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Efficient Strategy for the Parallelization of the Multilevel Fast Multipole Algorithm Using CUDA

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
García García, Eliseo, Delgado Hita, Carlos, Lozano Plata, Lorena, Cátedra Pérez, Manuel Felipe

The multilevel fast multipole algorithm is a popular technique that enables the efficient solution of the method of moments (MoM) matrix equations. In this work, the authors address the adaptation of this method to the compute unified device architecture (CUDA), a relatively new computing infrastructure provided by NVIDIA, and the authors take into account some of the limitations that appear when the geometry under analysis becomes too large to fit into the memory of graphics processing units, Spanish Ministerio de Economia and Competitividad.



Accuracy and Precision Assessment of AoA-Based Indoor Positioning Systems Using InfrastructureLighting and a Position-Sensitive Detector

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Llana Calvo, Álvaro De La, Salido Monzú, David, Lázaro Galilea, José Luis, Gardel Vicente, Alfredo, Bravo Muñoz, Ignacio, Rubiano Muriel, Borja

Unlike GNSS-based outdoor positioning, there is no technological alternative for Indoor Positioning Systems (IPSs) that generally stands out from the others. In indoor contexts, the measurement technologies and localization strategies to be used depend strongly on the application requirements and are complementary to each other. In this work, we present an optical IPS based on a Position-Sensitive Detector (PSD) and exploiting illumination infrastructure to determine the target position by...



A Machine Learning-based Distributed System for Fault Diagnosis with Scalable Detection Quality in Industrial IoT

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Lanza Gutiérrez, José Manuel, Rodrigo, Marino, Wisultschew, Cristian, Otero, Andrés, Portilla, Jorge, Torre, Eduardo de la

In this paper, a methodology based on machine learning for fault detection in continuous processes is presented. It aims to monitor fully distributed scenarios, such as the Tennessee Eastman Process, selected as the use case of this work, where sensors are distributed throughout an industrial plant. A hybrid feature selection approach based on filters and wrappers, called Hybrid Fisher Wrapper method, is proposed to select the most representative sensors to get the highest detection quality for...



Equiareal Shape-from-Template

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Casillas Pérez, David, Pizarro Pérez, Daniel, Fuentes Jiménez, David, Mazo Quintas, Manuel Ramón, Bartoli, Adrien

This paper studies the 3D reconstruction of a deformable surface from a single image and a reference surface, known as the template. This problem is known as Shape-from-Template and has been recently shown to be well-posed for isometric deformations, for which the surface bends without altering geodesics. This pa- per studies the case of equiareal deformations. They are elastic deformations where the local area is pre- served and thus include isometry as a special case. Elas- tic deformations..., Ministerio de Economía y competitividad, Universidad de Alcalá



From Frequency Content to Signal Dynamics Using DNNs

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Pedro Carracedo, Javier De, Fuentes Jiménez, David, Cabrera Umpiérrez, María Fernanda, González Marcos, Ana Pilar

This study developed a novel method for analyzing and decomposing a signal into its main dynamics for small and large timescales. Our proposal is based on a decoupled hybrid system of convolutional and recurrent neural networks that uses as inputs the power spectrum and spectrogram of a given signal, giving as output the dynamic behavior. We define the dynamic classification predicted of the signal using previously known dynamics characterized through training signals: periodic, quasi-periodic..., Life Supporting Technologies Group (LST- UPM)



Towards an Machine Learning-based Edge Computing Oriented Monitoring System for the Desert Border Surveillance Use Case

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Lanza Gutiérrez, José Manuel, Bellazi, Khalifa, Marino , Rodrigo, Riesgo, Teresa

The design of border surveillance systems is critical for most countries in the world, having each border specific needs. This paper focuses on an Internet of Things oriented surveillance system to be deployed in the Sahara Desert, which is composed of many unattended fixed platforms, where the nodes in the edge have a Forward Looking InfraRed (FLIR) camera for field monitoring. To reduce communications and decentralise the processing, IR images should be fully computed on the edge by an...



A survey on Machine Learning Techniques for Routing Optimization in SDN

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Amin, Rashid, Rojas Sánchez, Elisa, Aqdus, Aqsa, Ramzan, Sadia, Casillas-Perez, David, Arco Rodríguez, José Manuel

In conventional networks, there was a tight bond between the control plane and the data plane. The introduction of Software-Defined Networking (SDN) separated these planes, and provided additional features and tools to solve some of the problems of traditional network (i.e., latency, consistency, efficiency). SDN is a flexible networking paradigm that boosts network control, programmability and automation. It proffers many benefits in many areas, including routing. More specifically, for...



Beyond Multi-access Edge Computing: Essentials to realize a Mobile, Constrained Edge

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Rojas Sánchez, Elisa, Guimaraes , Carlos, De La Oliva , Antonio, Bernardos , Carlos J, Gazda , Robert

ETSI Multi-access Edge computing (MEC) main purpose is to improve latency and bandwidth consumption by keeping local traffic local while providing computing resources near the end-user. Despite its clear benefits, the next-generation of hyper-distributed applications (e.g., edge robotics, augmented environments, or smart agriculture) will exacerbate latency and bandwidth requirements, posing significant challenges to today's MEC deployments. In this work, we leverage on the current...



A nonrecursive GR algorithm to extract road networks in high-resolution images from remote sensing

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Bravo Muñoz, Ignacio, Gardel Vicente, Alfredo, Da Silva , Erivaldo Antonio, Araujo Dias, Mauricio, Cardim Pinha, Guilherme

A number of studies address the development of algorithms based on the Growing Region (GR) technique adaptations for extracting road networks in images. However, these algorithms are high-computationally demanding and time-consuming while processing high-resolution images. The aim of this study is to introduce a modified version of the GR algorithm, named Nonrecursive Growing Region (NRGR), to extract road networks in high-resolution images from remote sensing. This study describes how the NRGR...



Application of traffic weighted multi-maps based on disjoint routing areas for static traffic assignment

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Paricio García, Álvaro, López Carmona, Miguel Ángel

Urban traffic congestion is a pressing issue, demanding effective and cost-efficient solutions. This paper develops the Traffic Weighted Multi-Maps (TWM) method to solve the Traffic Assignment Problem in Intelligent Transportation Systems (ITS). TWM offers drivers diverse views of the network, promoting path diversity and adaptability. Providing an optimal TWM configuration to the traffic demand in terms of structure and allocation policy is a challenging issue as it usually depends on the size..., UAH - Catedra MANEDS



Towards visual programming abstractions in Software Defined Networking

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Rojas Sánchez, Elisa, Ollora Zaballa, Eder, Noci Luna, Victoria

Since Software-Defined Networking (SDN) emerged, the research community and industry have developed numerous projects and fostered novel use cases. However, engineers now need to learn how to program the control and data planes, which might slow down technology acceptance. To accelerate it, visual programming abstractions facilitate the incorporation of SDN technologies and assist in creating new applications. So far, very little effort has been made in this field. This letter presents an early..., Comunidad de Madrid, Agencia Estatal de Investigación, Universidad de Alcalá



An approach to patents of prestressed concrete in 20th Century's arquitecture

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Miguel Sánchez, Manuel de, Llorente Zurdo, María Paz, Anaya Díaz, Jesús

Around 1906, there was a discussion in the various publications on reinforced concrete about the problem of how to avoid the cracks on it, due to tension that occurred inside. First attempts to avert it failed since the tension applied to the steel was lost with the passage of time, as much for the hydraulic retraction of the concrete as for the use of not very high strength steels, and also because of the stress imposed were insufficient for targeted outcomes. In 1928, E. Freyssinet registered...



Long-term dynamics of shrub facilitation shape the mixing of evergreen and deciduous oaks in Mediterranean abandoned fields

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Rey Benayas, José María, Villar Salvador, Pedro, Cruz Alonso, Verónica, Ibáñez , Inés, Ruiz Benito, Paloma

Recovery of Mediterranean forests after field abandonment is a slow process, even without propagule limitations. This is mainly due to stressful conditions for seedling establishment. In this context, shrubs play a critical role in facilitating tree recruitment, but how this process unfolds after field abandonment is not entirely known. We evaluated the long-term dynamics of facilitation by the nurse shrub Retama sphaerocarpa in the recruitment of two ecologically contrasting oaks, the...



Forests, savannas, and grasslands: bridging the knowledge gap between ecology and Dynamic Global Vegetation Models

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Baudena, M., Dekker, Sc, Bodegom, Pm. van, Cuesta Poveda, Bárbara, Higgins, Sl, Lehsten, V, Reick, Ch, Rietkerk, M., Scheiter, S, Yin, Z, Zavala Gironés, Miguel Ángel de, Brovkin, V

The forest, savanna, and grassland biomes, andthe transitions between them, are expected to undergo majorchanges in the future due to global climate change. Dynamicglobal vegetation models (DGVMs) are very useful for understandingvegetation dynamics under the present climate,and for predicting its changes under future conditions. However,several DGVMs display high uncertainty in predictingvegetation in tropical areas. Here we perform a comparativeanalysis of three different DGVMs (JSBACH, LPJ-...



El español hablado por los bubis y los fang de Guinea Ecuatorial. Valoraciones desde la comunidad guineoecuatoriana en Madrid, The Spanish spoken by Bubi and Fang of Equatorial Guinea. Evaluations from the Equatoguinean community in Madrid

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Schlumpf, Sandra

Los guineoecuatorianos constituyen un colectivo de inmigrantes hispanohablantes con una presencia estable y longeva en la Comunidad de Madrid, de actualmente unas 9.000 personas. Una característica principal de esta comunidad –y de la sociedad guineoecuatoriana en general– son las divisiones étnicas internas, especialmente entre bubis y fang. Mientras que los fang representan la etnia mayoritaria de Guinea Ecuatorial y el grupo políticamente dominante desde la independencia del país en 1968,..., The Equatoguineans constitute a group of Spanish-speaking immigrants with a stable and long-lasting presence in the Autonomous Community of Madrid, with currently about 9.000 individuals. An important characteristic of this group –and of the Equatoguinean society as a whole– are the internal ethnic differences, especially between Bubi and Fang. The Fang represent the most numerous ethnic group of Equatorial Guinea and hold the political power since independence in 1968, whereas the Bubi are the...



Salvadores lingüísticos: intérpretes voluntarios en los hospitales de la Costa del Sol, Linguistic rescuers: volunteer interpreters in the hospitals of Costa del Sol

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Ávila Barranquero, Cintia

Hoy en día, en España, vivimos en una sociedad globalizada y multicultural donde coexisten diferentes culturas y nacionalidades y cuyos habitantes hablan diferentes lenguas. Por esta razón, han surgido las necesidades comunicativas entre sus habitantes. La primera barrera a la que se enfrenta el inmigrante o el turista que llega a nuestro país es la lingüística, sobre todo, en los servicios públicos; por ejemplo, cuando tienen que asistir a una consulta médica, a la comisaría, etc. y no..., Today, in Spain, we live in a globalized and multicultural society where different cultures and nationalities coexist and whose inhabitants speak different languages. For this reason, communication needs have emerged among its inhabitants. The first barrier faced by immigrants or tourists arriving in our country is the linguistic barrier, especially in public services, for example, when they have to attend a medical consultation, the police station, etc. and they do not have a professional..., Máster Universitario en Comunicación Intercultural, Interpretación y Traducción en los Servicios Públicos. Especialidad en Inglés-Español (M045)



Early crack detection using modified spectral clustering method assisted with FE analysis for distress anticipation in cement-based composites

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Vedrtnam , Ajitanshu, Kumar, Santosh, Barluenga Badiola, Gonzalo, Chaturvedi, Shashikant

The present work reports an efficient way of capturing real-time crack propagation in concrete structures. The modified spectral analysis based algorithm and finite element modeling (FEM) were used for crack detection and quantitative analysis of crack propagation. Crack propagation was captured in cement-based composite (CBC) containing saw dust and M20 grade concrete under compressive loading using a simple and inexpensive 8-megapixel mobile phone camera. The randomly selected images showing..., This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant Agreement No 754382, GOT ENERGY TALENT.



Connect smart cities and heritage through augmented reality

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Castaño Perea, Enrique María, Labrador Arroyo, Félix, Fuente Prieto, Julián de la

This chapter aims to connect the digital resources of knowledge with the historical and cultural heritage in the context of smart cities. Speciically, combining the joint intervention in the Real Sitio of El Pardo and Aranjuez, as well as the Foundation Square of the University of Alcalá, both in Spain. Through traditional historical research and the innovative use of new technologies like augmented reality (AR), a historical, biological and cultural heritage is conserved, consisting of forests...



Students' Perception of Metaverses for Online Learning in Higher Education: Hype or Hope?

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Rojas Sánchez, Elisa, Hülsmann , Xenia, Estriégana Valdehita, Rosa María, Rückert , Frank, García Esteban, Soraya

Online learning environments have been widely adopted, particularly during the COVID-19 pandemic. Today, their usage is envisioned for multiple teaching scenarios, including international courses involving students from different locations. However, as e-learning frameworks lack many advantages of physical interaction, diverse technologies to enhance the learning experience in this regard, including the use of metaverses, are currently in demand. In this study, we implemented an educational...



An Artificial Neural Network for Analyzing Overall Uniformity in Outdoor Lighting Systems

Repositorio: e_Buah Biblioteca Digital Universidad de Alcalá
Castillo Sequera, José Luis, Del Corte Valiente, Antonio, Castillo Martínez, Ana, Gómez Pulido, José Manuel, Gutiérrez Martínez, José María

Street lighting installations are an essential service for modern life due to their capability of creating a welcoming feeling at nighttime. Nevertheless, several studies have highlighted that it is possible to improve the quality of the light significantly improving the uniformity of the illuminance. The main difficulty arises when trying to improve some of the installation's characteristics based only on statistical analysis of the light distribution. This paper presents a new...



Estimating textural fractions of the USDA using those of the International System: A quantile approach

Repositorio: Arias Montano. Repositorio Institucional de la Universidad de Huelva
Corral Pazos de Provens, Eva, Rapp Arrarás, Ígor|||0000-0002-6158-4738, Domingo Santos, Juan Manuel|||0000-0001-7032-0366

Este artículo forma parte de una trilogía centrada en la revisión de los principales problemas que tiene uno de los factores más importantes de la Ecuación Universal de Pérdidas de Suelo (USLE), en concreto el Factor K de erosionabilidad del suelo. Se plantea un enfoque para solucionar la falta de correspondencias directas entre clasificaciones texturales de suelos., In soil science, the two most frequently used classification systems for the soil particle size distribution are the schemes by the United States Department of Agriculture (USDA) and the so-called International System (IS), whose difference is the upper particle size limit of the silt fraction, namely, 0.02 mm for the IS and 0.05 mm for the USDA system. The existence of these and other systems creates a disparity that hinders and prevents the use and exchange of soil information worldwide. To..., Funding for open access charge: Universidad de Huelva / CBUA



Academic-professional mobility and internationalization of nursing: contributions of the Bologna process, Mobilidade acadêmico-profissional e internacionalização da enfermagem: contributos do processo de Bolonha, Movilidad académico-profesional e internacionalización de la enfermería: aportes del proceso de Bolonia

Repositorio: Arias Montano. Repositorio Institucional de la Universidad de Huelva
Lino, Murielk Motta, Martini, Jussara Gue, Barbieri Figueiredo, Maria do Céu

Objective: to understand the contributions of the Bologna Process to academic-professional mobility of Nursing. Method: a descriptive exploratory qualitative research. Open interviews were conducted with six PhD nurses, nursing professors, with more than 20 years of experience and who experienced the changes that occurred in higher education in post-Bologna nursing. The interviews took place in the Health or Nursing Schools of the north, center and south regions of Portugal, between January and...



Environmental management and potential valorization of wastes generated in passive treatments of fertilizer industry effluents

Repositorio: Arias Montano. Repositorio Institucional de la Universidad de Huelva
Millán Becerro, Ricardo, Macías Suárez, Francisco, Ruiz Cánovas, Carlos, Pérez López, Rafael|||0000-0002-5916-462X, Fuentes López, José María

A phosphogypsum stack located in SW Spain releases highly acidic and contaminated leachates to the surrounding estuarine environment. Column experiments, based on a mixture of an alkaline reagent (i.e., MgO or Ca(OH)2) dispersed in an inert matrix (dispersed alkaline substrate (DAS) technology), have shown high effectiveness for the treatment of phosphogypsum leachates. MgO-DAS and Ca(OH)2-DAS treatment systems achieved near total removal of PO4, F, Fe, Zn, Al, Cr, Cd, U, and As, with initial..., This work was supported by the Spanish Ministry of Economy and Competitiveness, the European Regional Development Fund and the University of Huelva under the research projects CAPOTE (MINECO; CGL 2017-86050-R), VALOREY (MINECO; RTI 2018-101276-J-I00) and EMFHA-SIST (FEDER; UHU-1253533). F. Macías was funded by the R&D FEDER Andalucía 2014–2020 call through the project RENOVAME (FEDER; UHU-1255729). Funding for open access charge: Universidad de Huelva/CBUA.



The use of plant-derived bioactive compounds to target cancer stem cells and modulate tumor microenvironment

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

In the last decades cancer has been considered as an epigenetic dysfunction, given the profound role of diet and lifestyle in cancer prevention and the determination of cancer risk. A plethora of recent publications have addressed the specific role of several environmental factors, such as nutritional habits, behavior, stress and toxins in the regulation of the physiological and cancer epigenome. In particular, plant-derived bioactive nutrients have been seen to positively affect normal cell...

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Exploring factors influencing the severity of pregnancy anemia in India: a study using proportional odds model

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Pregnancy-associated anemia is a significant health issue that poses negative consequences for both the mother and the developing fetus. This study explores the triggering factors of anemia among pregnant females in India, utilizing data from the Demographic and Health Survey 2019–21. Chi-squared and gamma tests were conducted to find out the relationship between anemia and various socioeconomic and sociodemographic elements. Furthermore, ordinal logistic regression and multinomial logistic...

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Potential Role of the Mitochondria for the Dermatological Treatment of Papillon-Lefèvre

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disorder caused by mutations in the Cathepsin C (CTSC) gene, characterized by periodontitis and palmoplantar hyperkeratosis. The main inflammatory deficiencies include oxidative stress and autophagic dysfunction. Mitochondria are the main source of reactive oxygen species; their impaired function is related to skin diseases and periodontitis. The mitochondrial function has been evaluated in PLS and mitochondria have been targeted...



The Molecular Basis of Different Approaches for the Study of Cancer Stem Cells and the Advantages and Disadvantages of a Three-Dimensional Culture

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Cancer stem cells (CSCs) are a rare tumor subpopulation with high differentiation, proliferative and tumorigenic potential compared to the remaining tumor population. CSCs were first discovered by Bonnet and Dick in 1997 in acute myeloid leukemia. The identification and isolation of these cells in this pioneering study were carried out through the flow cytometry, exploiting the presence of specific cell surface molecular markers (CD34+/CD38−). In the following years, different strategies and...



RNA Interference Strategies for Future Management of Plant Pathogenic Fungi: Prospects and Challenges

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Plant pathogenic fungi are the largest group of disease-causing agents on crop plants and represent a persistent and significant threat to agriculture worldwide. Conventional approaches based on the use of pesticides raise social concern for the impact on the environment and human health and alternative control methods are urgently needed. The rapid improvement and extensive implementation of RNA interference (RNAi) technology for various model and non-model organisms has provided the initial...



Inhibition of the NLRP3 inflammasome prevents ovarian aging

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Inflammation is a hallmark of aging and is negatively affecting female fertility. In this study, we evaluate the role of the NLRP3 inflammasome in ovarian aging and female fertility. Age-dependent increased expression of NLRP3 in the ovary was observed in WT mice during reproductive aging. High expression of NLRP3, caspase-1, and IL-1β was also observed in granulosa cells from patients with ovarian insufficiency. Ablation of NLRP3 improved the survival and pregnancy rates and increased anti-...



Rosa x hybrida extracts with dual actions: Antiproliferative effects against tumour cells and inhibitor of Alzheimer disease

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Edible flowers are being used as a new ingredient in modern gastronomy. Recently, these products have also gained interest as an important source of phenolic compounds with potential for biomedical applications. The present work studied a methanolic extract of Rosa x hybrida in which 35 individual phenolic compounds were identified. The extract has been evaluated for its antiproliferative properties in ovarian carcinoma cells. Results showed that the antiproliferative effect was associated with...

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Ultra-Small Iron Nanoparticles Target Mitochondria Inducing Autophagy, Acting on Mitochondrial DNA and Reducing Respiration

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The application of metallic nanoparticles (materials with size at least in one dimension ranging from 1 to 100 nm) as a new therapeutic tool will improve the diagnosis and treatment of diseases. The mitochondria could be a therapeutic target to treat pathologies whose origin lies in mitochondrial dysfunctions or whose progression is dependent on mitochondrial function. We aimed to study the subcellular distribution of 2-4 nm iron nanoparticles and its effect on mitochondrial DNA (mtDNA),...



The central role of mitochondria in the relationship between dietary lipids and cancer progression

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Evidence demonstrates the importance of lipid metabolism and signaling in cancer cell biology. De novo lipogenesis is an important source of lipids for cancer cells, but exogenous lipid uptake remains essential for many cancer cells. Dietary lipids can modify lipids present in tumor microenvironment affecting cancer cell metabolism. Clinical trials have shown that diets rich in polyunsaturated fatty acids (PUFA) can negatively affect tumor growth. However, certain n-6 PUFAs can also contribute...

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NLRP3 inflammasome inhibition rescues Hutchinson-Gilford Progeria cellular phenotype and extend longevity of an animal model

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Inflammation is a hallmark of aging and accelerated aging syndromes. In this context, inflammation has been associated to the pathophysiology of Hutchinson–Gilford progeria syndrome (HGPS). In this study, we report that progeroid skin fibroblasts and animal models present an hyperactivation of the NLRP3-inflammasome complex. High expression of NLRP3 and caspase 1 was also observed in skin fibroblasts from HGPS associated to the nuclei morphology. Lymphoblast from HGPS also showed increased...

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Mislocalization of SMN from the I-band and M-band in human skeletal myofibers in spinal muscular atrophy associates with primary structural alterations of the sarcomere

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

pinal muscular atrophy (SMA) is caused by a deletion or mutation of the survival motor neuron 1 (SMN1) gene. Reduced SMN levels lead to motor neuron degeneration and muscular atrophy. SMN protein localizes to the cytoplasm and Cajal bodies. Moreover, in myofibrils from Drosophila and mice, SMN is a sarcomeric protein localized to the Z-disc. Although SMN participates in multiple functions, including the biogenesis of spliceosomal small nuclear ribonucleoproteins, its role in the sarcomere is...

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Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Aging is the major risk factor for many metabolic chronic diseases. Several metabolic pathways suffer a progressive impairment during aging including body composition and insulin resistance which are associated to autophagy dysfunction and increased inflammation. Many of these alterations are aggravated by non-healthy lifestyle such as obesity and hypercaloric diet which have been shown to accelerate aging. Here, we show that the deleterious effect of hypercaloric diets is reverted by the NLRP3...

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A Diet Rich in Saturated Fat and Cholesterol Aggravates the Effect of Bacterial Lipopolysaccharide on Alveolar Bone Loss in a Rabbit Model of Periodontal Disease

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

ncreasing evidence connects periodontitis with a variety of systemic diseases, including metabolic syndrome, atherosclerosis, and non-alcoholic fatty liver disease (NAFLD). The proposal of this study was to evaluate the role of diets rich in saturated fat and cholesterol in some aspects of periodontal diseases in a lipopolysaccharide (LPS)-induced model of periodontal disease in rabbits and to assess the influence of a periodontal intervention on hyperlipidemia, atherosclerosis, and NAFLD...



The Absence of NLRP3-inflammasome Modulates Hepatic Fibrosis Progression, Lipid Metabolism, and Inflammation in KO NLRP3 Mice during Aging

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Aging is associated with metabolic changes and low-grade inflammation in several organs, which may be due to NLRP3 inflammasome activation. Methods: Here, we asked whether age-related liver changes such as lipid metabolism and fibrosis are reduced in aged mice lacking the NLRP3 inflammasome. We report reduced protein levels of lipid markers (MTP, FASN, DGAT1), SOD activity, oxidative stress marker PTPRG, and the fibrotic markers TPM2β, COL1-α1 associated with increased GATA4, in NLRP3 deficient...

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Sequential Changes of NLRP3 Inflammasome Activation in Sepsis and its Relationship With Death

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Introduction: Inflammasomes are recognized as key components of the innate immune response in sepsis. We aimed to describe the transcriptional expression of nucleotide-binding domain, leucine-rich repeat–containing receptor, pyrin domain–containing-3 (NLRP3), and serum interleukin-1β (IL-1 β) in critically ill patients, their changes over the first week and their prognostic value in septic patients. Methods: Prospective study including patients with sepsis based on Sepsis-3 definitions and a...

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A novel dominant mutation inCRYABgene leading to a severe phenotype with childhood onset

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Background αB-crystallin is a promiscuous protein involved in numerous cell functions. Mutations in CRYAB have been found in patients with different pathological phenotypes that are not properly understood. Patients can present different diseases like cataracts, muscle weakness, myopathy, cardiomyopathy, respiratory insufficiency or dysphagia, but also a variable combination of these pathologies has been found. These mutations can show either autosomal dominant or recessive mode of inheritance...



VRK1 (Y213H) homozygous mutant impairs Cajal bodies in a hereditary case of distal motor neuropathy

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Background Distal motor neuropathies with a genetic origin have a heterogeneous clinical presentation with overlapping features affecting distal nerves and including spinal muscular atrophies and amyotrophic lateral sclerosis. This indicates that their genetic background is heterogeneous. Patient and methods In this work, we have identified and characterized the genetic and molecular base of a patient with a distal sensorimotor neuropathy of unknown origin. For this study, we performed whole-...

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NLRP3 Inflammasome Inhibition by MCC950 in Aged Mice Improves Health via Enhanced Autophagy and PPARα Activity

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The NLRP3 inflammasome has emerged as an important regulator of metabolic disorders and age-related diseases in NLRP3-deficient mice. In this article, we determine whether, in old mice C57BL6J, the NLRP3 inflammasome inhibitor MCC950 is able to attenuate age-related metabolic syndrome to providing health benefits. We report that MCC950 attenuates metabolic and hepatic dysfunction in aged mice. In addition, MCC950 inhibited the Pi3K/AKT/mTOR pathway, enhanced autophagy, and activated peroxisome...

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Is AMP-Activated Protein Kinase Associated to the Metabolic Changes in Primary Ovarian Insufficiency?

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Primary ovarian insufficiency (POI) is a critical fertility defect characterized by anticipated impairment of the follicular reserve, which pathophysiological mechanisms have not yet been identified. We have investigated the possible relationship between AMP-activated protein kinase (AMPK) and the pathophysiology of POI. We studied 35 POI patients with altered levels of follicle-stimulating hormone (FSH) and estradiol and increased percentage of overweight compared with 20 healthy women. Blood...

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A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Cardiomyocytes are subjected to the intense mechanical stress and metabolic demands of the beating heart. It is unclear whether these cells, which are long-lived and rarely renew, manage to preserve homeostasis on their own. While analyzing macrophages lodged within the healthy myocardium, we discovered that they actively took up material, including mitochondria, derived from cardiomyocytes. Cardiomyocytes ejected dysfunctional mitochondria and other cargo in dedicated membranous particles...

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Pharmacological, non-pharmacological and stem cell therapies for the management of autism spectrum disorders: A focus on human studies

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

In the last decade, the prevalence of autism spectrum disorders (ASD) has dramatically escalated worldwide. Currently available drugs mainly target some co-occurring symptoms of ASD, but are not effective on the core symptoms, namely impairments in communication and social interaction, and the presence of restricted and repetitive behaviors. On the other hand, transplantation of hematopoietic and mesenchymal stem cells in ASD children has been shown promising to stimulate the recruitment,...

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Effects of caloric restriction on immunosurveillance, microbiota and cancer cell phenotype: Possible implications for cancer treatment

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Fasting, caloric restriction and foods or compounds mimicking the biological effects of caloric restriction, known as caloric restriction mimetics, have been associated with a lower risk of age-related diseases, including cardiovascular diseases, cancer and cognitive decline, and a longer lifespan. Reduced calorie intake has been shown to stimulate cancer immunosurveillance, reducing the migration of immunosuppressive regulatory T cells towards the tumor bulk. Autophagy stimulation via...

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Edible flowers as a health promoter: An evidence-based review

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The consumption of edible flowers has increased in recent years because of their wide use in gastronomy as a decorative element or as an ingredient in dishes. In addition to influencing texture, taste or appearance, flowers are rich in bioactive compounds. Scope and approach This review focuses on the composition and nutritional features of edible flowers and their extracts, and their health benefits related to cardiovascular diseases, cancer, neurological diseases, diabetes, obesity, in...

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Mitochondrial Adaptations in the Growing Heart

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The heart pumps blood throughout the whole life of an organism, without rest periods during which to replenish energy or detoxify. Hence, cardiomyocytes, the working units of the heart, have mechanisms to ensure constitutive production of energy and detoxification to preserve fitness and function for decades. Even more challenging, the heart must adapt to the varying conditions of the organism from fetal life to adulthood, old age, and pathological stress. Mitochondria are at the nexus of these...

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Strawberry extracts efficiently counteract inflammatory stress induced by the endotoxin lipopolysaccharide in Human Dermal Fibroblast

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

A protracted pro-inflammatory state is the common denominator in the development, progression and complication of the common chronic diseases. Dietary antioxidants represent an efficient tool to counteract this inflammatory state. The aim of the present work was to evaluate the effects of strawberry extracts on inflammation evoked by E. Coli lipopolysaccharide in Human Dermal Fibroblast, by measuring reactive oxygen species production, apoptosis rate, antioxidant enzymes activity, mitochondria...

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Phytochemical Composition and Cytotoxic Effects on Liver Hepatocellular Carcinoma Cells of Different Berries Following a Simulated In Vitro Gastrointestinal Digestion

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Berry fruits are rich in nutrients and polyphenols, providing potential health benefits. Understanding the factors that affect their bioavailability is becoming of utmost importance for evaluating their biological significance and efficacy as functional food. In this study, the phytochemical composition and the total antioxidant capacity of different varieties of five berries (blackberry, blackcurrant, blueberry, raspberry, and strawberry) were evaluated after an in vitro gastrointestinal...



Are by-products from beeswax recycling process a new promising source of bioactive compounds with biomedical properties?

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

During the process of beeswax recycling, many industrial derivatives are obtained. These matrices may have an interesting healthy and commercial potential but to date they have not been properly studied. The aim of the present work was to evaluate the proximal and phytochemical composition, the antioxidant capacity and cytotoxic effects of two by-products from beeswax recycling process named MUD 1 and MUD 2 on liver hepatocellular carcinoma. Our results showed that MUD 1 presented the highest (...

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Strawberry-Tree Honey Induces Growth Inhibition of Human Colon Cancer Cells and Increases ROS Generation: A Comparison with Manuka Honey

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Honey is a natural product known to modulate several biological activities including cancer. The aim of the present study was to examine the phytochemical content and the antioxidant activity of Strawberry tree (Arbutus unedo) honey (STH) and its cytotoxic properties against human colon adenocarcinoma (HCT-116) and metastatic (LoVo) cell lines in comparison with Manuka (Leptospermum scoparium) honey (MH). Several unifloral STH and MH were analyzed for their phenolic, flavonoid, amino acid and...



The protective effect of acerola (Malpighia emarginata) against oxidative damage in human dermal fibroblasts through the improvement of antioxidant enzyme activity and mitochondrial functionality

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Acerola fruits (Malpighia emarginata DC.) from the central region of Cuba were analyzed to determine their chemical composition and protective capacity against oxidative damage using an in vitro human dermal fibroblast (HDFa) model. The chemical composition analyses showed a high content of vitamin C, total polyphenols, β-carotene and folates in the acerola fruit. From the HPLC-DAD/ESI-MSn analyses, two anthocyanins (cyanidin 3-O-rhamnoside and pelargonidin 3-O-rhamnoside), three...

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Strawberry (cv. Romina) Methanolic Extract and Anthocyanin-Enriched Fraction Improve Lipid Profile and Antioxidant Status in HepG2 Cells

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Dyslipidemia and oxidation of low density lipoproteins (LDL) are recognized as critical factors in the development of atherosclerosis. Healthy dietary patterns, with abundant fruit and vegetable consumption, may prevent the onset of these risk factors due to the presence of phytochemical compounds. Strawberries are known for their high content of polyphenols; among them, flavonoids are the major constituents, and it is presumed that they are responsible for the biological activity of the fruit...



Effect of Chronic Resistance Training on Circulating Irisin: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Irisin seems to play an important role in several chronic diseases, however, the interactions between chronic training and irisin are still unclear. The purpose of this systematic review and meta-analysis was to examine the effect of chronic resistance training on circulating irisin in adults. Literature search was conducted in PubMed, Web of Science and EBSCOhost (Academic Search Complete) until December 2020. Randomized controlled trials researching irisin levels after a resistance training...



International Competition Kinematic Demands in Male Field Hockey

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The objective of this research was to describe kinematic characteristics during international men’s field hockey matches. Sixteen players (age: 25.12±3.66 years; height: 177.12±4.96 cm; weight: 72.45±5.01 kg; caps: 79.12 ±78.96) belonging to the Spanish national team were monitored by means of Global Positioning Systems (GPS) and accelerometry in the course of five matches in the 2017 European Championships. The analyses were performed by game quarter (Q1, Q2, Q3 and Q4), positions (defenders,...

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Differences on Motor Competence in 4-Year-Old Boys and Girls Regarding the Quarter of Birth: Is There a Relative Age Effect?

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The aim of this study was to evaluate the differences on motor competence between boys and girls aged 4 years old and investigate the existence of Relative Age Effect on their motor competence. In total, 132 preschool children were evaluated, of whom 60 (45.50%) were girls and 72 (54.5%) were boys. The distribution of the participants was from quarter 1 [n = 28 (21.2%)], quarter 2 [n = 52 (39.4%)], quarter 3 [n = 24 (18.2%)], and quarter 4 [(n = 28 (21.2%)], respectively. The Movement...

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Relative Age Effect on Motor Competence in Children Aged 4–5 Years

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The purpose of this study was to evaluate whether a Relative Age Effect (RAE) exists in motor competence of preschool children. The hypothesis was that motor competence, assessed by the Movement Assessment Battery for Children-2 (MABC-2), would be higher in preschool children born in the first quarter of the year compared to those who were born in the last quarter of the same year. A total of 360 preschool children were evaluated of whom 208 (57.8%) were boys and 152 (42.8%) were girls, with a...



Validity, Reliability and Reproducibility of OctoBalance Test as Tool to Measure the Upper Limb Compared to Modified-Upper Quarter Y-Balance Test

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The articular evaluation of range of motion (ROM) is currently used to observe imbalance or limitations as possible risk factors or predispositions to suffer future injures. The main aim of this study is to verify the concurrent validity, reliability and reproducibility of the OctoBalance Test (OB) as a valid and reliable tool to measure articular ROM of the upper limb compared to the modified-Upper Quarter Y-Balance Test (mUQYBT). The twenty-five participants were male athletes. All of them...



Most running demand passages of match play in youth soccer congestion period

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The objective of this study was to determine whether there is a decrease in the physical performance of the players in the most demanding passages (MDP) during periods of competition congestion. The study involved 15 under-19 players, belonging to a club in Spain's first division (age: 18.1 ± 0.8 years, weight: 70.2 ± 4.9 kg and height: 1.78 ± 0.06 m), who were monitored during 23 national and international official matches in the 2018/19 season. The Youth League matches were played...

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Effect of the Menstrual Cycle When Estimating 1 Repetition Maximum From the Load-Velocity Relationship During the Bench Press Exercise

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

This study aimed to examine the effect of the ovulatory menstrual cycle (MC) when estimating the 1 repetition maximum (1RM) from the individual load-velocity relationship during the bench press (BP) exercise. Nine resistance-trained eumenorrheic women (age: 28.7 ± 3.6 years) were tested in 3 different phases across the MC: menstrual or early follicular phase (i.e., testing between days 1–3), follicular or late follicular phase (i.e., testing between days 7–10), and luteal or mid-luteal phase (i...

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Strength Training Habits in Amateur Endurance Runners in Spain: Influence of Athletic Level

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

This study determined the strength training (ST) habits of amateur endurance runners in Spain regarding athletic level. A sixteen-item online questionnaire comprised of (i) demographic information, (ii) performance, and (iii) training contents was completed by 1179 athletes. Five group levels were determined according to the personal best times of the athletes in a 10-km trial (LG1: level group 1, 50–55 min; LG2: level group 2, 45–50 min; LG3: level group 3, 40–45 min; LG4: level group 4, 35–40...

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Jump-Rope Training: Improved 3-km Time-Trial Performance in Endurance Runners via Enhanced Lower-Limb Reactivity and Foot-Arch Stiffness

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Context: Plyometric training promotes a highly effective neuromuscular stimulus to improve running performance. Jumping rope (JR) involves mainly foot muscles and joints, due to the quick rebounds, and it might be considered a type of plyometric training for improving power and stiffness, some of the key factors for endurance-running performance. Purpose: To determine the effectiveness of JR during the warm-up routine of amateur endurance runners on jumping performance, reactivity, arch...

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Validity and Reliability of a New Device to Measure Type of Actions in Indoor Sports

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The purpose of this study was to analyze the validity and the reliability of the intensity ranges, number of actions and changes of direction measured by a commercial inertial measurement unit. Eleven elite youth futsal players performed a circuit with different type of displacements as sprinting, running at low-medium intensity, standing up and changes of direction. Data recorded by the Overtraq system were compared with video-analyzer during the six trials of each player. Standard error mean...

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Epidemiology of Injuries in Elite Female Futsal Players: A Prospective Cohort Study

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

njuries are one of the worst case scenarios for an athlete and a team. The aim of this study was to analyze the injury incidence, characteristics and burden among a cohort of elite female futsal players. A prospective cohort study was designed over a season. Eighty-nine players from seven elite female futsal teams were monitored during the whole season. Eight different variables were recorded when an injury happened, as well as exposure time. A total of 90 injuries were recorded so that 54 out...

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Monitoring Workloads of a Professional Female Futsal Team over a Season: A Case Study

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The aims of this study were to describe the external and internal workloads in a professional female futsal team during a whole season and to compare workloads during different periods of the season. Ten professional female futsal players (age 22.8 ± 4.3 years; 5.1 ± 2.4 years of experience; weight 61.9 ± 7.1 kg; height 1.66 ± 0.06 m) participated voluntarily in this study during the whole season. The internal workload was measured by the session-Rate of perceived exertion (session-RPE) method...

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Perceptions of the technical staff of professional teams regarding injury prevention in Spanish national futsal leagues: a cross-sectional study

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Futsal is a sport with increasing popularity and level of performance, both in male and female categories. Also, there are several injuries along a season, so it is needed to know how to reduce this burden. The purpose of this study was to describe the perceptions of technical staff on injury risk factors, risk testing and preventive measures, and the strategies used by them within professional male and female futsal teams. A cross-sectional study was designed during the 2017–2018 season. A...

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Anthropometric and conditional profile in semiprofessional futsal players: differences between sexes. A case study. [Perfil antropométrico y condicional en jugadores semiprofesionales de futbol sala: diferencias entre sexos. Un estudio de caso].

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Anthropometrical profile is one of the indicators associated to optimal performance of futsal players. However, no studies have analyzed these factors in both sexes neither created an anthropometrical profile of each sex. For these reasons, the goals of this study were: to describe and compare the anthropometric and conditional profiles of sub-elite futsal players, and to analyze possible correlations between anthropometric and conditional parameters. 11 female and 8 male sub-elite futsal...

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The Relative Age Effect in Professional Futsal Players

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The objective of this study was to verify the occurrence and effect size of relative age effect in professional futsal players, by observing how its presence and impact change according to the season, team level and player position. The sample was composed of 1873 professional futsal players who played in the First Division of the Spanish National Futsal League between seasons 2006-2007 and 2014-2015. The players’ birthdates were divided into quarters (Q1, Q2, Q3 and Q4). A relative age effect...

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Different race pacing strategies among runners covering the 2017 Berlin Marathon under 3 hours and 30 minutes

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The purposes of this study were 1) to analyse the different pacing behaviours based on athlete's performance and 2) to determine whether significant differences in each race split and the runner's performance implied different race profiles. A total of 2295 runners, which took part in Berlin’s marathon (2017), met the inclusion criteria. 4 different groups were created based on sex and performance. Men: Elite (<02:19:00 h), Top 1 (<02:30:00 h), Top 2 (<02:45:00 h) and Top 3...

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Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

We studied the influence of pregnancy exercise on maternal/offspring cardiometabolic health until delivery and at follow-up. We pooled data from two randomized controlled trials from our group that were performed following the same methodology (one unpublished). We also collected follow-up data de novo from the participants of both trials and their offspring. In total, 1348 women with uncomplicated, singleton gestations were assigned to an intervention (n = 688, performing a supervised,...

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The psychometric properties of the person-centered therapeutic relationship in physiotherapy scale

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Objective To determine the psychometric properties of the Person-Centered Therapeutic Relationship in Physiotherapy Scale (PCTR-PT) in order to find the most appropriate fit for the tool. Methods Patients who had received treatment at the physiotherapy service of nine hospitals in Spain were invited to complete the 31 items of the PCTR-PT scale. To select the most appropriate items of the PCTR-PT, an exploratory factorial analysis (EFA) was performed using the maximum likelihood and oblique...



Analysis of congested schedule on competition external load in field hockey. [Análisis de la carga externa de competición en un periodo de congestión en hockey hierba].

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

This study aimed to investigate the variation in players’ physical demands profile during a major national men fieldhockey tournament which consisted of 3 matches on consecutive days. Ten Spanish National League hockey players participated in the study (age: 24.2 ± 2.6 years; body mass: 74.2 ± 5.7 kg; height 176.8 ± 5.1 cm). Participants´ physical demands were monitored using global positioning system devices (SPI Elite, GPSports). Activity was categorized into total distance (m), relative...



Changes in External Load When Modifying Rules of 5-on-5 Scrimmage Situations in Elite Basketball

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Vazquez-Guerrero, J, Reche, X, Cos, F, Casamichana, D, and Sampaio, J. Changes in external load when modifying rules of 5-on- 5 scrimmage situations in elite basketball. J Strength Cond Res 34(11): 3217–3224, 2020—Constraining tasks are very frequent during the team sports training process; however, most of the effects of these coaching decisions are unknown, which leads to less controlled performing environments, with less chances to promote improvements. The aim of this study was to determine...

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The most demanding passages of play in football competition: a comparison between halves

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The purpose of this investigation was to determine the differences between halves in the most demanding passages of play in football players according to playing position and duration-specific activity.Global positioning system data were collected from twenty-three football players from a reserve squad of the Spanish La Liga. A total of 265 individual match half data were analysed across the competitive season. Players were categorised based on positional groups: full-back (FB), central...



Looking for Complementary Intensity Variables in Different Training Games in Football

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The main aim of this study was to identify which combination of external intensity training load (iTL) metrics capture similar or unique information for different training game (TG) formats and official matches (OMs) in football using principal component (PC) analysis. Ten metrics of iTL were collected from 24 professional male football players using global positioning technology. A total of 348, 383, 120, 127, 148, and 207 individual files for small-sided possession games, medium-sided...

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Positional demands for various-sided games with goalkeepers according to the most demanding passages of match play in football

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The main aim was to determine the differences between four training games and competitive matches (CM) according to position and compared to the most demanding passages (MDP) of competitive match play. Global Positioning System data were obtained from 21 football players belonging to the reserve squad of a Spanish La Liga club during the 2015/16 season. The training games were small-sided games (SSGs) with 5 and 6 and large-sided games with 9 and 10 outfield players per team. The players were...



Demandas cinemáticas de competición internacional en el hockey sobre hierba femenino

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Objetivo. Comparar las demandas cinemáticas de jugadoras internacionales de hockey sobre hierba durante partidos de competición oficial. Material y métodos. Dieciséis jugadoras (edad: 24.7±2.8 años; peso: 57.9±5.9 kg; altura: 165.2±4.9 cm) pertenecientes a la selección absoluta española fueron monitorizadas mediante sistemas de posicionamiento global (GPS) durante 5 partidos del Campeonato de Europa. Los análisis fueron llevados a cabo en función de la demarcación de las jugadoras (defensas,...



Protective Effect of Exercise in Pregnant Women Including Those Who Exceed Weight Gain Recommendations: A Randomized Controlled Trial

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Objective: To investigate the effect of supervised moderate to vigorous exercise on gestational weight gain, its related risks (gestational diabetes [GD]), macrosomia, and type of delivery), and the preventive effects on women who exceed the weight gain recommendations. Patients and methods: We conducted a single-center, 2-armed, randomized controlled trial between October 1, 2009, and June 30, 2011, in which 678 women were assessed and 345 were randomized by a central computer system to an...

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Influence of maternal physical exercise on fetal and maternal heart rate responses

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

This study aims to determine if regular maternal physical exercise leads to measurable adaptations of the fetal autonomic nervous system (fANS) tested by fetal heart rate recovery time. A randomized controlled trial enrolled 131 pregnant women into two study groups, Exercise Group (EG) and Control Group (CG). All participants signed an informed consent, study was approved by the local Clinical Research Ethics Committee. Data was analyzed on 81 participants. EG participants (n = 43) received a...

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Assessment of the external load of amateur soccer players during four consecutive training microcycles in relation to the external load during the official match

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Aim: The aim of this study was to assess the external load of amateur male players during 4 consecutive training microcycles (M) at the beginning of the in-season according to the training session in absolute external load demands and in relation to the competition demands. Methods: Regional-level players (n = 10; age, 20.8 ± 1.7 years; height, 175.5 ± 3.8 cm; body mass, 69.7 ± 2.9 kg; soccer experience, 13.2 ± 2.5 years) were monitored using GPS devices during training sessions and matches....



Acute muscle fatigue and CPR quality assisted by visual feedback devices: A randomized-crossover simulation trial

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Objective To analyse the acute muscular fatigue (AMF) in triceps brachii and rectus abdominis during compression-only and standard cardiopulmonary resuscitation (CPR) performed by certified basic life support providers. Methods Twenty-six subjects were initially recruited and randomly allocated to two study groups according to the muscles analysed; eighteen finally met the inclusion criteria (nine in each group). Both groups carried out two CPR tests (compression-only and standard CPR) of 10...



Jugadores comodines durante diferentes juegos de posición

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

El objetivo de este trabajo fue estudiar las demandas cinemáticas impuestas a los jugadores comodines y regulares, además de comparar la demanda impuesta a los comodines en diferentes juegos de posición (JP; 4v4+3, 5v5+3, 7v7+3 y 8v8+3). La demanda cinemática fue monitorizada a través de dispositivos GPS de 10 Hz. En el estudio participaron 25 jugadores de fútbol (20.5 ± 1.8 años, 178.4 ± 6.6 cm, 69.7 ± 6.1 kg) pertenecientes al equipo filial de un club de 1ª división española durante la...



Effects of Core Strength Training Using Stable and Unstable Surfaces on Physical Fitness and Functional Performance in Professional Female Futsal Players

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The aim of this study was to assess the effect of core strength training performed on a stable surface (CTS) compared with core strength training performed on an unstable surface (CTU) on physical fitness (jump performance, sprint, and repeated sprint ability (RSA)) and quality of movement (Fundamental Movement Screen) in professional female futsal players. Fourteen professional female futsal players (mean age: 23.7 ± 5.1 years, age range: 18-28 years) were randomly assigned to a CTS (n = 7) or...



Positional Comparisons in the Impact of Fatigue on Movement Patterns in Hockey

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Purpose: To examine the influence of the match period on the movement patterns of hockey players according to their playing positions under the introduction of quarters (QTRs). Methods: Sixteen subelite-level Spanish National League male hockey players participated in the study (age: 25.5 [2.9] y; body mass: 74.6 [5.5] kg). Global positioning system devices were used to monitor players’ running performance during 17 competitive matches (113 match-play profiles). Only players who played for at...

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Training intensity distribution and performance of a recreational male endurance runner. A case report

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The polarized training intensity distribution model (PTM) has demonstrated to achieve larger improvements than lactate threshold model (LTM) in elite and well-trained endurance athletes. However, there is a lack of knowledge about the effectivity of PTM with novice recreational runners. This research aimed to compare the impact of LTM vs PTM on a novice recreational runner’s performance. The athlete (age 32 y, body mass 73 kg, height 179 cm, basal HR 43 bpm, Σ6 skinfolds 51.6 mm) trained...

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Practical Active and Passive Recovery Strategies for Soccer Players

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

As a result of training and competition load in soccer, the majority of the body's physiological systems are stressed. To accelerate the recovery process and enhance performance in soccer, different postexercise recovery modes have been suggested and are broadly classified into 2 categories: active recovery or passive recovery. despite the popularity, there is a lack of scientific evidence for the validity of these recovery interventions: This review summarizes the evidence base for using...

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Prehospital Emergency Medicine at the Beach: What Is the Effect of Fins and Rescue Tubes in Lifesaving and Cardiopulmonary Resuscitation After Rescue?

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Objective To analyze the influence of fins and rescue tube use in a water rescue, assessed by time and distance to salvage position, physiological parameters, and cardiopulmonary resuscitation (CPR). Methods Twenty professional lifeguards (10 men, 10 women) conducted 3 tests: a baseline test of 5 minutes of CPR and 2 water rescues, 1 without rescue equipment (NRE), and the other with fins and rescue tube (FRT). They also had to perform 5 minutes of CPR after each rescue. Time and distance of...

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Is Marathon Training Harder than the Ironman Training? An ECO-method Comparison

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Purpose: To compare the absolute and relative training load of the Marathon (42k) and the Ironman (IM) training in recreational trained athletes. Methods: Fifteen Marathoners and Fifteen Triathletes participated in the study. Their performance level was the same relative to the sex's absolute winner at the race. No differences were presented neither in age, nor in body weight, height, BMI, running VO2max max, or endurance training experience (p > 0.05). They all trained systematically...



Heart Rate, Technical Performance, and Session-RPE in Elite Youth Soccer Small-Sided Games Played With Wildcard Players

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The aim of this study was to compare heart rate (HR), rating of perceived exertion (RPE), and technical-tactical actions during small-sided games (SSGs) played without (CTR), with internal (IW), and with IW and external (IEW) wildcard players. A total of 22 young male soccer players (age 17.2 ± 0.9 years) randomly completed six 4vs4 SSG situations. The control conditions occurred with goals scored without goalkeeper (4vs4-NO) and with goalkeeper (4vs4-GK). During the experimental conditions,...

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Reliability and Usefulness of the 30-15 Intermittent Fitness Test in Male and Female Professional Futsal Players

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The purpose of this study was to determine the reliability and usefulness of the 30-15 Intermittent Fitness Test (30-15IFT) in professional male and female futsal players. Thirteen male (24.4 ± 5.6 years; 174.5 ± 10.3 cm; 70.3 ± 9.9 kg) and fourteen female (23.3 ± 4.5 years; 165.8 ± 6.2 cm; 61.7 ± 5.5 kg) professional futsal players performed the 30-15IFT on two occasions, separated by 5 days. Maximal intermittent running velocity (VIFT) and heart rate at exhaustion (HRpeak) data were collected...



Assessing the efficacy of rescue equipment in lifeguard resuscitation efforts for drowning

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Purpose The whole drowning process usually occurs within seconds to a few minutes. An early rescue may stop and/or prevent most medical complications. Fins, rescue tube, and rescue board (RB) are the equipment most frequently used by lifeguards. Our objective was to compare, in a water rescue quasiexperimental trial, these different pieces of rescue equipment to define the safest and with the lower rescue time as well as to assess their effects on the lifeguards' physiological state and...

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The Relationship Between Intensity Indicators in Small-Sided Soccer Games

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The aim of the present study was to examine the relationship between different kinds of intensity indicators in small-sided soccer games. This descriptive correlational study included 14 semi-professional male soccer players (21.3 ± 2.3 years, 174 ± 4.0 cm, 73.4 ± 5.1 kg) from the same team. The players were monitored by means of heart rate monitors and GPS devices during 27 small-sided games of nine different formats, yielding a total of 217 recordings. After each game the Borg scale was used...



Cardiac Parasympathetic Reactivation in Elite Soccer Players During Different Types of Traditional High-Intensity Training Exercise Modes and Specific Tests: Interests and Limits

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Background: The cardiac parasympathetic reactivation is currently used in soccer with a daily or weekly monitoring. However, previous studies have not investigated how this cardiac parasympathetic reactivation is in elite soccer players along different types of traditional high-intensity training exercise and specific tests. In this context, the present study aim to analyse it and to determine the interests and limits of this type of physiological information. Objectives: The present study aims...



Nutritional Value and Preventive Role of Nigella sativa L. and Its Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and Clinical Studies

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

In recent times, scientific attention has been paid to different foods and their bioactive components for the ability to inhibit the onset and progress of different types of cancer. Nigella sativa extract, powder and seed oil and its main components, thymoquinone and α-hederin, have showed potent anticancer and chemosensitizing effects against various types of cancer, such as liver, colon, breast, renal, cervical, lung, ovarian, pancreatic, prostate and skin tumors, through the modulation of...



Links between Nutrition, Infectious Diseases, and Microbiota: Emerging Technologies and Opportunities for Human-Focused Research

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

The interaction between nutrition and human infectious diseases has always been recognized. With the emergence of molecular tools and post-genomics, high-resolution sequencing technologies, the gut microbiota has been emerging as a key moderator in the complex interplay between nutrients, human body, and infections. Much of the host–microbial and nutrition research is currently based on animals or simplistic in vitro models. Although traditional in vivo and in vitro models have helped to...

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Effect of antimony in soils of an Sb mine on the photosynthetic pigments and antioxidant system of Dittrichia viscosa leaves

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Antimony is a toxic element whose concentration in soil and water has been rising due to anthropogenic activities. This study focuses on its accumulation in leaves of Dittrichia viscosa growing in soils of an abandoned Sb mine, and the effect on oxidant/antioxidant systems and photosynthetic efficiency. The results showed leaves to have a high Sb accumulation capacity. The amount of total chlorophyll decreased depending on Sb concentration and of carotenoids increased slightly, with a...

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Phenolic Compounds in Honey and Their Associated Health Benefits: A Review

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

Honey is a natural substance appreciated for its therapeutic abilities since ancient times. Its content in flavonoids and phenolic acids plays a key role on human health, thanks to the high antioxidant and anti-inflammatory properties that they exert. Honey possesses antimicrobial capacity and anticancer activity against different types of tumors, acting on different molecular pathways that are involved on cellular proliferation. In addition, an antidiabetic activity has also been highlighted,...



Polyphenol-rich strawberry extract (PRSE) shows in vitro and in vivo biological activity against invasive breast cancer cells

Repositorio: UNEATLANTICO. Repositorio Institucional de la Universidad Europea del Atlántico

We describe the biological effects of a polyphenol-rich strawberry extract (PRSE), obtained from the “Alba” variety, on the highly aggressive and invasive basal-like breast cancer cell line A17. Dose-response and time-course experiments showed that PRSE is able to decrease the cellular viability of A17 cells in a time- and dose-dependent manner. PRSE effect on cell survival was investigated in other tumor and normal cell lines of both mouse and human origin, demonstrating that PRSE is more...