BUSCADOR RECOLECTA

[Background] Recently, an effective testis culture method using a gas-liquid interphase, capable of differentiate male germ cells from neonatal spermatogonia to spermatozoa has been developed. Nevertheless, this methodology needs deep analyses that allow future experimental approaches in basic, pathologic and/or reprotoxicologic studies. Because of this, we characterized at cellular and molecular levels the entire in vitro spermatogenic progression, in order to understand and..., [Methods] Testicular explants of CD1 mice aged 6 and 10 days post-partum were respectively cultured during 55 and 89 days. Cytological and molecular approaches were performed, analyzing germ cell proportion at different time culture points, meiotic markers immunodetecting synaptonemal complex protein SYCP3 by immunocytochemistry and the relative expression of different marker genes along the differentiation process by Reverse Transcription - quantitative Polymerase Chain..., [Results] The method promoted and maintained the spermatogenic process during 89 days. At a cytological level we detected spermatogenic development delays of cultured explants compared to the natural in vivo process. The expression of different spermatogenic stages gene markers correlated with the proportion of different cell types detected in the cytological preparations., [Conclusions] In vitro progression analysis of the different spermatogenic cell types, from both 6.5 dpp and 10.5 dpp testes explants, has revealed a relative delay in relation to in vivo process. The expression of the genes studied as biomarkers correlates with the cytologically and functional detected progression and differential expression identified in vivo. After a first analysis of deep sequencing data it has been observed that as long as cultures progress, the proportion..., This work was supported by the Ministerio de Industria Economía y Competitividad (grant number BFU2013–42164-R), Spain., We also thank the support of the publication fee by the CSIC Open Access Publitacion Support Initative through its Unit of Information Resources for Research (URICI TC0000100)., Peer reviewed

Este trabajo se inscribe dentro del Proyecto de Investigación «Digital “Música Poética”. Base de datos integrada del Teatro Clásico Español» (FFI2015-65197-C3-2-P) (MINECO/FEDER, UE)., El documento contiene el tono humano a cuatro voces titulado “Hermosa zagala” del compositor Carlos Patiño. Se ofrece el texto poético de Francisco de Borja y Aragón, Príncipe de Esquilache, debidamente puntuado, la partitura con la transcripción musical a notación moderna y varios datos de interés musical y musicológico., Consejo Superior de Investigaciones Científicas (CSIC). Universitat de Barcelona (UB), No

14 páginas.- Ilustraciones.- © The authors 2017. Open Access under Creative Commons by Attribution Licence. Use, distribution and reproduction are unrestricted. Authors and original publication must be credited., Over the past decades, the altitudinal and latitudinal advance of forest lines has increased due to global warming and the abandonment of less productive areas previously subject to agricultural activities. The intensity and speed of the forest line advance also depend on numerous physical, biological and human factors that are region-specific. It is important to fully understand the mechanisms behind forest line behaviour, as existing studies do not report global figures. We selected 4 study..., This article is based on work from COST Action ES1203 SensFor, supported by COST (European Cooperation in Science and Technology, www.cost.eu)., Peer reviewed

Este artículo contiene 4 páginas, 2 tablas., Few studies to date have examined the effect of the high temperatures attained during wildfire events on the pigments present in forest foliage. Here, we seek to analyse the main photosynthetic pigments in the leaves of the oak, cork oak and eucalyptus following a wildfire. We also subject leaves of these last two species to a range of contact temperatures (100e500 C) in the laboratory using a muffle furnace. The samples were left in the muffle for two hours at 100, 150, 200, 250, 300, 350,..., This work was supported by POSTFIRE Project (CGL2013-47862- C2-1 and 2-R) and POSTFIRE_CARE Project (CGL2016-75178-C2-2- R) sponsored by the Spanish Ministry of Economy and Competitiveness and AEI/FEDER, UE., Peer reviewed

87 Pags.- 3 Tabls.- 5 Figs.- 1 Suppl. Fig.- 5 Suppl. Tabls. The definitive version is available at: http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1744-7348, The nature and structure of genetic diversity in the Spanish apple germplasm preserved at the national level was widely unknown, since studies performed to date on this topic have been exclusively carried out at the regional scale. Here, 1453 accessions from Spanish collections of Malus × domestica were evaluated with a common set of 13 SSR (Simple Sequence Repeats) markers in order to estimate genetic diversity, to identify the underlying genetic structure and to unravel the relationships..., This work was supported by INIA (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria), under the Project: 'Harmonization of the methodology of characterization, assessment of genetic diversity and definition of the core collection of the apple germplasm conserved in Spanish genebanks (ref. RF2011-00017-C05)'., Peer reviewed

The present invention refers to the use of sodium channel blockers such as tetrodotoxin or saxitoxin, its analogues/derivatives as well as their acceptable salts, for the production of a medicament for the treatment of preterm labor and/or premature birth., Peer reviewed, Wex Pharmaceuticals Inc., A1 Solicitud de patente con informe sobre el estado de la técnica

The present invention refers to the use of sodium channel blockers such as tetrodotoxin or saxitoxin, its analogues/derivatives as well as their acceptable salts, for the production of a medicament for the treatment of preterm labor and/or premature birth., Peer reviewed, Wex Pharmaceuticals Inc., A1 Solicitud de patente con informe sobre el estado de la técnica

El Instituto de Síntesis Química y Catálisis Homogénea (ISQCH) (centro mixto CSIC-UNIZAR), el Departamento de Química Inorgánica y la Facultad de Ciencias de la Universidad de Zaragoza, homenajean el próximo 27 de noviembre al Profesor Luis A. Oro con motivo de su 70 cumpleaños y su nombramiento como Profesor Emérito., Peer Reviewed

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New spirolactams of formula (I) having a benzodienone moiety and a azetidinone moiety which are highly stable due to pi interactions. They are useful as UV absorbers and as synthetic intermediates., Peer reviewed, Laboratorios del Dr. Esteve S.A., A1 Solicitud de patente con informe sobre el estado de la técnica

Entrevista al Catedrático Juan Forniés., Peer Reviewed

Los institutos ICMA, Instituto de Ciencia de Materiales de Aragón, e ISQCH, Instituto de Síntesis Química y Catálisis Homogénea, organizan la exposición >Un Universo de Luz> que estará expuesta del 26 al 28 de octubre de 2015 en el Edificio Betancourt de la Escuela de Ingeniería y Arquitectura de la Universidad de Zaragoza., Peer Reviewed

Nuevas espirolactamas que presentan un agrupamiento benzodienona y un agrupamiento azatidinona, y que son altamente estables gracias a interacciones pi. Presentan utilidad como absorventes UV y como intermedios sintéticos., Peer reviewed, Laboratorios del Dr. Esteve S.A., B1 Patente sin examen previo

New spirolactams of formula (I) having a cycloexadienone moiety which are highly stable due to pi interactions between the W group and the dienone moiety. They are useful as UV absorbers and as intermediates for the synthesis of active biomolecules., Peer reviewed, Laboratorios del Dr. Esteve S.A., A1 Solicitud de patente con informe sobre el estado de la técnica

Desde 2004 un equipo hispano-sirio-libanés ha desarrollado un proyecto de investigación arqueológica al oeste de la ciudad de Homs, en la República árabe de Siria. Las instituciones implicadas son la Institución Milà y Fontanals (Departamento de Arqueología y Antropología) del CSIC y el Instituto Internacional de Investigaciones Prehistóricas de la Universidad de Cantabria, por la parte española, la Universidad Saint Joseph de Beirut, por la libanesa, y la Dirección General de Antigüedades y..., Peer Reviewed

Moderation poses one of the main Internet challenges. Currently, many Internet platforms and virtual communities deal with it by intensive human labour, some big companies-such as YouTube or Facebook-hire people to do it, others-such as 4chan or fanscup-just ask volunteer users to get in charge of it. But in most cases the policies that they use to decide if some contents should be removed or if a user should be banned are not clear enough to users. And, in any case, typically users are not..., Work funded by Spanish National project CollectiveWare code TIN2015-66863-C2-1-R (MINECO/FEDER)., Peer Reviewed

New spirolactams of formula (I) having a cycloexadienone moiety which are highly stable due to pi interactions between the W group and the dienone moiety. They are useful as UV absorbers and as intermediates for the synthesis of active biomolecules., Peer reviewed, Laboratorios del Dr. Esteve S.A., A1 Solicitud de patente con informe sobre el estado de la técnica

Seminario científico del 15 al 18 de Marzo de 1983, Cádiz.-- 38 pages, 18 figures, Peer reviewed

Resumen de la Conferencia impartida en el Ciclo de Conferencias Encuentros con la Ciencia, celebrada el 9 de marzo de 2017., Como ya registró Aristóteles “algunas cosas no tienen fuego de ningún tipo, aun así parecen producir luz”. Este y otros fenómenos terminaron llamándose luminiscencia. De modo que esta propiedad no es una revolución tecnológica de nuestro tiempo, aunque está recibiendo una enorme atención por sus recientes aplicaciones. Algunas de estas aplicaciones sí que son una revolución tecnológica importante, como se plasma en que dos (o tres, según se mire) premios nobel recientes, tanto de Física como de..., No

Eliminar los compuestos de azufre de los combustibles mediante el empleo de agua oxigenada. Este es el planteamiento de un prometedor sistema catalítico heterogéneo, ‘made in Aragón’, que podría minimizar los efectos perjudiciales de los combustibles sobre la salud y el medio ambiente. Este desarrollo, realizado en el ISQCH en colaboración con la empresa productora de agua oxigenada Peroxychem Spain, ubicada en La Zaida, es uno de los artículos científicos de ingeniería química más citados del..., No

154 p.-47 fig., [EN] As replication proceeds DNA replication intermediates (RIs) undergo topological changes that affect supercoiling, catenation and knotting. Nevertheless, the function and dynamics of these changes remain to be fully understood. In this context, the role of DNA replication knots in prokaryotes remains a mystery. DNA knots are very harmful for cells if not removed efficiently. However, sister chromatids become knotted in vivo. To identify the enzyme responsible for knotting and to study inter..., [ES] Durante la replicación del DNA, los intermediarios de replicación (RIs) sufren cambios topológicos que afectan al superenrollamiento, encadenamiento y anudamiento. Los nudos en el DNA tienen consecuencias deletéreas y deben ser eliminados; por ello el papel del anudamiento de las cromátidas hermanas in vivo en procariotas continua siendo un misterio. Para estudiar esos nudos inter-cromátida y tratar de identificar la enzima responsable de anudar las cromátidas hermanas, construimos..., Financiación concedida por el Ministerio de Ciencia e Innovación a través del Proyecto BFU2008-00408 y del programa de becas de formación de personal universitario., Peer reviewed

17 pages, 8 figures, Peer Reviewed

Entrevista a Concepción Gimeno., La investigadora aragonesa Concepción Gimeno, del Instituto de Investigación de Síntesis Química y Catálisis Homogénea (ISQCH), ha sido reconocida como una de las 12 mejores químicas del mundo en los premios Mujer Distinguida en Química de 2017, que concede cada dos años la Unión Internacional de Química Pura y Aplicada (IUPAC)., No

141 p.-36 fig.-1 tab., [EN] How DNA replicates is a critical question to understand life. The replication process is very complex and is highly regulated. Many molecules are implicated in this process which is not fully characterized. In this Doctoral Thesis, we tried to improve the knowledge about replication using different approaches. Nowadays, in the scientific community, there is not a consensus as to whether or not swiveling of the replication fork and formation of pre-catenanes can occur in vivo. In the first..., In a second part, we studied different characteristics about replication fork barriers (RFBs). These barriers are in the rDNA of all eukaryotic organisms and they are very important for the cells because in the rDNA transcription and replication occur at the same time. If there would be no RFBs, the replication and transcription machineries could collide. RFBs block those replication forks moving in the opposite direction to transcription. We investigated and quantified the efficiency of RFBs..., [ES] Comprender cómo replica el DNA es una cuestión crítica para entender la vida. La replicación del DNA es un proceso muy complejo y altamente regulado, en el que están implicadas una gran cantidad de moléculas. Hoy por hoy, este proceso no está plenamente caracterizado. En la presente Tesis Doctoral se ha intentado profundizar en la comprensión de la replicación del DNA utilizando diferentes aproximaciones a lo largo de sus distintas etapas. Actualmente no existe un consenso entre los..., La replicación del rDNA ocurre mientras estos genes son transcripcionalmente activos. Por tanto, si una horquilla de replicación intenta atravesar una unidad de rDNA en la dirección opuesta a la transcripción, el complejo de replicación podría colisionar con el de transcripción, pudiendo tener consecuencias letales para la célula. Para estudiar dichas barreras se han utilizado varios minicromosomas artificiales de levaduras, a los cuales se les clonaron distinto número de RFBs. Se transformaron..., Financiación concedida por el Ministerio de Economía y Competitividad a través de los proyectos BFU2011-22489 y BFU2014-56835, Peer reviewed

12 páginas, 4 figuras, 2 tablas.-- Melina Abdou ... et al., Platinum Group Elements (PGEs) are extremely scarce in the Earth's Crust and of strong interest for high-end technologies due to their specific properties. They belong to the Technology Critical Elements (TCEs) for which use is forecast to increase, implying growing emissions into the environment in the following years. In particular, with the intensive use of platinum (Pt) in car catalytic converters, the anthropogenic geochemical cycle of this element has surpassed the natural cycle. Yet..., This work has benefited from the support by the FEDER Aquitaine-1999-Z0061, the Agence de l'Eau Adour-Garonne32022123 and 31033111, the COST Action TD1407, and the EU FP7 Ocean 2013.2 Project SCHeMA (Project-Grant Agreement 614002), which is gratefully acknowledged. M. Abdou has benefited of an IdEx University of Bordeaux mobility grant, Peer reviewed

Entrevista a María Concepción Gimeno., La IUPAC ha reconocido a la española María Concepción Gimeno como una de las 12 químicas más destacadas del mundo. La investigadora aragonesa trabaja en el desarrollo de compuestos con aplicación en nuevas tecnologías y en el ámbito médico., No

10 pages, 12 figures, 3 tables, Peer Reviewed

Trabajo presentado en el Ramon Margalef Summer Colloquia, celebrado en Barcelona del 7 al 18 de julio de 2014., No

Trabajo presentado en el Workshop on Action, Vision and Language and their Brain Mechanisms in Evolutionary Relationship, celebrado en Los Angeles del 27 al 29 de enero de 2014., No

The development of rapid and accurate techniques to predict the composition of crude bio-oils obtained via the pyrolysis of lignocellulosic biomass is a prerequisite for their industrial implementation. Here, we demonstrate the potential of the Fourier Transform Infrared Spectroscopy to replace the gas chromatography-mass spectrometry (GC-MS) in determining the compositional groups of bio-oils. Using mid-infrared spectroscopic technique as predictor, chemometric tools based on partial least..., Authors would like to thank the Spanish MINECO and European Union FEDER funds for providing support for this work (projects CTQ2012-37984-C02-01 and ENE2015- 68320-R). B.P. thanks the Spanish Ministry of Education through the Temporary Transfer Program (TRA13/00003)., Peer reviewed

13 pages, 7 figures, 2 tables, Peer Reviewed

1 poster presented at the 47th West European Fish Technologists Association Conference, Aviva Stadium, Dublin, 9th-12th October 2017, No

17 pages, 3 figures, 4 tables, Peer Reviewed

14 pages, 3 figures, 9 tables, Peer Reviewed

Trabajo presentado en el Workshop on Action, Vision and Language and their Brain Mechanisms in Evolutionary Relationship, celebrado en Los Angeles del 27 al 29 de enero de 2014., No

El jueves 27 de abril termina la exitosa segunda temporada de “De copas con ciencia”. De copas con ciencia es una iniciativa de los institutos de investigación, ICMA (Instituto de Ciencia de Materiales de Aragón) e ISQCH (Instituto de Síntesis Química y Catálisis Homogénea) ambos centros mixtos CSIC – Universidad de Zaragoza, que pretende saciar la curiosidad científica de la población en general de un modo distendido, ameno y divertido en el tiempo de ocio acercándola a los bares. La actividad..., No

18 pages, 10 figures, 3 tables, Peer Reviewed

15 pages, 1 figure, 4 tables, Peer Reviewed

20 pages, 14 figures, 5 tables, Peer Reviewed

29 pages, 6 figures, 9 tables, Peer Reviewed

Las dehesas son sistemas agro-forestales en los que se producen complejos mecanismos de intercambio de carbono y agua debido a la presencia de estratos de vegetación diferenciados (pastizal, arbolado y matorral), en un marco climático caracterizado por periodos de sequía. Dichos componentes no se dan en las mismas proporciones constituyendo complejos mosaicos en función del tipo de manejo, la densidad del arbolado y el momento de año. En este contexto, una de las variables clave en la..., Este trabajo se ha realizado en el marco del proyecto FLUXPEC (CGL2012-34383) financiado por el Ministerio de Economía y Competitividad. Los autores también agradecen la financiación de la investigación predoctoral de Lidia Vlassova por parte de SENESCYT-Ecuador., Peer reviewed

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The infection of humans by lethal pathogens such as Ebola and other related viruses has not been properly addressed so far. In this context, a relevant question arises: What can chemistry do in the search for new strategies and approaches to solve this emergent problem? Although initially a variety of known chemical compounds-for other purposes-proved disappointing in tests against Ebola virus (EBOV) infection, more recently, specific molecules have been prepared. In this Perspective, we..., Peer Reviewed

Canals, Miquel ... et. al.-- Mediterranean Targeted Project (MTP) - EUROMARGE-NB Project, Contract MAS2-CT93-0053, Synthesis of Final Results.-- 38 pages, 21 figures, 4 tables, Peer Reviewed

Este artículo contiene 13 páginas, 8 figuras, 2 tablas., Recent outbreaks of Zika, chikungunya and dengue highlight the importance of better understanding the spread of disease-carrying mosquitoes across multiple spatio-temporal scales. Traditional surveillance tools are limited by jurisdictional boundaries and cost constraints. Here we show how a scalable citizen science system can solve this problem by combining citizen scientists’ observations with expert validation and correcting for sampling effort. Our system provides accurate early warning..., A. Torrell (Departament de Territori i Sostenibilitat, Generalitat de Catalunya) and the support of the Spanish Ministry of Public Health, CCAES (Centro de Coordinación de Alertas y Emergencias Sanitarias) and the Health Department of the Generalitat de Catalunya. J.R.B.P. is funded by the European Union’s Horizon 2020 research and innovation programme under Marie Skłodowska-Curie grant agreement no. 657956. The research leading to these results has received funding from the Spanish Ministry of..., Peer reviewed

Mediterranean Targeted Project (MTP) - EUROMODEL II Project, Contract MAS2-CT93-0066, Synthesis of Final Results.-- 33 pages, 4 figures, Peer Reviewed

[EN] Recent studies about the Neolithic occupations in the area of the Strait of Gibraltar are having a renewed interest. We believe there were contacts between tribal societies of both borders. The Cave of Benzú (Ceuta) is being excavated from year 2002 by an interdisciplinary group of investigators belonging to the University of Cadiz, and others universities and centers. We contributed in this work new features in the use wear analysis of the líthic technology and in the analysis of the..., [ES] El estudio de las ocupaciones neolíticas en el área del Estrecho de Gibraltar está alcanzando un renovado interés. Nosotros creemos que había contactos entre las sociedades tribales de ambas orillas. La Cueva de Benzú (Ceuta) está siendo excavada desde el año 2002 por un equipo interdisciplinar de investigadores de la Universidad de Cádiz, y otras universidades y centros. Aportamos en este trabajo novedades al estudio funcional de la tecnología lítica y al análisis de los fi tolitos. Los..., Peer Reviewed

La invención proporciona azetidinonas espirocondensadas sumamente funcionalizadas que tienen un resto ciclohexano con el número deseado de grupos hidroxilo protegidos o sin proteger, que se introducen con alta estereo y regioselectividad, así como procedimientos para su obtención., Peer reviewed, Laboratorios del Dr. Esteve S.A., A1 Solicitud de patente con informe sobre el estado de la técnica

La invención proporciona azetidinonas espirocondensadas sumamente funcional izadas que tienen un resto ciclohexano con el número deseado de grupos hidroxilo protegidos o sin proteger, que se introducen con alta estereo y regioselectividad, así como procedimientos para su obtención., Peer reviewed, Laboratorios del Dr. Esteve S.A., B1 Patente sin examen previo

The invention provides highly functionalised spiro-fused aZetidinones having a cycloheXane moiety With the desired number of protected or unprotected hydroXyl groups Which are introduced With high stereo and regioselectivity, as Well as processes for obtaining the compounds., Peer reviewed, A1 Solicitud de patente con informe sobre el estado de la técnica

The present invention refers to highly functionalised spirofused azetidinones of fomula I (formula) having a cyclohexane moiety with the desired number of protected or unprotected hydroxyl groups which are introduced with high stereo and regioselectivity, as well as processes for their synthesis., Peer reviewed, Laboratorios del Dr. Esteve S.A., B2 Patente con examen previo

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Mediterranean Targeted Project (MTP) - MEDIPELAGOS Project, Contract MAS2-CT93-0063, Synthesis of Final Results.-- 12 pages, 1 figures, Peer Reviewed

El grupo de investigación liderado por el Prof. Mariano Laguna del ISQCH junto con la empresa aragonesa WIREC (WEEE International Recycling, S.L.) de Villanueva de Gállego, trabajan en el desarrollo de una estrategia de reciclaje que permita la recuperación de los elementos que componen las kesteritas teniendo en cuenta la optimización de los costes y la escalabilidad del proceso a nivel industrial., No

El juego “Hi Score Science - una app para aprender jugando” ha recibido el primer premio en la XVIII Edición del programa de Ciencia en Acción en la modalidad “Materiales Didácticos de Ciencias en Soporte Interactivo” (Premio IBM). La entrega del galardón tendrá lugar en el Certamen Final el 8 de octubre de 2017 en el Teatro Coliseo de Eibar. La app, desarrollada por dos centros de investigación el Instituto de Síntesis Química y Catálisis Homogénea, ISQCH, y el Instituto de Ciencia de..., No

Trabajo presentado en la International Conference "Archaeology and Heritage Management at World Heritage Sites; Social and Economic Involvements", celebrada en Berlín del 16 al 18 de octubre de 2017., In this paper we aim to propose certain ideas for an alternative management regime for a heritage site at risk: the cave of Altamira. The cave, located in the north of the Iberian Peninsula, hosts a valuable collection of rock art: “Bison, horses, deer, hands and mysterious symbols were painted or engraved during the millennia when the cave of Altamira was inhabited, between 36,000 and 13,000 years ago. These representations are spread throughout the cave, [but] are concentrated in the..., This project has been funded with support from the European Commission., No

Concurso adopta tu molécula., ¿Qué tienen en común la Semana Santa, el químico Willian Perkin y Steven Spielberg? He dicho bien: Spielberg, no Mel Gibson. La culpa de que ahora mismo os devanéis los sesos la tienen unos caracoles marinos que recogían los fenicios hace unos 3.500 años. Bueno, en realidad la tengo yo, vuestra moleculica de abril. Conocer mi historia os ayudará a descubrirme, como hizo Santiago Sarasa al desenmascarar a la polivalente adenosina y ganar la última edición de ‘Adopta tu Molécula., No

11 pages, 3 annexes, Peer Reviewed

The invention provides highly functionalised spiro-fused lactams of formula (1) having a cyclohexane moiety with the desired number of protected or unprotected functional groups or carbonated structures, which are introduced with high stereo and regioselectivity, as well as processes for their obtention. These compounds are useful for the synthesis of a broad range ofbioactive molecules, such as condoritols and aminoinositols and their analogues., Peer reviewed, Laboratorios del Dr. Esteve S.A., A1 Solicitud de patente con informe sobre el estado de la técnica

The invention provides highly functionalised spiro-fused lactams of formula (1) having a cyclohexane moiety with the desired number of protected or unprotected functional groups or carbonated structures, which are introduced with high stereo and regioselectivity, as well as processes for their obtention. These compounds are useful for the synthesis of a broad range of bioactive molecules, such as condoritols and aminoinositols and their analogues., Peer reviewed, Laboratorios del Dr. Esteve S.A., A1 Solicitud de patente con informe sobre el estado de la técnica

The aim of this study is twofold: to make a geological interpretation of available ground gravity and high resolution airborne magnetic surveys carried out over the Dominican Republic, and to define the spatial limits of key tectonic units of the Central Cordillera. Potential fields and petrophysical data allow the establishment of the spatial limits and the relationships of the key tectonic units at local and regional scale. Therefore, gravity and magnetic data have been integrated to produce..., This study is a follow up of mapping projects K and L financed by SYSMIN program from the European Union., Peer reviewed

The subject of this chapter is the application of models for social coordination (M4SC). Deriving from and extending multiagent systems (MAS), applications of M4SC inherit the attributes of MAS, such as multiple actors, distribution, and heterogeneity, but bring characteristics of their own that are essential to social coordination over and above conventional MAS. In this chapter, we first discuss these differentiating properties of M4SC, identifying essential and non essential (but commonly..., Peer Reviewed

A nomenclatural study on the names of the narrow-leaved plantains linked to Plantago holosteum is presented. The names P. carinata, P. gerardii, P. holosteum, P. maritima var. apennina, P. subulata sensu Wulfen, and P. wulfenii have been studied. The name P. holosteum is lectotypified on illustration by Bauhin & Cherler, P. wulfenii by Willdenow on a specimen preserved at B while P. maritima var. apennina was neotypified using a specimen deposited at RO. For P. holosteum, an accepted and..., ES-TAF-6610, Peer reviewed

En Ruta con ciencia por la magia y el humor - Proyecto de Copas con Ciencia: Programa 40 de Aragón televisión., No

En Ruta con la ciencia, programa 40 de Aragón televisión., No

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At least 95 species of Pamphagidae belonging to 17 genera are known in North Africa. Taxonomic status is fairly known, with some exception, mainly due to scarcity of available specimens of some genera in museums and collections. In this paper, the author proposes a new key to genera and reports the annotated list of all the known species, based on specimens examined in different European museums. Concerning the subfamily Thrinchinae, he proposes to consider only the following species of the..., This research received support from the Synthesys Project (http://www.synthesys.info/) which is financed by European Community Research Infrastructure Action under the FP7 “Capacities” Programme at the Museo Nacional de Ciencias Naturales of Madrid (CSIC)., Peer reviewed

Wie manches beginnt auch die Systematik der Blattarien mit Linné (1758). Er errichtete nämlich die Gattung Blatta mit 9 Arten, die heutzutage zu ebenso vielen verschiedenen Gattungen gerechnet werden. Es sind : Blaberus giganteus (L.), Polyphaga aegyptiaca (L.), Pycnoscelus surinamensis (L.), Periplaneta americana (L.), Panchlora nivea (L.), Arenivaga (Psammoblatta) africana (L.), Blatta orientalis L., Ectobius lapponicus (L.) und Pseudomops oblongata (L.). Die zehnte Art, nämlich Therea..., Peer reviewed

This research has been partially supported by the 2014-SGR-118 grant from the Generalitat de Catalunya., Peer Reviewed

The protein anosmin-1, coded by the KAL1 gene responsible for the X-linked form of Kallmann syndrome (KS), exerts its biological effects mainly through the interaction with and signal modulation of fibroblast growth factor receptor 1 (FGFR1). We have previously shown the interaction of the third fibronectin-like type 3 (FnIII) domain and the N-terminal region of anosmin-1 with FGFR1. Here, we demonstrate that missense mutations reported in patients with KS, C172R and N267K did not alter or..., Peer reviewed, Peer Reviewed

Oligodendrocyte precursor cells (OPCs) originate in specific areas of the developing central nervous system (CNS). Once generated, they migrate towards their destinations where they differentiate into mature oligodendrocytes. In the adult, 5-8% of all cells in the CNS are OPCs, cells that retain the capacity to proliferate, migrate, and differentiate into oligodendrocytes. Indeed, these endogenous OPCs react to damage in demyelinating diseases, like multiple sclerosis (MS), representing a key..., Peer Reviewed

Otamendi fortlet is located in Buenos Aires province (Argentina) and was occupied from 1858 to 1869. Previous archaeological research has yielded large quantities of artefacts from the site; the present study focuses on firearms and related material. The aim of this project is to identify and characterize the firearms to establish their function, place of origin and chronology. They are compared to the archaeological record of Minaña fortlet to understand the diversity of armament technology in..., Peer Reviewed

Peer Reviewed

Entrevista a Fernando Lahoz en el programa Ágora de Radio Aragón., No

[EN] Prehistoric use of fish as a resource has been documented in many sites of different chronology. However the study of use-wear originated by fish processing as well as experimental studies on this subject have not been very common. The present work illustrates the results o fan experimental program carried out on experimental flint artifacts and which aim was to identify the characteristics of the use wears originated by the different activities related to the processing of fish: descaling..., [ES] El consumo de pescado en la prehistoria ha sido registrado en numerosos yacimientos de diversas cronologías. Sin embargo a nivel funcional el procesado de pescado no ha sido generalmente identificado en los instrumentos analizados y tampoco ha sido objeto de estudio recurrente en la mayoría de programas experimentales. En este trabajo presentamos los resultados de un programa experimental realizado con instrumentos experimentales de sílex y orientado a identificar los diversos rastros de..., Este trabajo se inserta dentro del Proyecto I+D+I (HAR2008-04461/HIST): Recursos olvidados en el estudio de grupos prehistóricos: el caso de la pesca en sociedades meso-neolíticas de la llanura rusa. Financiado por Ministerio de Ciencia e Innovación (MCI) del gobierno de España., Peer Reviewed

Entrevista a Mariano Laguna en el programa Ágora de Radio Aragón., No

There are numerous studies describing the signaling mechanisms that mediate oligodendrocyte precursor cell (OPC) proliferation and differentiation, although the contribution of the cellular prion protein (PrP c) to this process remains unclear. PrP c is a glycosyl-phosphatidylinositol (GPI)-anchored glycoprotein involved in diverse cellular processes during the development and maturation of the mammalian central nervous system (CNS). Here we describe how PrP c influences oligodendrocyte..., Peer Reviewed

El proyecto europeo STARCELL de Horizonte 2020 tiene como objetivo la sustitución de dos materias críticas utilizadas en las tecnologías fotovoltaicas y su optimización mediante la introducción de materiales de kesteritas abundantes en la tierra. La inciativa, en la que participa el Instituto de Síntesis Química y Catálisis Homogénea y el grupo WIREC, ambos en Zaragoza, cuenta con un presupuesto total de 6,2 millones de euros., No

2 p., Peer reviewed

Entrevista a María Concepción Gimeno., M. Concepción Gimeno trabaja desde hace 25 años en el Instituto de Investigación de Síntesis Química y Catálisis Homogénea (ISQCH), un centro mixto del CSIC y de la Universidad de Zaragoza., No

El próximo 23 de febrero tendrá lugar una nueva edición de “De copas con Ciencia” que pretende acercar la ciencia a los bares de forma divertida, y que en esta sesión contará con José Ignacio García y Scott Mitchell que nos hablarán de homeopatía y como utilizar los nanomateriales contra los microbios. La actividad organizada por los institutos de investigación ICMA e ISQCH se repetirá de forma periódica los últimos jueves de cada mes en El Sótano Mágico., No

Luis Oriol, Francisco J. Fernández y José Edelstein, como investigador invitado, que nos hablarán de los plásticos, de cómo utilizar el dióxido de carbono (CO2) que emitimos a la atmósfera como materia prima y del tiempo La actividad organizada por los institutos de investigación ICMA e ISQCH se repetirá de forma periódica los últimos jueves de cada mes en El Sótano Mágico., No

Este artículo está sujeto a una licencia CC BY-NC-SA 4.0, [ES] Este trabajo aborda la estimación de variables biofísicas de un pastizal de dehesa a partir de información óptica generada por sensores próximos y remotos. Las variables de contenido de humedad del combustible (FMC), contenido de agua del dosel (CWC), índice de área foliar (LAI), materia seca (Cm) y biomasa superficial (AGB) fueron estimadas en laboratorio a partir de muestras de vegetación tomadas simultáneamente a la adquisición de datos hiperespectrales del sensor Compact Airbone..., [EN] The aim of this paper is the estimation of biophysical vegetation parameters from its optical properties. The variables Fuel Moisture Content (FMC), Canopy Water Content (CWC), Leaf Area Index (LAI), dry matter (Cm) and Above-Ground Biomass (AGB) were estimated in the laboratory from vegetation samples collected simultaneously with the acquisition of spectral data from the Compact Airborne Spectrographic Imager (CASI) sensor and the field spectroradiometer ASD FieldSpec® 3. Spectral..., Este trabajo se ha realizado en el contexto de los proyectos BIOSPEC (CGL2008-02301/CLI) financiado por el Ministerio e Innovación y FLUχPEC (CGL2012-34383) financiado por el Ministerio de Economía y Competitividad. Agradecemos al Ministerio de Educación, Cultura y Deporte la financiación recibida a través del programa de becas FPU del investigador predoctoral José Ramón Melendo., Peer reviewed

4 pages, Anualmente en la ciudad italiana de ANCONA, en la Ribera del Cónero, costa del Adriático, se celebra una feria dedicada a diversos aspectos relacionados con la pesca. Esta Feria tenía interés sin duda desde muchos puntos de vista, pero en partiCular, porque es la única que se celebra en la zona mediterránea, donde si bien la pesca no tiene el interés económico de otras pesquerías como las realizadas en el Atlántico, Pacífico etc., si se caracterizan por la calidad del producto, por la extrema..., Peer Reviewed

Julia Herrero y Andrea Di Giuseppe participarán este jueves en la actividad organizada por los institutos de investigación ICMA e ISQCH., No

Peer reviewed

Jefe de la campaña Pere Rubiés.-- 35 pages, La campaña oceanográfico-pesquera "BENGUELA I" representa el comienzo de una nueva etapa en el conocimiento de los recursos explotables de la plataforma continental de Namibia, estudio iniciado hace unos años por el IIP, que hasta el presente se había limitado a las estadísticas de pesca y a algunos datos biológicos de las especies más importantes, [...], Peer Reviewed

The invention provides highly functionalised spiro-fused azetidinones of formula I: having a cyclohexane moiety with the desired number of protected or unprotected hydroxyl groups or carbonated structures, which are introduced with high stereo and regioselectivity, as well as processes for their obtention., Peer reviewed, Laboratorios del Dr. Esteve S.A., A1 Solicitud de patente con informe sobre el estado de la técnica

363 Pags.- Figs.- Tabls.- Maps. Juan Herrero Isern and Carmen Castañeda del Álamo, Director and Author respectively of this thesis, belong for years to the scientific staff of the Estacion Experimental de Aula Dei (EEAD-CSIC). Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), [ES] El objetivo de esta Tesis ha sido estudiar las saladas del sur de Monegros mediante datos de campo y de satélite disponibles, extrayendo información retrospectiva acerca de sus facies y de su estado hídrico. Para ello (i) se han tratado imágenes Landsat desde 1985 hasta 2000, utilizando las escasas observaciones de agua disponibles; (ii) se han integrado observaciones de campo, actuales y de otros autores, con la información suministrada por las imágenes de satélite. Con ello se han..., [EN] The aim of this Thesis has been to study the saladas of the Monegros Desert, in NE Spain, using available ground and satellite observations, which have provided worthwhile historical data and additional information about their facies and hydric status. For this, (i) Landsat imagery from 1985 to 2000 is explored, using the scarce available field records; (ii) current and past field observations are integrated with remotely sensed data for discriminating and cataloging five facies whose..., Peer reviewed

1 Pag.- 1 Fot., A raíz de la publicación por parte de WWF del informe «Modernización de regadíos. Un mal negocio para la naturaleza y la sociedad» en este documento se aclaran datos y conceptos que el informe de WWF menciona respecto del sistema regable de Riegos del Alto Aragón. Se ha es­tudiado el periodo de 2001 a 2014, considerando como período antes de la modernización los años de 2001 a 2004 y como período pos­terior a la modernización los años 2011-2014 o 2013-2014, depen­diendo de la zona estudiada., Peer reviewed

This paper describes a system of extensional faults oriented NW-SE, NNW-SSE and ENE-WSW responsible for the tectonic relief of semi-grabens in southeastern Dominican Republic. These faults constitute the natural extension of a previously recognized fault system in western Puerto Rico and the Mona Passage. Paleostress analysis carried out on the faults and fractures in the Pliocene limestone results in a minimum NE-SW stress axis, changing to SSW in the faults that affect the Pleistocene..., Este trabajo ha sido financiado por los Proyectos CGL2009-08674/BTE y GL2012-33669/BTE., Peer reviewed

In European archaeology, the malacological remains recovered in archaeological contexts have traditionally been considered almost exclusively as food waste. In other cases, this view has been broadened in order to study these remains as an expression of aspects of the social organization of the human groups, based on the use of perforated shells as objects of personal ornamentation. However, the study of these natural resources as raw materials for the manufacture of tools aimed at satisfying..., Peer Reviewed

Resumen de la ponencia presentada a los ‘Viernes Científicos’ de la Universidad de Almería, celebrada el 26 de mayo de 2017., Ponencia sobre las investigaciones en el diseño de compuestos de coordinación, principalmente de metales del grupo 11, con propiedades específicas para diversas aplicaciones en síntesis, luminiscencia, medicina o catálisis. Uno de los objetivos es la preparación a medida de compuestos de oro que posean una selectividad específica hacia células cancerígenas, es decir, la unión al átomo de oro de las moléculas adecuadas para que pueda ser transportado específicamente a las células tumorales, lo..., No

© 2015 the authors. Cerebellar GABAergic interneurons in mouse comprise multiple subsets of morphologically and neurochemically distinct phenotypes located at strategic nodes of cerebellar local circuits. These cells are produced by common progenitors deriving from the ventricular epithelium during embryogenesis and from the prospective white matter (PWM) during postnatal development. However, it is not clear whether these progenitors are also shared by other cerebellar lineages and whether..., Peer Reviewed

7 Pags.- 3 Fots.- 3 Figs.- 1 Tabl., En el presente trabajo se analizan los resul-tados de 26 evaluaciones de la distribución de agua de un aspersor aislado realizadas al aire libre y con el viento en calma en una parcela provista de cortavientos de la finca experimen-tal del CITA en Zaragoza. El aspersor utilizado fue un aspersor de impacto con el cuerpo de bronce y dos boquillas de plástico. De acuerdo a los valores de velocidad del viento, dominancia de la di-rección del viento y desviación estándar de la pluviometría recogida..., Al MCINN por la financiación de los proyectos de investigación AGL2007-66716-C03-01/02 y AGL2010-21681-C03-01/03. Al Pro-grama FPI-MICINN por la concesión de una beca doctoral a Talel Stambouli., Peer reviewed

Cortical axons innervate their brainstem target, the basilar pons, by the initiation and extension of collateral branches interstitially along their length. To address whether a diffusible pons-derived chemoattractant controls these events, we used cocultures in collagen matrices and time-lapse microscopy. Pontine explants enhanced by 5-fold the de novo initiation of transient branches along cortical axons; most branches were directed toward pons. Of the branches extended toward pons, 2%-3%..., Peer Reviewed

Cyclic sediments observed throughout the Mediterranean during the Late Miocene have been related to precessional forcing of ocean stratification. Individual couplets, typically 2-m-thick sequences of sapropels and diatom-rich marls, can be reliably traced from western Spain to Crete, and were formed in restricted marginal basins. Micropaleontological evidence indicates paradoxically that the organic carbon-rich sapropels were formed under low productivity conditions marked by surface water..., We thank the donors of the Petroleum Research Fund,administered by the American Chemical Society,the US National Science Foundation (Grant OCE9711957 to G.M.F.),the Fulbright Organization,and the DGCYES project PB98^0288 for support of this research., Peer Reviewed

Número abril-septiembre, En las páginas 367 a 384 del tomo extraordinario de EOS, editado en 1950, mi excelente amigo don Eugenio Morales Agacino publica un artículo sobre los Podismini de la Península Ibérica (Orth. Acrid.), en el que erige una nueva especie, desvirtuando para ello las Reglas Internacionales de Nomenclatura Zoológica hasta tal punto que me siento compelido a contradecirle, y ello por dos razones importantes„ La primera estriba en que habiéndole alabado yo públicamente (Graellsia, t. III, página 95,..., Peer reviewed

Multiple sclerosis is a demyelinating disease that affects ~2,000,000 people worldwide. In the advanced stages of the disease, endogenous oligodendrocyte precursors cannot colonize the lesions or differentiate into myelinating oligodendrocytes. During development, both FGF-2 and Anosmin-1 participate in oligodendrocyte precursor cell migration, acting via the FGF receptor 1 (FGFR1). Hence, we performed a histopathological and molecular analysis of these developmental modulators in postmortem..., Peer Reviewed

Biosensors can be excellent analytical tools for monitoring programs working to implement legislation. In this article, biosensors for environmental analysis and monitoring are extensively reviewed. Examples of biosensors for the most important families of environmental pollutants, including some commercial devices, are presented. Finally, future trends in biosensor development are discussed. In this context, bioelectronics, nanotechnology, miniaturization, and especially biotechnology seem to..., This work has been supported by AWACSS (EVK1-CT-2000-00045) and by RADAR (QLRT-2000-01670). Sara Rodriguez acknowledges Ministerio de Ciencia y Tecnología (Project PPQ 2000-3006-CE) and I3P Program (Itinerario integrado de inserción professional; co-financed by CSIC and European Social Funds). María J. López de Alda acknowledges a Ramon y Cajal contract from theSpanish Ministry of Science and Technology., Peer reviewed