Resultados de investigación

4 files, Additional data derived from "Bivalves present the largest and most diversified repertoire of Toll-like receptors in the animal kingdom, suggesting broad-spectrum pathogen recognition in marine waters". -TLR sequences indetified in the annotation of 85 metazoan genomes -TLR sequences de novo indentified in the genomes of three mussel species -Snakemake pipeline and script to calculate saturation curves from the salmon output of the mapping of different mussel SRA transcriptomic samples to the mussel genome -Pipeline used to calculate the modulated transcripts for different mussel transcriptomes, Peer reviewed

Gridded monthly climate projection dataset underpinning the IPCC AR6 Interactive Atlas for the impact-relevant variables and indices., The IPCC WG1 Interactive Atlas is an online tool that provides interactive visualizations and geospatial data related to the physical scientific basis of climate change. This platform allows users to explore and visualize geographical information interactively and dynamically. It presents data using maps, charts, and other visualizations, enabling users to understand complex information spatially and temporally. The interactive Atlas includes climate data for relevant variables, key climate indicators, and trends, all derived from climate model simulations., The IPCC-WGI AR6 Interactive Atlas dataset comprises monthly gridded data from global (CMIP5, CMIP6) and regional (CORDEX) model projections for the impact-relevant variables and indices featured in the IPCC Interactive Atlas (https://interactive-atlas.ipcc.ch)., Peer reviewed, 2

Pangenes are clusters of gene models/alleles/haplotypes found in barley assemblies in a similar genomic location., [PRIMA GENDIBAR, PCI2019-103526] supported by Horizon 2020 [A08_23R] funded by Aragón goverment [FAS2022_052, INFRA24018, conexión BCB] funded by CSIC [PID2022-142116OB-I00] by MICIU/AEI/10.13039/501100011033, Peer reviewed

To investigate differences in gene expression during flatfish metamorphosis we selected three key stages in turbot development: pre-metamorphic stage (15 dpf); climax of metamorphosis (30dpf); and post-metamorphic stage (57dpf). These fish were reared under standard production conditions at 18ºC. The migrant and non-migrant eyes and their respective surrounding tissue were directed for each stage and RNA were extracted. Libraries were sequenced on a BGISEQ-500 platform and single-end reads of 50 base pairs length were generated per sample, Flatfish have evolved their visual system to meet the demands of their environment through a fascinating process of metamorphosis. This morphological transformation involves a significant change in lifestyle from pelagic to benthic, accompanied by changes in body structure to achieve an asymmetrical flat shape. However, the fundamental change lies in the migration of one eye from its original position to the opposite location on the body. Although the role of thyroid hormone in triggering flatfish metamorphosis is well established, the specific gene regulatory network responsible for this extraordinary eye migration is still unknown. Here we show a global view through the creation of a general map of gene expression during the metamorphic process, encompassing both migrant and non-migrant eyes. Our research uncovers significant differences between migrant and non-migrant eyes of turbot in the pre-metamorphic and climax phases, emphasizing genetic disparities crucial for benthic adaptation, MCIN/AEI/10.13039/501100011033 (AGL2017-89648P and PID2021-126511OB-100 to J.R.) and “ERDF A way of making Europe”, by the “European Union”, No

Raw sequence reads data, Illumina sequencing of mussel hemocytes transcriptome after viral VHSV stimulation: three control and three infected individuals 24 hours after the stimulation, Peer reviewed

Peer reviewed

Protein sequences from transcription factors curated at https://footprintdb.eead.csic.es, footprintDB is developed by Alvaro Sebastian Yague and Bruno Contreras Moreira and it is maintained at the Computational & Structural Biology group (Zaragoza, Spain), with funding from ARAID, CSIC and the 2008 Euro Research Program [EUI2008-03612]., Peer reviewed

Este anexo incluye información relevante no incluida en el libro impreso., This compilation encompasses all records of inland water animals and plants in Madrid County over the years. It is an appendix to the book "Ecología acuática de Madrid", published by Editorial CSIC in 2020., Peer reviewed

Contents: Repo Contents. -- System Requirements. -- Installation Guide. -- Demo. -- License. -- Issues. -- Citation, Peer reviewed

Expression profiling by high throughput sequencing. -- To delve deeper into the biological mechanisms implicated in the MIA effects on neurodevelopment processes, we have generated neural stem cell lines from fetuses carried by pregnant mice treated with Poly I:C with the aim of investigating the alterations that persist in cultured neurons derived from the differentiation of these neural progenitors., To undertake a comprehensive examination of the molecular mechanisms governing the alterations induced by maternal immune activation (MIA) during gestation that impacts the subsequent neurodevelopment of progeny, we have devised an in vitro model based on neural stem cells (NSCs) sourced from fetuses carried by animals subjected to Poly I:C treatment. These neural progenitors demonstrate proliferative properties and can be effectively differentiated into both neurons and glial cells. Through transcriptomic, proteomic, and phosphoproteomic analyses conducted on these cellular models, in conjunction with counterparts from control treatments, discernible shifts in the expression levels of a specific subset of proteins implicated in neuronal function were elucidated. Noteworthy is the absence of congruence between these alterations and the transcriptomic findings, suggesting a potential dysregulation at the level of protein translation. Furthermore, a discernible discrepancy in the basal phosphorylation of proteins was observed between differentiated cells from both experimental groups, particularly within proteins associated with cytoskeletal architecture and synaptic functionality, notably those belonging to the MAP family. These observed alterations were found to correlate with changes in neuronal function, particularly with respect to synaptic plasticity and the establishment of neuronal synapses, thereby reaffirming previous assertions regarding the potential impact of MAP2 function modulation via its phosphorylation state on neuronal structure and function., Peer reviewed