BUSCADOR RECOLECTA

Dysregulation of cholesterol homeostasis is associated with several pathologies including cardiovascular diseases and neurological disorders such as Alzheimer's disease (AD). MicroRNAs (miRNAs) have emerged as key post-transcriptional regulators of cholesterol metabolism. We previously established the role of miR-7 in regulating insulin resistance and amyloidosis, which represents a common pathological feature between type 2 diabetes and AD. We show here an additional metabolic function of...

AIM: Progression of diabetic nephropathy (DN) is linked to the dysregulated increase of adenosine and altered signaling properties. A major contribution to the maintenance of physiological extracellular adenosine levels relies on cellular uptake activity through plasma membrane nucleoside transporters. Because kidney cells are responsive to insulin, this study aims to determine how DN affects insulin regulation of the equilibrative nucleoside transporter-2 (ENT2). METHODS: Human Podocytes...

Clinical relevance of miRNAs as biomarkers is growing due to their stability and detection in biofluids. In this, diagnosis at asymptomatic stages of Alzheimer ' s disease (AD) remains a challenge since it can only be made at autopsy according to Braak NFT staging. Achieving the objective of detecting AD at early stages would allow possible therapies to be addressed before the onset of cognitive impairment. Many studies have determined that the expression pattern of some miRNAs is...

Introduction: Transplant is the replacement with therapeutic purposes, of organs, tissues or cellular material for others, from a donor who is usually a human, alive or dead. In recent years, transplant organs have been developed by the advances that have occurred with immunosuppressive drugs and medical-surgical technology. Due to the frequency of transplants that are performed today, it is common to find these patients in dental clinics. Objectives: To review the literature on oral...

Law is one of the most necessary and powerful types of intelligence. The future of humanity depends on it. We should connect legal thinking with the actual discussion on intelligence. This article presents an integrative approach that embraces both artificial, institutional and emotional intelligence. We need smart jurists, provided with new forms of thinking and trained to manage a law working increasingly as a net. Key concepts of legal rationality are components of intelligence. Smart...

Objectives: Although the safety of patients has been one of the inherent concerns of dental practice, but because the proposals made in the field of dentistry are few and improperly structured, this paper constitutes an attempt to present a proposal titled "Plan for Dental Health Care Risk Management," promoted by the General Council of Dentists of Spain, including a description of the proposed work methodology. Design: The "risk management plan" proposed in this paper is...

Papillon-Lefevre syndrome is a rare autosomal recessively inherited condition which shows features common to both dentistry and dermatology. This disease is characterized by palmoplantar hyperkeratosis and severe periodon- titis. Therefore both the dentist and the dermatologist should be aware of the same because an early diagnosis of the syndrome can help to preserve the teeth by early institution of treatment, using a multidisciplinary approach. Here we present a case report of Papillon-...

Se describe un caso de hemangioendotelioma grado I, que afectaba a la epífisis humeral superior en una paciente de cincuenta y siete años, presentándose clínicamente como una periartritis escapulo humeral. Se comenta el diagnóstico diferencial y el tratamiento que fué de resección local y sustitución del tercio superior del húmero por una prótesis isoelástica, más radioterapia complementaria. Después de ocho meses no hay evidencia de recidiva local o sistémica, ha desaparecido el dolor y la..., This is a report on a case of Hemangioendothelioma grade I located over the uppe r humeral epiphysis, in a woman aged 57, and mimicing scapulohume - ral periarthitis. The authors detail differential diagnosis and treatment consisting of partial ablation and us e a humeral isoelastic prosthesis as well as complementary radioterapy. After 8 months there is no evidence of local recidives or systemic, no pain, and the function of the limb is acceptable. They emphazise the importance of the...

Purpose: To determine the prevalence of Epstein Barr Virus (EBV) in oral hairy leukoplakia lesions (OHL) in HIV+ Venezuelan patients. Material and Method: In this case study, we evaluated 21 HIV+ adult patients with clinically present OHL lesions, 11 who were undergoing antiretroviral therapy, 10 who were not undergoing therapy and 10 HIV-negative adult patients with hyperkeratotic oral mucosal lesions. All of the subjects were assessed at the Infectious Disease Center, Faculty of Dentistry...

El texto que a continuación publicamos es la transcripción íntegra del artículo titulado HOELDERLIN, aparecido en El Heraldo. Periódico político, religioso, literario y industrial, Madrid, año 1, 1843, número 204, del 14 de marzo (parte literaria), y que unos meses después reprodujo El Siglo Diez y Nueve, México, año 2, 1843, el 25 de junio. Los dos primeros párrafos de este artículo (líneas 1-29), han sido publicados ya por Adolf Beck en Hölderlin, Sämtliche Werke, Stuttgart, 1977, (RW,34a). 1...

Se suele decir que para Nietzsche la verdad no existe, y se remite al famoso texto de Sobre verdad y mentira en sentido extramoral; detrás de tal «lectura» suelen estar o el relativismo o el cientismo ambientes. Se trata de un abuso interpretativo. Nietzsche corrige la noción de verdad, desmontando la pretensión de que tengamos acceso a las cosas en sí, a la realidad tal cual. Pero nos hace ver el origen individual de la verdad, la relación entre la experiencia vital y la palabra, por medio de...

Capitulo de libro en una editora Holandesa, En Holandes: Compassie is al meer dan 2500 jaar een belangrijk element van contemplatieve en spirituele tradities (Rahula, 1969), waarvan het boeddhisme waarschijnlijk de bekendste is. De dalai lama (1995, 2000) definieert compassie als ‘een gevoeligheid voor het lijden van jezelf en de ander, in combinatie met een diepgewortelde bereidheid om te proberen het te verlichten’. Niettemin is het bestuderen ervan door westerse onderzoekers een relatief nieuw fenomeen. Pas de laatste 20 jaar zien we...

Se comentan los hallazgos de varias especies de plantas vasculares detectadas en el territorio de la Comunidad Valenciana, especialmente la provincia de Valencia, proponiéndose algunas combinaciones nomenclaturales nuevas.

Si la intución de vincular a Shakespeare con el mundo de los emblemas fue rastreada por la crítica anglosajona desde antiguo, dando lugar a estudios extensos y minuciosos, no ha sido así con la obra de Cervantes. De hecho, no podemos hablar en rigor de unos primeros —y aún tímidos— análisis de este enlace hasta principios de los años ochenta del siglo pasado, y habrá que esperar a que acabe prácticamente el siglo para contar con una mínima bibliografía dedicada. Sin duda, la multiplicación de...

-

The dataset revolves around the nomenclature of thesis supervisors at a global level. It comprises 55 distinct labels originating from 116 countries and spanning across 47 different languages. The data collection process involved extracting information from university websites, official institutions, and doctoral thesis repositories

Después de su salida de Amberes, Benito Arias Montano (ca. 1525/27-1598) mantuvo una frecuente correspondencia con la oficina tipográfica de Cristóbal Plantino. Las cartas no se limitaron a intercambiar noticias públicas y privadas; el teólogo español envió muy a menudo listas de títulos de libros que él o su cenáculo de humanistas sevillanos estaban interesados en comprar. Este artículo se centra en quince listas enviadas entre 1585 y 1596 y conservadas en el Museo Plantin-Moretus de Amberes....

Coordinador del projecte: Universitat de Girona; Autoria: Bea Sándor; Adaptació a l'espanyol: Núria Sadurní, Beatriz San Román, Jose Antonio Langarita, Marisela Montenegro, Pilar Albertín i Joan Pujol; Disseny gràfic: Zsolt S. Szabó; Adaptació gràfica de la guia: Cristina de Dios, This handbook was created within the framework of the Diversity and Childhood: Changing social attitudes towards gender diversity in children across Europe (DaC) project. As its main expected results, the project seeks to raise awareness and reduce prejudice, as well as to improve protection against violence and support for LGBTI+ and gender non-conforming children and youth.1 DaC also aims to provide effective tools to stakeholders and envisages strengthening the well-being and the..., Este manual ha sido elaborado en el marco del proyecto de Diversity and Childhood: Cambiando las actitudes sociales hacia la diversidad de género en la infancia en toda Europa (DaC). Dicho proyecto trata de sensibilizar y reducir los prejuicios, así como de mejorar los mecanismos de protección contra la violencia hacia la infancia y la adolescencia LGTBI+. El proyecto DaC también tiene como objetivo proporcionar instrumentos eficaces a las profesionales, 1 fortalecer el bienestar y los..., Projecte "Diversity and childhood: changing social attitudes towards gender diversity in children across Europe", finançat pel Programa de Drets, Igualtat i Ciutadania (2014-2020) de la Unió Europea (REC-RDAP-GBV-AG-2018-856680)

Frequently Asked Questions about violence against LGBTI+ children for Interactive App in English, Hungarian, Dutch, Croatian, Polish, Greek, Lithuanian, Portuguese, Slovenian, and Spanish, Projecte "Diversity and childhood: changing social attitudes towards gender diversity in children across Europe", finançat pel Programa de Drets, Igualtat i Ciutadania (2014-2020) de la Unió Europea (REC-RDAP-GBV-AG-2018-856680)