccine-induced CD8(+) T cells to HIV-1 antigens after 1 year were polyfunctional and distributed mainly within the effector memory (TEM) and terminally differentiated effector memory (TEMRA) T cell populations. Antivector T cell responses were mostly induced by CD8(+) T cells, highly polyfunctional, and of TEMRA phenotype. These findings demonstrate that the poxvirus MVA-B vaccine candidate given alone is highly immunogenic, inducing broad, polyfunctional, and long-lasting CD4 and CD8 T cell responses to HIV-1 antigens, with preference for TEM. Thus, on the basis of the immune profile of MVA-B in humans, this immunogen can be considered a promising HIV/AIDS vaccine candidate., Peer reviewed

Poster XVIII SIEBM, Durante 2010 y 2011 se llevaron a cabo varias campañas multidisciplinares en el Cañón de Avilés y el banco de Galicia para estudiar sus hábitats y especies bajo el proyecto LIFE+ INDEMARES. Concretamente, este trabajo se centró en la macrofauna endobentónica de fondos blandos de esta montaña submarina y del complejo de cañones. Se realizaron muestreos cuantitativos de la macroinfauna bentónica con una draga box corer, tras confirmar la presencia de tipos sedimentarios blandos en las estaciones seleccionadas. Con esta draga de fango se obtuvieron muestras para el estudio faunístico y para el estudio granulométrico. El programa de muestreo en el banco de Galicia comprendió un total de 28 estaciones, entre 683 y 2274 m, mientras que en el Cañón de Avilés se muestrearon un total de 57 estaciones entre 83 y 1881 m. Los resultados de los diferentes análisis granulométricos revelaron que los sedimentos del banco de Galicia están compuestos principalmente por arenas medias con bajo contenido orgánico, en tanto que en el Cañón de Avilés el tamaño de grano decreció con la profundidad, desde arenas muy gruesas hasta fango. A nivel faunístico, en el banco de Galicia se observaron menores valores de abundancia y de diversidad (abundancia media por estación: 554 ind/m2, rango: 67-1478 ind/m2; 182 especies, rango: 6-49 especies; diversidad: 2.5-5.1) que en el Cañón de Avilés (abundancia media por estación: 994 ind/m2, rango: 544-2811 ind/m2; 505 especies, rango: 29-81 especies; diversidad: 4.5-5.8). Los poliquetos fueron el grupo faunístico dominante en ambas zonas, tanto en abundancia como en número de especies. Concretamente en el banco de Galicia los poliquetos fueron seguidos en abundancia por los moluscos, equinodermos, crustáceos y el grupo Otros, mientras que en el cañón de Avilés a los poliquetos le siguieron los crustáceos, moluscos, equinodermos, y el grupo Otros. Once familias registraron más del 50% de los individuos en la montaña submarina: los poliquetos Spionidae, Syllidae, Ampharetidae, Poecilochaetidae, Cirratulidae, Paraonidae, Glyceridae y Sabeliidae, los bivalvos Limopsidae y Thyasiridae, y las ofiuras Ophiacanthidae. En el cañón de Avilés fueron trece las familias que alcanzaron más del 50% de dominancia: los poliquetos Spionidae, Paraonidae, Ampharetidae, Sabellidae, Capitellidae, Syllidae, Maldanidae, Onuphidae y Cirratulidae, los bivalvos Bivalvia spp. y Thyasiridae, los nermetinos, y los equinoideos. A nivel específico, las especies más abundantes del banco de Galicia fueron los poliquetos Aurospio dibranchiata, Poecilochaetus sp., Glycera lapidum y Palposyllis prosostoma, junto con los bivalvos Limopsis cristata y Thyasira succisa, mientras que en el cañón de Avilés las especies dominantes fueron los poliquetos Pterolysippe vanelli y Levinsenia flava, los nemertinos, los bivalvos (Bivalvia indet.), los equinoideos (Echinoidea indet.) y el sipuncúlido Onchnesoma steenstrupii steenstrupii. A nivel de comunidades, en el Banco de Galicia los análisis multivariantes distinguieron claramente las estaciones más someras de arenas medias, de las estaciones más profundas de arenas finas, siendo la profundidad, el contenido en fango y el tamaño medio de grano los principales factores que estructuraron las comunidades bentónicas asentadas. En el Cañón de Avilés se determinaron también varios grupos de estaciones en las que se distinguían las estaciones someras con altos contenidos en arenas gruesas, las estaciones de profundidad intermedia con altos contenidos en arenas finas, y las estaciones profundas con las granulometrías más finas, siendo la profundidad, el contenido en arena fina y el contenido en fango los factores estructurantes más importantes.

Situación del stock de la sardina

Veu.

8 programes especials del programa "Fora d'hores" de Ràdio 4 produït pel "Laboratori de Produccions Sonores de Ficció i Entreteniment" de la Llicenciatura de Comunicació Audiovisual de la UAB, Emesos entre el juny i el setembre de 2011

The dataset consists of three comma-delimited plain text files corresponding to (i) Epigenotypic data of maternal modules, (ii) phenotypic data of maternal modules, and (iii) phenotypic data of the subprogenies obtained in the greenhouse, for different modules from adult, wild-grown, field-sampled plants of the shrub Lavandula latifolia (Lamiaceae). Five modules, each consisting of a terminal branchlet bearing one inflorescence and its subtending leaves, were collected from each of 15 wild-growing L. latifolia plants from a large population growing near Arroyo Aguaderillos in the Sierra de Cazorla (Jaén province, southeastern Spain; geographical coordinates 37.96157 N, 2.88389 W). Each module was characterized epigenotypically by the methylation state of methylation-sensitive amplified fragment length polymorphism markers (MS-AFLP), and phenotypically by fecundity-related traits (inflorescence length, and size, number and mass of seeds produced). Seeds from the different modules were sown in the greenhouse and resulting ‘subprogenies’ characterized phenotypically (germination probability and time to emergence, seedling size, susceptibility to fungal disease). For MS-AFLP data, each column refer to a specific (although anonymous) marker, identified by primer combination and size (base pairs)., This dataset includes three files containing (i) Epigenotypic data of maternal modules, (ii) phenotypic data of maternal modules, and (iii) phenotypic data of greenhouse subprogenies for different modules of 15 adult, wild-grown, field-sampled plants of the shrub Lavandula latifolia., Partial support for this study was provided by grants PID2019-104365GB-I00 (Ministerio de Ciencia e Innovación, Spanish Government) and P18-FR-4413 (Consejería de Transformación Económica, Industria, Conocimiento y Universidades, Andalusian Government)., Five modules, each consisting of a terminal branchlet bearing one inflorescence and its subtending leaves, were collected from each of 15 wild-growing L. latifolia plants from a large population growing near Arroyo Aguaderillos in the Sierra de Cazorla (Jaén province, southeastern Spain; geographical coordinates 37.96157 N, 2.88389 W). Each module was characterized epigenotypically by the methylation state of methylation-sensitive amplified fragment length polymorphism markers (MS-AFLP), and phenotypically by fecundity-related traits (inflorescence length, and size, number and mass of seeds produced). Seeds from the different modules were sown in the greenhouse and resulting ‘subprogenies’ characterized phenotypically (germination probability and time to emergence, seedling size, susceptibility to fungal disease). For MS-AFLP data, each column refer to a specific (although anonymous) marker, identified by primer combination and size (base pairs). Further details can be obtained in Herrera, Carlos M.; Medrano, Mónica; Bazaga, Pilar; Alonso, Conchita. 2022. Ecological significance of intraplant variation: epigenetic mosaicism in Lavandula latifolia plants predicts extant and transgenerational variability of fecundity-related traits. Journal of Ecology (in press)., Peer reviewed

Published as part of Battiston, Roberto, Ortego, Joaquín, Correas, José R. & Cordero, Pedro J., 2014, A revision of Apteromantis (Mantodea: Mantidae, Amelinae): A comprehensive approach to manage old taxonomic and conservation problems, pp. 65-77 in Zootaxa 3797 (1) on page 71, DOI: 10.11646/zootaxa.3797.1.8, http://zenodo.org/record/4915383, FIGURE 4. (A) Apex of the hypophallus for four specimens of A. bolivari from Morocco (Ab1-4), one specimen of A. bolivari from Portugal (AbP), and three specimens of A. aptera from Spain (Aa1-3). All the drawings have been reduced to the same scale to put in evidence the shape differences. (B) Pseudophallus for A. bolivari and A. aptera., Peer reviewed

Published as part of Battiston, Roberto, Ortego, Joaquín, Correas, José R. & Cordero, Pedro J., 2014, A revision of Apteromantis (Mantodea: Mantidae, Amelinae): A comprehensive approach to manage old taxonomic and conservation problems, pp. 65-77 in Zootaxa 3797 (1) on page 69, DOI: 10.11646/zootaxa.3797.1.8, http://zenodo.org/record/4915383, FIGURE 2. Mean (± S.E.) of (A) Female head shape and (B) male genitalia shape for A. aptera and A. bolivari based on the first principal component scores (PC1) extracted from Fourier analyses., Peer reviewed

Published as part of Battiston, Roberto, Ortego, Joaquín, Correas, José R. & Cordero, Pedro J., 2014, A revision of Apteromantis (Mantodea: Mantidae, Amelinae): A comprehensive approach to manage old taxonomic and conservation problems, pp. 65-77 in Zootaxa 3797 (1) on page 73, DOI: 10.11646/zootaxa.3797.1.8, http://zenodo.org/record/4915383, FIGURE 6. Phylograms showing the relationships between Apteromantis aptera and A. bolivari haplotypes for the COI mitochondrial gene using minimum evolution (ME, above branches) and neighbour-joining (NJ, below branches) methods. Only bootstrap support values over 60% are shown. The tree was rooted with a sequence of Ameles sp., Peer reviewed