BUSCADOR RECOLECTA

This dataset in an Excel file compares the wave of globalization before the outbreak of the Great Recession in 2007 with its alleged historical antecedent before the outbreak of World War One. We describe trends in trade and openness, estimate the gains from trade and investigate the proximate causes of the growth of openness. We argue that the conventional wisdom has to be revised. The first wave of globalization started around 1820 and culminated around 1870. In the next century, trade continued to grow, with the exception of the Great Depression, but openness and gains fluctuated widely. Growth resumed in the early 1970s. By 2007, the world was more open than a century earlier and its inhabitants gained from trade substantially more than their ancestors did. The current wave of globalization, in spite of some similarities with previous trends, has no historical antecedents. This dataset is related to the working paper "A tale of two globalizations : gains for trade and openness 1800-2010" by by Giovanni Federico and Antonio Tena Junguito, available on: http://hdl.handle.net/10016/22354

This dataset is supporting information to the paper pubished in the Working papers in Economic History series, n. 16-01., This dataset in an Excel file presents our data-base on world trade from 1800 to 1938. We have collected or estimated series of imports and exports, at current and constant (1913) prices and at current and at constant (1913) borders, for 149 polities. After a short review of the available series, we describe the methods for the construction of the data-base. We then deal with the criteria for the inclusion of polities, the representativeness of our series, the main types of sources, the procedures of deflation and, when necessary, of adjustments to 1913 borders. We discuss the details of the estimation of our polity series in Appendix B. Following Feinstein and Thomas (2001), we assess the reliability of our polity estimates. In the last two sections we present our trade series at current and 1913 borders and compare them with other available series. This dataset is related to the working paper "World trade, 1800-1938 : a new data-set" by Giovanni Federico and Antonio Tena Junguito, available on: http://hdl.handle.net/10016/22222.

Pru p 3-specific IgE values obtained by ImmunoCAP in LTP-allergic patients and tolerant controls., Peer reviewed

The difference in the localization / internalization of the toll-like receptors was determined by confocal microscopy and flow cytometre. These differences between both was due to the differential location of them, since the expression of TLR4 is at the cell surface, while TLR7 is at intracellular compartments, Peer reviewed

Peer reviewed

Data showed are changes in the maturation index of CD83, CD86 and PD-L1 in allergic patient and tolerant control., Peer reviewed

Production of cytokine into the culture supernatant. In the case of TLR4, only significant increases of IL-5 were observed in allergic patients compared to tolerant controls when stimulating with TLR4lig-Pp3 and TLR4lig plus Pp3 peptide in separately way. No differences in the induction of IL-10 production were observed in allergic patients compared to tolerant controls, Peer reviewed

Production of cytokine into the culture supernatant from DCs. Our analysis in allergic patients compared to tolerant controls detected significant increases of IL-5 and IFN with all the conditions containing TLR7lig (TLR7lig, TLR7lig-Pp3 and TLR7lig plus Pp3 in separately way). we observed that TLR7lig-Pp3 induced significant lower IL-4 and IL-5 levels whilst higher IFNγ levels compared to the Pp3 only in allergic patients, indicating the specific immunomodulatory capacity of this compound., Peer reviewed

Data indicated that only TLR7lig-Pp3 led to significantly increased in the proliferation index of CD3+T-cells in allergic patients compared to tolerant controls, while TLR4lig-Pp3 seemed stimulate the T-cells proliferation without inducing a difference between groups. Moreover, in allergic patients there was a significant increase in CD3+ and CD4+ T-cells proliferation after stimulation with TLR4lig-Pp3 vs TLRlig and vs TLR4lig plus Pp3 peptide; additionally, TLR7lig-Pp3 induced a specific proliferative response of CD3+T-cells compared to TLR7lig and TLR7lig plus Pp3 peptide., Peer reviewed

Regarding the cytokine profile produced during the proliferative response, the most interesting results indicated that both TLRnlig-Pp3 induced a decrease of IL-4 and IL-5 levels compared to Pp3 peptide (alone), being significant for IL-5 with TLR4lig-Pp3, and an increase of IFN being significant only for TLR7lig-Pp3 in allergic patients., Peer reviewed