BUSCADOR RECOLECTA

Propósito. La inteligencia artificial generativa (IAG), capaz de crear contenidos automatizados en toda clase de formatos, supone un gran desafío para medios de comunicación y periodistas. Esta investigación se propone analizar cómo usan los periodistas la IAG y cómo la perciben. Metodología. Con la colaboración de 81 colectivos (asociaciones, colegios profesionales y sindicatos), se ha completado una amplia encuesta (N = 358). Además, para reforzar los aspectos cualitativos de la investigación, se ha realizado una sesión formativa ─con observación participante─ en la que intervinieron ocho periodistas de distintos tipos de medios. Resultados. La IAG forma ya parte de las herramientas periodísticas habituales, aunque tiene todavía un notable margen de crecimiento. Los algoritmos se valoran por su rapidez y eficiencia, pero son temidos porque no siempre respetan principios básicos de la profesión como la veracidad o el rigor. Los periodistas creen que la IAG puede conducirnos a una sustitución de personas por máquinas y ello supondría ─al perderse el control humano─ un periodismo con menos calidad, creatividad y empatía. Seis de cada diez profesionales afirman que en sus empresas no ha habido debate sobre el uso de la IAG. Casi el 75% de las empresas no ha ofrecido a sus trabajadores formación sobre la IAG. Conclusión y aportación original. Para el óptimo desarrollo de la IAG periodística, resulta esencial establecer proyectos integrales sobre cómo, cuándo, para qué y con límites usar la IAG en los medios de comunicación. La formación y el diálogo son elementos claves.

The neuroimmune actions of ethanol have recently gained significant attention.Concurrently, the kynurenine pathway, the main catabolic route of tryptophan (TRP), has emerged as a novel target for modulating drug abuse and as a critical immune regulator. This pathway is implicated in behavioral and cognitive alterations, including anxiety, depression, and memory impairmentconditions closely associated with ethanol (EtOH) dependence. The kynurenine pathway is activated under inflammatory and immune conditions.Objective. We previously demonstrated that chronic EtOH consumption increases kynurenine (KYN) levels in mice. Here, we investigate the effect of EtOH dependence and withdrawal on behavioral and cognitive parameters, the nucleus accumbens (NAc) transcriptome, and KYN, TRP and serotonin (5-HT) levels and KYN/TRP and 5-HT/TRP ratios in mice.Methods. Adult male mice were subjected the Chronic Intermittent Ethanol (CIE) paradigm, a model for dependence and withdrawal. Twenty-four hours post-EtOH exposure, we analyzed behavioral and cognitive parameters, sequenced the NAc transcriptome, and measured KYN, TRP and 5-HT levels as well as KYN/TRP and 5-HT/TRP ratios in plasma, limbic forebrain, cortex and cerebellum using HPLC.Results. The CIE model induced anxiety-like behavior and memory impairment. Transcriptomic analysis of the NAc revealed immune system activation, including upregulation of immune and inflammation-related genes. Furthermore, chronic EtOH exposure increased KYN levels and the KYN/TRP ratio across plasma and brain regions.This study suggests that chronic EtOH exposure induces neuroimmune activation, which may trigger KYN pathway activation and contribute to anxiety and memory deficits observed in the CIE model.

Vídeo donde se muestra la impresión 3D de una malla impresa a partir de la tinta T-IONO-4B. Asociado a la Tesis Doctoral titulada "Formulación de ionogeles e hidrogeles de celulosa procedente del fraccionamiento de la madera y su aplicación en la impresión 3D".

Dataset concerning TiO2 polymorphic transformations in hydrothermal context. It includes some Zr-in-rutile thermometric calculations

IACI (v.0.2) is the first version (0) of the Iberian Actuarial Climate Index, now completed in this new version (0.2) to all the Spanish provinces and autonomous regions from 1961 to 2023. It has been developed at Universidad Complutense de Madrid, in the Department of Actuarial and Financial Economics & Statistics. IACI (v.0.2) has been built following the guidelines that can be found in Zhou, N., Vilar-Zanón, J. L., Garrido, J., & Martínez, A. J. H. (2023, December). On the definition of an actuarial climate index for the Iberian Peninsula. In Anales del Instituto de Actuarios Españoles (No. 29, pp. 37-59). This can be downloaded from: https://doi.org/10.26360/2023_3 This last version of IACI (v.0.2) consists of: TIME EXTENSION: *From 1961 to 2023 PERIODS: *Monthly: January to December. *Seasonal: Seasons are the following -Q1 (DEC, JAN, FEB), -Q2 (MAR, APR, MAY), -Q3 (JUN, JUL, AUG), - Q4 (SEP, OCT, NOV). GEOGRAPHICAL EXTENSION: *Iberian Peninsula (excluding the Canary and Balearic Islands, and the autonomous African cities of Ceuta and Melilla) *The index particularized to the following geographical areas: -Spain (Except the Canary and Balearic Islands and the autonomous African cities of Ceuta and Melilla). -Portugal (continental) . -Andorra. -Spanish provinces: All the Spanish provinces are now included in the IACI (except the Canary and Balearic Islands). -Spanish Autonomous Regions: All except the Canary and Balearic Islands, and the autonomous African cities of Ceuta and Melilla.

Base de datos Phinachi. Estructura y datos de la base creada para el proyecto PHINACHI, Fuentes documentales para el estudio del Patrimonio Histórico Inmueble de Navalcarnero y Chinchón, CAM-Ref. 1659/09.

In the present work, a hybrid hierarchical coating (HHC) system comprising a plasma electrolytic oxidation (PEO) coating and a homogeneously porous structured polycaprolactone (PCL) top-coat layer, loaded with ciprofloxacin (CIP), was developed on Mg3Zn0.4Ca alloy. According to the findings, the HHC system avoided burst release and ensured gradual drug elution (64% over 240 h). The multi-level protection of the magnesium alloy is achieved through sealing of the PEO coating pores by the polymer layer and the inhibiting effect of CIP (up to 74%). The corrosion inhibition effect of HHC and the eluted drug is associated with the formation of insoluble CIP-Me (Mg/Ca) chelates that repair the defects in the HHC and impede the access of corrosive species as corroborated by FTIR spectra, EIS and SEM images after 24 h of immersion. Therefore, CIP participates in an active protection mechanism by interacting with cations coming through the damaged coating.

Assessing chronic pain in dogs has been greatly favoured by the development of Owner-Reported Outcome Measures. Among them, the Liverpool Osteoarthritis in Dogs (LOAD) has been widely used for this purpose. Most of these tools have been written in English and its use by non-English natives requires not only translation but also linguistic validation for use by veterinarians and owners. For its use, the LOAD has not undergone translation into Spanish and the objective was to generate a linguistically validated Spanish translation of the LOAD. Following the World Health Organization and the International Society for Pharmacoeconomics and Outcomes Research published guidelines, the original LOAD English version underwent analysis and translation by two native linguists proficient in the target language. Both translations were then reviewed by a third native linguist to identify potential disparities and establish a cohesive translation (reconciliation). Subsequently, an independent linguist, fluent in both English and the target language, conducted the back-translation. Finally, the research team compared the original and back-translated versions to pinpoint and resolve any significant differences. Following the creation of the translated version, a cognitive debriefing was conducted to assess the questionnaire within the target population. A total of 89 surveys were distributed to dog owners of varying ages, genders, and socio-economic backgrounds. Although there were some suggestions and comments, and some adjustments were made, all respondents found the survey to be clear, achieving a linguistic validation of the Spanish LOAD.