Resultados de investigación

These data are associated to the paper with the same title of the authors, and are structured according to the figures in the paper: http://hdl.handle.net/2117/335727, The use of Cold Atmospheric Plasma (CAP) in oncology is being recently studied as a novel potential anti-cancer therapy. However, the beneficial effects of CAP for treating osteosarcoma have mostly been demonstrated in 2-dimensional cultures of cells, which do not mimic the complexity of the 3-dimensional (3D) bone microenvironment. In order to evaluate the effects of CAP in a relevant context of the human disease, we developed a 3D tissue-engineered model of osteosarcoma using a bone-like scaffold made of collagen type I and hydroxyapatite nanoparticles. Human osteosarcoma cells cultured within the scaffold showed a high capacity to infiltrate and proliferate and to exhibit osteomimicry in vitro. As expected, we observed significantly different functional behaviors between monolayer and 3D cultures when treated with Cold Plasma-Activated Ringer’s Solution (PAR). Our data reveal that the 3D environment not only protects cells from PAR-induced lethality by scavenging and diminishing the amount of reactive oxygen and nitrogen species generated by CAP, but also favours the stemness phenotype of osteosarcoma cells. This is the first study that demonstrates the negative effect of PAR on cancer stem-like cell subpopulations in a 3D biomimetic model of cancer. These findings will allow to suitably re-focus research on plasma-based therapies in future

This dataset contains data from a population-representative survey examining various factors relating to digital exclusion (particularly digital mobility exclusion). The survey was conducted with 601 adult participants in the Barcelona Metropolitan Area of Spain in 2020. This dataset is part of a series of 5 datasets which used the same questionnaire (translated into different languages) in different countries in Europe.

The simulation represents the behaviour of the availability and disponibility during his life cycle of a medical device in Matlab version, We can determine the downtime that the equipment has suffered, and the following code permit printing the behavior availability machine to his out of service frequency during his life cycle. That could be interesting to predict his evolution monitoring his possible availability.

This dataset contains data from a population-representative survey examining various factors relating to digital exclusion (particularly digital mobility exclusion). The survey was conducted with 1002 adult participants in Italy in 2020. This dataset is part of a series of 5 datasets which used the same questionnaire (translated into different languages) in different countries in Europe.

This dataset is related to the protocol developed by the authors on the evaluation of the effects of cold atmospheric plasma and plasma-treated liquids in cancer cell cultures. More specifically, the data correspond to the anticipated results presented in the paper submitted to Nature Protocols, The present dataset corresponds to the anticipated results that can be obtained following the protocol described in the article. In particular, dataset corresponding to Figure 8 presents the absorbance values from the WST-1 cytotoxicity assay as a function of the well size where the experiment is performed. Data from Figure 9b show absorbance values from the WST-1 cytotoxicity assay as a function of the treatment time. Data from figure 9c-e show the absorbance or fluorescence values obtained in the experiments to quantify RONS, together with the values from the calibration curves. Data fromfigure 10 a provide the list and values of mRNA fold induction of the genes analyzed, and data from figure 10c show the pixel intensity obtained for the phospho-kinase antibody array.

This dataset contains data from a population-representative survey examining various factors relating to digital exclusion (particularly digital mobility exclusion). The survey was conducted with 1010 adult participants in Germany in 2020. This dataset is part of a series of 5 datasets which used the same questionnaire (translated into different languages) in different countries in Europe.

Albarelo o tarro de farmacia (CE2978-132) producido en los talleres de Fajalauza (Granada, España). Ha sido modelado a torno y cocido en una atmósfera oxidante. Tiene una forma cerrada, parte de un labio redondeado y borde con orientación vertical que continúa en un cuello vertical y un hombro curvilíneo cóncavo. El cuerpo es recto, estrechándose levemente en la parte intermedia, la base es peraltada. Está decorado con un escudo coronado que contiene una granada con hojas y tallo. Presenta un espacio para escribir el nombre del contenido. * Cronología: 1600-1699. * Depósito: Museo Arqueológico y Etnológico de Granada. [FAJALAUZA-Hd](https://acortar.link/bNsUsm) Colaboran: [PRINMA](http://blogs.ugr.es/prinma/), [UGR](http://www.ugr.es), [Fundación Fajalauza](https://acortar.link/shJ8ps) , [Museo Arqueológico y Etnológico de Granada](https://acortar.link/DF0cOC), [Patronato de la Alhambra y Generalife](https://acortar.link/FcstHW) Fotografías y modelo: [Francisco Lara Piñera](https://acortar.link/Bam3Op) Source: Objaverse 1.0 / Sketchfab

https://www.youtube.com/watch?v=TarEiUoefxo, Semana Santa y degeneración del entorno urbano

Fuente producida en los talleres de Fajalauza (Granada, España). Ha sido modelada a torno y cocida en una atmósfera oxidante. Tiene una forma abierta, parte de un labio redondeado y borde exvasado con el cuerpo con un perfil troncocónico abierto y base plana rehundida. Está esmaltada en blanco, tanto en el interior como en el exterior. Borde decorado con una cenefa en azul. Su parte interna está cubierta de cemento, fruto de su uso en el taller. * Cronología: Siglo XXI. * Depósito: Talleres de la Fundación Cerámica Fajalauza Cecilio Morales. [FAJALAUZA-Hd](https://acortar.link/bNsUsm) Colaboran: [PRINMA](http://blogs.ugr.es/prinma/), [UGR](http://www.ugr.es), [Fundación Fajalauza](https://acortar.link/shJ8ps) , [Museo Arqueológico y Etnológico de Granada](https://acortar.link/DF0cOC), [Patronato de la Alhambra y Generalife](https://acortar.link/FcstHW) Fotografías y modelo: [Francisco Lara Piñera](https://acortar.link/Bam3Op) Source: Objaverse 1.0 / Sketchfab

Participación en el reportaje de ARTE dedicado a Théophile Gautier en Granada