Resultados de investigación

Sota el marc del projecte Estudi i Recuperació de Patrimoni Musical, aquest dataset conté dos arxius: Transcripció del manuscrit original de Francesc Queralt Enregistrament de la peça interpretada per: - Eva del Campo, orgue positiu. Orgue positiu construït per Gerrit Klop el 2022 - Ricart Renart, violí I. Violí construït per Joseph Massaguer el 1753 - Marta Guillen, violí II. Violí construït per Giuseppe Tenneriello el 2009 - Guillermo Turina, violoncel. Violoncel construït per Marchal a finals del segle XVIII - Martí Doñate (tenor), Peer reviewed

Sota el marc del projecte Estudi i Recuperació de Patrimoni Musical, aquest dataset conté dos arxius: Transcripció del manuscrit original de Joaquim Laposaria Alsina Enregistrament de la peça interpretada per: - Dani Espasa, piano de taula Miguel Slocker de 1831, cedit pel Museu de la Música de Barcelona., Peer reviewed

These timecourses and datasets correspond to the publication: Lokanathan-Balaji et al. “DNA binding and bridging by human CtIP in the healthy and diseased states” bioRxiv 2023 (https://doi.org/10.1101/2023.12.14.571649), Fig4+5_Datasets.zip and Fig4+5_Timecourses.zip folders contain all the datasets and the individual timecourses, respectively, for all the conditions addressed in Figures 4 and 5: - Bare DNA - DNA + wild-type CtIP - DNA + lambda CtIP - DNA + R100W CtIP - DNA + deltaC608 CtIP - DNA + deltaC782 CtIP - DNA + deltaN500 CtIP - DNA + deltaN790 CtIP Supp_FigS4_Datasets.zip and Supp_FigS4_Timecourses.zip folders contain all the datasets and the individual timecourses, respectively, for all the conditions addressed in Supplementary Figure S4: - fork-end branched DNA (forked) + wild-type CtIP - fork-end branched DNA (forked) + lambda CtIP, El dataset se puede consultar y descargar en https://doi.org/10.5281/zenodo.10499058, Peer reviewed

The data is stored in python compressed array format (.npz) with the atomization energies in kcal/mol and atomic forces in kcal/mol/Ang. The data set contains five numpy arrays import numpy as np data = np.load('P+H_ThirdF.npz') data['R'] # Cartesian coordinates of nuclei (Ang.) data['E'] # Total energy (kcal/mol) data['F'] # Atomic forces (kcal/mol/Ang.) data['N'] # Number of atoms in each structure data['Z'] # Nuclear charges, This dataset was employed in the study of the reaction dynamics of H atoms reacting with P atoms in amorphous solid water. The protocol for the generation of the dataset is highlighted in the publication "Reaction dynamics on amorphous solid water surfaces using interatomic machine-learned potentials", Peer reviewed

This product provides the Finite-size Lyapunov Exponents derived from surface geostrophic velocities result from the application of the 4DVARNET algorithm (Fablet et al., 2021; resolution of the dynamical model used for the learning/training (eNATL60-BLB02) downgraded to 1/8°) to altimetry L3-data (https://doi.org/10.5281/zenodo.10908416) at a resolution of 1/72° over the Mediterranean Sea and for the period from April 2016 to July 2022. Algorithm used to compute Finite-Size Lyapunov Exponents was developed by I. Hernandez-Carrasco (Hernandez-Carrasco et al, 2011, Ocean modelling. https://doi.org/10.1016/j.ocemod.2010.12.006)., Geographical coverage: Mediterranean Sea. Grid and horizontal spatial resolution: Evenly spaced 1/72º grid. Vertical levels: Only surface level. Temporal resolution: Daily (April 2016 - July 2022). Variables: lon (1D); lat (1D); time (1D); fsle (2D)., El dataset se puede consultar y descargar en https://doi.org/10.5281/zenodo.11613002, European Space Agency: “4DMED-SEA” ProjectESA Contract No. 4000141547/23/I-DT, Peer reviewed

This product provides the Finite-size Lyapunov Exponents derived from surface geostrophic velocities result from the application of the 4DVARNET algorithm (Fablet et al., 2021; resolution of the dynamical model used for the learning/training (eNATL60-BLB02) downgraded to 1/8°) to altimetry L3-data (https://doi.org/10.5281/zenodo.10908416) at a resolution of 1/24° over the Mediterranean Sea and for the period from April 2016 to July 2022. Algorithm used to compute Finite-Size Lyapunov Exponents was developed by I. Hernandez-Carrasco (Hernandez-Carrasco et al, 2011, Ocean modelling. https://doi.org/10.1016/j.ocemod.2010.12.006)., Geographical coverage: Mediterranean Sea. Grid and horizontal spatial resolution: Evenly spaced 1/24º grid. Vertical levels: Only surface level. Temporal resolution: Daily (April 2016 - July 2022). Variables: lon (1D); lat (1D); time (1D); fsle (2D), European Space Agency: “4DMED-SEA” ProjectESA Contract No. 4000141547/23/I-DT, Peer reviewed

Peer reviewed

This study was carried out to address potential uncertainties about how point-of-care testing (POCT) improves patients’ outcomes in emergency department (ED). The main aim was to develop and validate a model based on advanced data analytics to evaluate POCT’s impact in patients’ outcomes and ED patients’ flow. We built a discrete event model simulation (DEMS) to represent workflow of a Spanish ED. Historical data from ED, published evidence and expert estimates were used to support the model. Different scenarios of progressive utilization of POCT in patients’ care triaged as Emergency Severity Index (ESI) level 3 were compared to standard-of-care (SoC) in terms of time-to-first medical intervention (TFMI), time-to-disposition decision (TDD), total length of stay (LoS) and patient workflow. In POCT maximum utilization scenario (60% of ESI-3 patients), time savings reached 27.44, 14.58 and 13.96 min of TFMI, 55.77, 13.64 and 13.97 min of TDD and 89.60, 18.55 and 13.98 min of LoS (ESI-3, 4 and 5 patients, respectively). Statistically significant reductions were found for all time outcomes in every POCT scenario for ESI-3, 4 and 5 patients. Internal validation didn’t show differences between model results and real data. Simplifications were made due to theoretical nature of computer-simulation models. Some input data and assumptions regarding individual process times were derived from interviews. Theoretical distributions were assumed; other activities outside the ED were considered as a disruption to the system; finally, findings reflect experience of a single ED. Advanced data analytics has become a useful tool in analyzing lots of processes. Our study showed that advanced data analytics has become an exceptional tool in clinical laboratories and exemplifies how POCT incorporation in ED for care of ESI-3 patients reduces physicians’ workload and waiting times of ESI-3, 4 and 5 patients, thus optimizing the patients’ medical journey., This work was supported by Roche Diagnostics. Roche Diagnostics played no role in the study design; in the collection, analysis, and interpretation of data; in the final writing of the report; or in the decision to submit the report for publication., Peer reviewed

Severe water stress can lead to hydraulic disfunction, reducing plant conductance or even causing death. Some plants exhibit hydraulic vulnerability segmentation between organs to reduce this risk. However, its role in influencing drought tolerance and resistance in grafted plants, such as grapevine, remains unclear. This study aimed to evaluate the physiological responses, drought tolerance, hydraulic vulnerability segmentation and xylem anatomy of two-year-old Vitis vinifera cv. Tempranillo scion grafted onto two rootstocks: 110-Richter (110R) and Sélection Oppenheim 4 (SO4). After subjecting the plants to drought conditions until the onset of embolism in the leaf (P12), we analysed the physiological consequences during recovery. Grapevine exhibits hydraulic vulnerability segmentation not only within scion organs but also between the scion and rootstock. Although no differences in scion drought tolerance and embolism resistance were observed between combinations, Tempranillo-110R exhibited higher leaf minimum conductance, leaf P12 values and root biomass. In contrast, Tempranillo-SO4 displayed larger vessel diameter and higher hydraulic conductance. These differences may explain the slower recovery of Tempranillo-110R compared to Tempranillo-SO4, which showed higher stomatal and root-to-stem hydraulic conductance. These findings suggest that rootstock selection should consider drought resilience alongside vigour and productivity, especially given the increasing the concurrence of severe drought periods due to climate change., European Regional Development Fund: MCIN/ AEI/10.13039/501100011033, PID2021-123305OB-C32-FEDER A way to make Europe, Peer reviewed

Este trabajo presenta una síntesis del conocimiento arqueológico publicado a partir de las investigaciones en el yacimiento de la motilla de El Retamar (Argamasilla de Alba, Ciudad Real, España), adscrito a la Edad del Bronce de La Mancha. Se propone una reinterpretación del sitio a la luz de los datos más recientes, su documentación integral y un análisis del espacio construido basado en la documentación tridimensional del yacimiento mediante fotogrametría digital. También se describen en detalle los resultados de las primeras actuaciones de conservación-restauración llevadas a cabo en esta motilla con el objetivo de frenar su deterioro tras décadas de abandono., Peer reviewed